Principles Flashcards
which Ig is found in mucosa
IgA
what is IgA
secretary
what is IgM
Most abundant
which bacteria produces endotoxin
gram negative
which bacteria produces exotoxin
gram positive
which antibiotics are used from gram positive cover
glycopeptides
what are causes clubbing
cyanotic heart disease, lung disease, UC/Crohns, biliary cirrhosis, birth defect, infective endocarditis, neoplasm, GI malabsorbtion
low Km
only need a small amount for reaction to successfully occur (higher affinity)
high Km
needs lots for reaction to be successful
Staph aureus
Flucloxacillin
Methicillin resistant Staph (MRSA)
Vancomycin or Teicoplanin
Nosocomial pneumonia (severe)
IV amoxicillin + metronidazole + gentamicin
Nosocomial pneumonia (mild)
Amoxicillin + metronidazole
CAP (CURB 0-2)
Amoxicillin (if penicillin allergic, use doxycycline)
CAP (3 or more)
IV Co-amoxiclav + IV Clarithromycin
Intra-abdominal sepsis
IV amox + metronidazole + gentamicin
Recurrent/relapse C. Difficile
Fidaxomicin
C. difficile (mild)
Metronidazole
C. difficile (severe)
ORAL Vancomycin
Pneumocystis carinii(HIV patients)
Co-trimoxazole + prednisolone if bad
Acute exacerbation of COPD
1st line - Amox, 2nd line doxycycline
Legionnaire’s disease
Erythromycin or clarithromycin
Epiglottitis (h. influenzae)
Ceftriaxone
Amoebiasis Metronidazole
Giardiasis
Metronidazole