Principles of surgical care Flashcards

1
Q

System used to classify surgical risk

A

ASA risk classification

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2
Q

Categories of ASA risk

A
l - healthy
ll - minor disease (mild HPT)
lll- Sever non-incapacitating disease
lV - Incapacitating systemic disease (heart failure)
V - Moribund
E - Emergency surgery
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3
Q

Only routine test required for GA

A

Hb

Urine - glucose and protein.

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4
Q

Pathophysiological response to surgery

A
  1. Increased sympathetic innervation (tachy and vasoconstiction)
  2. Increase glucagon and cortisol (gluconeogenesis)
  3. Aldosterone + ADH + RAAS = sodium and water retention
  4. Decreased insulin
  5. Increased metabolic rate and acute phase proteins
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5
Q

Mendelson’s syndrome

A

Chemical pneumonitis caused by aspiration during anaesthesia

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6
Q

Average maintenance fluid requirements

A

30ml/kg/24hrs

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7
Q

Name the four stages of shock

A
  1. Initial
  2. Compensatory
  3. Progressive
  4. Refractory
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8
Q

Types of shock

A
  1. Hypovolaemic
    · Most common type
    · Due to insufficient circulating volume, most commonly blood loss
  2. Cardiogenic
    · Failure of the heart to pump effectively
    · Massive myocardial infarction, arrhythmias, cardiomyopathy, cardiac valve problems are
    common causes
3. Distributive
‘Relative hypovolaemia’ as a result of dilation of blood vessels which diminishes the systemic vascular
resistance
· Septic shock — caused by
overwhelming systemic infection
· Anaphylactic shock ~ anaphylactic
reaction to an allergen, antigen,
drug
· Neurogenic shock — trauma to
spinal cord with loss of autonomic
and motor reflexes
4. Obstructive 
The flow of blood is obstructed which impedes circulation
· Cardiac tamponade
· Tension pneumothorax
· Massive pulmonary embolism
· Aortic stenosis
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9
Q

Causes of cardiogenic shock

A

Massive myocardial infarction, arrhythmias, cardiomyopathy, cardiac valve problems

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10
Q

Causes of distributive shock

A

· Septic shock — caused by overwhelming systemic infection
· Anaphylactic shock - anaphylactic reaction to an allergen, antigen, drug
· Neurogenic shock — trauma to spinal cord with loss of autonomic and motor reflexes

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11
Q

Causes of obstructive shock

A

· Cardiac tamponade
· Tension pneumothorax
· Massive pulmonary embolism
· Aortic stenosis

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12
Q

What two major criteria must be met to diagnose septic shock?

A

Evidence of infection

Refractory hypotension

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13
Q

Which minor criteria must be met for diagnosis of septic shock

A

Two of the following:
Tachpnoea (>20) or pCO2 12
HR > 90
Temp 38

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14
Q

Most common cause of septic shock

A

endotoxin-producing gram-negative bacilli

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15
Q

Resus in septic shock must begin immediately when..

A

Hypotensive or metabolic acidosis or serum lactate >4 mmol/L

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16
Q

Treatment plan for septic shock

A
Oxygen administration/ airway support
Volume resus
Early antibiotics
Rapid source identification
Support major organs
17
Q

Targets for volume resus in septic shock

A
CVP 8 - 12 mmHg
MAP > 65 mmHg (adrenalin)
Urine output > 0.5ml/kg/hr
Haematocrit > 30%
CV or mixed venous > 70% and 64% respectively
18
Q

What connects the greater and lesser sacs of the peritoneal cavity?

A

Foramen of Winslow

19
Q

Nerve supply of:

  1. Parietal peritoneum
  2. Visceral peritoneum
A
  1. Afferent somatic (localised sharp pain)

2. Afferent autonomic (poorly localised and dull) NB sensitive to distension/ischaemia but not temp and pain

20
Q

Two clinical categories of peritonitis

A

1) Primary peritonitis is an infection of the peritoneum occurring de novo without obvious intra-abdominal
pathology.

2) Secondary bacterial peritonitis is a purulent inflammation of the peritoneum due to contamination following a complication of a preexisting primary intra-abdominal process such as perforated peptic
ulcer, ruptured appendix, a disrupted anastomotic suture line or as consequence of bacterial contamination from external sources (eg. penetrating injury).

21
Q

In whom does spontaneous bacterial peritonitis occur?

A

Alcoholic cirrhosis with ascites (prognosis poor due to poor baseline)

22
Q

Most common organisms in SBP?

A

E coli

pneumococci

23
Q

Most common cause of secondary peritonitis

A

ruptured appendix / direrticuli

24
Q

What can cause 2ndry peritonitis?

A
Primary abdo disease
Trauma
Obstruction
Malignancy
Perforated ulcer/appendix/diverticulus
Bowel ischaemia
PID
Surgery (current or previous)
25
Most commonly cultured orgs in 2ndry bacterial peritonitis
E coli | B fragilis
26
What is the pathophysiology of bacterial peritonitis?
Fluid shift - from intravascular space to peritoneal space Ileus Endocrine - RAAS and Adrenal stimulation CVS - Marked vasoconstiction -> lactic acid in peripheries -> metabolic acidosis which kidneys struggle to clear as prerenal failure Resp - Increased demand and less space due to distension Kidney - pre-renal plus sodium and water retention
27
Essential management steps in peritonitis
Fluid resus Antibiotics Decompensation of GIT Exploratory laparotomy if required. NB respiratory function must be monitored
28
Which antibiotics are used in peritonitis
Empiric triple therapy Aminoglycosides - Gram negs (cleared renally {give third gen cefs} + ototoxicity) Metronidazole - Anaerobes Ampicillin - Enterococci
29
Intra-abdominal abscess formation is | due to either:
``` 1. effective localization of the primary pathology such as an appendiceal or diverticular abscess 2. a sequel or complication following generalized peritonitis or 3. intraperitoneal contamination secondary to external trauma or complicating previous surgery ```
30
The major intraperitoneal anatomic spaces in which abscesses commonly localise are:
1. Subphrenic space 2. Subhepatic space (Morrison's pouch) 3/4. Paracolic gutters 5. Interloop 6. Appendiceal 7. Pelvic
31
Most useful investigation to identify intraperitoneal abscess
U/S or CT