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neurology > principles neurology > Flashcards

principles neurology Flashcards

1
Q

away from CNS

A

efferent

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2
Q

towards CNS

A

arrerent

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3
Q

what is a ganglion

A

a group of nerve cell bodies that house synapses

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4
Q

route of parasympathetic nerves

A

cranium - sacrum

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5
Q

parasympathetic cranial nerves

A

CN3, 7, 9, 10

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6
Q

parasympathetic neurotransmitter

A

ACh

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7
Q

parasympathetic receptor

A

nicotinic

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8
Q

short post ganglionic

A

ACh neurotransmitter, Muscularinic receptor

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9
Q

functions of the parasympathetic division

A

slow HR, lower BP, arousal, salivation, lacrimation, urination, digestion and defecation

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10
Q

short preganglionic fibre of sympathetic is from

A

thoracolumbar

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11
Q

preganglionic sympathetic receptor and neurotransmitter

A

ACh and nicotinic receptor

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12
Q

long post ganglionic symapthetic

A

NA nuerotransmitter activates G protein coupled adrenics

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13
Q

functions of the sympathetic system

A

increases HR and force, reduces GI motility, contrictionof sphinters, vasoconstriction but relaxation in skeleatl muscle adrealine release from the adrenal galnd, ejaculation, relaxes bronchi and decreases mucus production

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14
Q

preganglionic nicotinic cholinergic

A

central cation conducting ligand gated channel

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15
Q

post ganglionic muscarinic

A

activated by G protein receptors

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16
Q

g protein of M1

A

Gq

17
Q

effect of M1

A

increased gastric acid secretion

18
Q

g protein of m2

A

Gi

19
Q

effect of M2

A

decreased HR

20
Q

G protein of m3

A

GQ

21
Q

effect of M3

A

increased salvary secretion and bronchial smooth muscle contraction

22
Q

sympathetic nicotinic cholinergic

A

5 glycoprotein subunits form a central cation conducting channel activated by lingand gated cahnenls

23
Q

noradrenaline trasnmission

A

adrenoceptor activation, NA reuptake by transporters u1 and U2

24
Q

metabolism of NA

A

monoamine oxidase MAO and catechol-O-methyltransferase COMT

25
Q

beta 1 receptor effect

A

increased HR and force

26
Q

beta 2 receptor effect

A

bronchial and vascular smooth muscle relaxation

27
Q

alpha 1 receptor g protein

A

Gq

28
Q

alpha 2 receptor g protein

A

Gi

29
Q

alpha 1 receptor effect

A

vascular smooth muscle contraction

30
Q

alpha 2 receptor effect

A

inhibits NA release

31
Q

cocaine effect of ANS

A

adrenoceptor stimulation, peripheral vasoconstriction a1 and cardiac arrhytmias b1

32
Q

amphetamine effect on ANS

A

adrenoceptor stimulation same as concaine ( constricts and causes cardiac arrhytmias

33
Q

effect of atenolol on ANS

A

selective competitive antagonist of b1 adrenoceptors

34
Q

effect of atropine on ANS

A

competitive muscularinic ACh receptor antagonist - blocks parasympathetic stimulation

neurology (2 decks)

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