Principles of Oral Surgery Flashcards
Causes of tissue damage?
- Physical (insicion, cutting, crushing) 2. Chemical (Non-physiologic pH, induced ischamiea)
What is epithelialization?
Growth of the epithelium over a denuded surface
What are the stages of wound healing
- Inflammatory stage - initial haemostasis
- Fibroplastic stage
- Remodelling stage
What are factors that impair wound healing
- Foreign material
- Necrotic tissue
- Ischemia
- Tension
What is healing by primary intention?
Occurs when the edges of a wound (in which there is no tissue loss) are placed and stabilized in essentially the same anatomic position they held before injury and are allowed to heal
What is healing by secondary intention
Occurs when a gap is left between the edges of an incision or laceration, or when tissue loss has occurred, preventing approximation of wound edges (Extractions)
What is healing by tertiary intention
Refers to the healing of wounds with tissue grafts to cover large areas of missing tissue
5 healing stages of extraction sockets
- Red and white blood cells form an initial blood clot immediately after extraction is completed
- Within few days blood clot begins to break down via fibrinolysis. Blood clot transforms into granulation tissue
- Granulation tissue is replaced with connective tissues
- Calcification commences - osteoid formation at base of socket, most of the alveolus filled with woven bone. Complete epithelial closure of the socket
- Complete bony fill
What is bony healing by primary intention
Occurs when the bone is incompletely fractured (greenstick fracture) or when a surgeon closely reapproximates and rigidly stabilizes the fractured ends of a bone (anatomic fracture reduction)
Benefit = minimal callous formation, increased speed of healing, less scar tissue formation
What is bony healing by secondary intention
Occurs when bone is fractured and the free ends are more than 1 mm apart
Disadvantage = larger bony callous, decreased speed of healing, and increased scar tissue formation
3 types of nerve damage
- Neuropraxia
- Axonotmesis
- Neurotmesis
What is neuropraxia
Compression or blunt injury to the nerve - segmental demyelination
What is Axonotmesis
Compression or blunt injury to the nerve - disruption of myelin sheath and nerve cell axon
What is neurotmesis
Severe contusion, stretching or laceration - disruption of myelin sheath, nerve cell axon, and endo/peri/epineurium
Two phases of nerve healing
- Degeneration
* Segmental degeneration
o Where the myelin sheath is dissolved in isolated segments - Regeneration
* Can begin almost immediately after nerve injury
* The proximal nerve stump sends out a group of new fibers (growth cone) which progresses at a rate of 1.0 to 1.5 mm per day, and continues until the site innervated by the nerve is reached, or (more often) blocked by fibrous connective tissue or bone