Probiotics Flashcards
What is a probiotic
live microorganisms which when given in good amount —- benefit for host
—- normally B: lacto or bifido; can be yeast
—- Genus: species: strain
What is a prebiotic
nondigestable shit (fiber) that helps with growth of micro
Synbiotics
pro and pre combo
What probiotics can be used for ABX diarrhea
Culturelle
Florastor
Biogaia
BioK+
What probiotics can be used for infectious diarrhea
Kids
- culturelle
florastor
What probiotics can be used for travellers diarrhea
Florastor
What probiotics can be used for C dif
Florastor
BioK+
What probiotics can be used for H pylori
Florastor
What probiotics can be used for colic
Biogaia
What probiotics can be used for IBS
Align and Activia
What probiotics can be used for constipation
Activia
SEs (general ) of probiotics
well tolerated —- maybe GI effects
rare: fungemia, bacteremia, sepsis
- normally if compromised health
Fxn of probiotics in GI disease
help restore + modify gut micro
—- compete for nutrients, decrease pathogen adherence, reduce pH, stimulate immune
T or F: Probiotics can help prevent and treat ABX associated diarrhea
T
- generally in infants/kids
—- generally reduce risk of associated ABX D
** studies by themselves not stat sig but together —— are**
What does cochrane say about ABX diarrhea
greater effect with higher doses
- may decrease duration by 1 day
best strains with evidence: L. rhamnosus, S. bouldardii
Lacto —- most common
Adults: BioK, Florastor, Culturelle
Kids: biogaia, florastor, culturelle
C Dif + probiotics
moderately certain that it helps prevent CDAD (diarrhea)
- doesn’t decrease incidence of infection with CD though
** help prevent diarrhea not infection
— don’t know optimal strain or dose
T or F: Probiotics help treat CD diarrhea
F —- help with prevention
Infectious diarrhea + probiotics
has no impact on reduction of risk of diarrhea
— use to think helped but now updated + opinion changed
** don’t reduce risk or duration
IBS + probiotics
IBS: fxnal disorder with pain, diarrhea or constipation
— probiotics works + help with symptoms and pain
B> R: so try for 4 wk period
AD + probiotics
- no evidence to support use for treatment
— evidence to support use in prevention : use during pregnancy/ during infancy —- exposure to microbes decrease S to AD
Best evdience: LR GG, or combo products with L +B
Colic + P
low evidence : may reduce crying time
IBD: ulcerative
may help with remission
BV
oral or V with lacto
prevention of RI
some evidence that may reduce URTI in kids
