Aneurysms Flashcards
Define ectasia
Focal dilatation of an artery
Define aneurysm
Focal dilatation of an artery >1.5x the normal calibre
Define arteriomegaly
DIFFUSE dilatation of an artery
Define aneurysmosis
Multiple aneurysms along a normal calibre artery
Causes of aneurysms
Degenerative (non-specific, fibromuscukar displasia, intimomedial mucoid degeneration)
Infective (HIV, TB, Syphylis, Salmonella)
Immunologic (SLE, RA)
Vasculitic (Takayasu, Becgets, giant cell arteritis, Kawasaki, Panarteritis nodosa)
Connective tissue disorders (Marfan’s
Trauma
Post stenotic (thoracic outlet syndrome, Coarctation)
Congenital (Tuberous sclerosis, Turner’s, Menke’s)
Most common site for abdominal aneuryms
Infrarenal abdominal aotra
Complications of aneurysms
Rupture (usually aortic) Acute/chronic thrombotic occlusion (usually peripheral) Thromboembolism Pressure on external structures Spontaneous fistulation
Define true aneurysm
The wall of the aneurysm contains all the layers of the artery
Define false aneurysm
The wall of the aneurysm contains the adventitia and compressed surrounding connective tissue only.
How to classify aneurysms
Anatomical (aortic/ non-aortic) Type (true/ false) Shape (fusiform/ saccular) Size (small [4-5.5cm] / large [>5.5cm]) Aetiology
Risk factors for aneurysms
HPT Smoking Family history Previous aneurysm Age Sex (Males 5:1) Race (white)
Symptomatic AAA
Vague abdo pain Backache Vomiting (duodenal compression) Constipation Flank pain (ureteric compression) Chronic venous disease
Complicated AAA
Acute lower limb ischaemia (thrombus) Blue toe syndrome (emboism) Rupture Aortoenteric fistula Aortocaval fistula
First line investigation to diagnose AAA
Abdominal duplex ultrasound
Investigation used for treatment planning of AAA
CT angiogram
In whom is screening for AAAs recommended
White males >65yr
Elderly with peripheral anuerysms
Documented TAAAs
Family history
Rationale for screening
· The overall mortality for a ruptured AAA is ~ 90%
· Approximately 70% of patients are asymptomatic prior to rupture
· Up to 75% die before reaching
· Operative mortality ruptured AAA is ~ 50%
· Operative mortality for elective AAA repair is 50% AAA-related mortality
reduction using screening programmes
Indications for surgical intervention in AAA
· All symptomatic AAAs
· All complicated AAAs
· Asymptomatic AAA > 5.5 cm in males
· Asymptomatic AAAs > 5 cm in females
· Small AAAs on surveillence with rapid enlargement ( > 1
cm after 1 year on repeat scan)
· Asymptomatic AAA with a large iliac aneurysm > 3cm
· Asymptomatic saccular AAA > 3 cm (these tend to rupture at smaller diameters)
Management for AAA
Lifestyle modifications
Surveillance
Antiplatelet/lipid lowering drugs
Surgery (if indicated) [open or endovascular]
In whom is open repair of AAA the standard of care?
Young
Fit
Life expectancy > 5yrs
Classic triad of AAA presentation
Sudden onset severe back pain
Shock
Pulsatile abdo mass
What scoring system is used to evaluate risk of intervention in AAA
Hardman risk index (1 = 20%, 2 = 70%, >3 = 100% mortality)
- Age >79
- BP 179 (190)
- Hb
Site for aneurysms in order of prevalence
AAA, TAAA, TAA, Popliteal, Femoral
Rare: Subclavian, Extracrnial carotid, Mesenteric, Renal artery