principles of phys Flashcards

1
Q

R. heart vs L. heart

A

R. heart is deoxygenated blood that takes low pressure blood to the lung to get O2 and get rid of CO2

L. heart accepts oxygenated blood and pushes it out at high pressure to body tissues

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2
Q

organization of body

A

kidney takes out the junk (urine)

Endocride glands put hormones into the blood

Liver helps synthesis and metabolism

GI tract absorbs and defecates

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3
Q

Peripheral nervous system

A

Afferent: somatic (touch), viceral (something is wrong in organ), special (sight)

Efferent: somatic (moves hand), autonomic (sympathetic, parasympathetic, enteric

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4
Q

Somatic PNS

A

-a single neuron between CNS and muscle

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5
Q

Autonomic PNS

A

2 neuron chain between CNS and efector organ
innervates smooth and cardiac muscle, glands, GI, NOT skeletal muscle
can be excitatory or inhibitory

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6
Q

ANS

A

para symp has long pre and shrt post

sym has short pre then long post

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7
Q

Homeostasis

A

Constancy of internal environment- maintained by feedback loops that detect and correct a deviation of set point

Control mechanims and feedback:
Neg feedback: system returns back to normal
Pos feedback: stimulus causes system to more of the same (vicious cycle)

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8
Q

Gain equation

A

Gain=correction/remaining error

with help- without help) / (with help - normal

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9
Q

Decrease body temp

A

smooth muscle in skin blood vessels contract to minimize heat loss

Skeletal muscle contracts shivering byt increasing heat production

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10
Q

Baroreceptor reflex

A

Baroreceptor senses pressure change, stimulates brain medulla vasomotor center –> sympathetic NS–> blood vessels will change according

if there are no baroreceptors bp goes up bc the brain senses that there is 0 blood pressure

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11
Q

Mass balance

A

essentially what goes in must come out

stable state Gain is equal to the loss

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12
Q

Tissue exchange

A

Simple diffusion, facilitated diffusion, active transport

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13
Q

Secondary active transport

A

Co transport: when one solute goes from high to low, and carries another INTO the cell against concentration gradient

Counter transport: when one solute goes from high to low, and carries another OUT OF the cell against concentration gradient

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14
Q

Hematocrit Hct

A

its the percentage of red blood cell mass to the whole blood, so if only plasma goes up hct goes down, if everything is lost (ie bleeding ) hct stays the same

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15
Q

Metabolism

A

Substances are cleared from blood specifically the rate that its done at is the metabolic clearance rate MCR

The higher the MCR, the faster something is cleared and the shorter the half life

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16
Q

Half life influencers

A
  1. chemical class
  2. size
  3. plasma protein binding
  4. renal handling
17
Q

Plasma binding vs FREE

A

ITS THE FREE thats biologically active thats a sample, usually theres a lot more bound than free and dissolved in plasma

The body will respond to free active form

18
Q

Surfactant

A

Surface tension is releaved in the alveolars that reduces the surface tension and keeps the compliance high

19
Q

compliance

A

change of volume/ change of pressure

20
Q

Osmolality vs osmolarity

A

Biologically theyre kinda the same, osmolality osm/kg of liquid

1M of NaCl= 2 osm

21
Q

oncotic pressure

A

the pressure of solutes that pull water into the blood system

22
Q

Starling forces

A
  1. Capillary hydrostatic pressure (Pc) water pusing our of vessel
  2. Interstitial fluid hydrostatic pressure (Pif) water coming into the capillary from body INSIGNIFICANT
  3. Osmotic (Ñc) force solutes pulling in water in cappilaries
  4. Osmotic (Ñif) force of solutes pulling water out of capillaries
23
Q

Resistance in blood flow

A

Flow (F)= change P/ resistance

in series adds up
in parallel it divides

24
Q

Nephron summary

A

Glomerulus: filtration (GFR)

Proximal tubule: bulk reapsorption

Distal tubule: fine tuning of reabsorption and sectretion using hormonal control