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Microbiology Hard Questions > Principles > Flashcards

Principles Flashcards

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1
Q

Describe bacteriostatic antibiotics.

A

Bind to ribosomes and hence inhibit protein synthesis.

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2
Q

Describe bactericidal antibiotics.

A

Inhibit cell wall synthesis.

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3
Q

Give the 3 main groups of bacteriostatic antibiotics.

A

Macrolides
Aminoglycosides eg gentamicin
Tetracyclines

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4
Q

Give the 3 main groups of bactericidal antibiotics.

A

Penicillins
Cephalosporins
Glycopeptides eg vancomycin

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5
Q

Give 3 examples of antibiotics which work on DNA.

A

Metranidazole
Co-trimoxazole
Fluoroquinolones

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6
Q

Give 2 examples of strict aerobes.

A

Legionella
Pseudomonas
(both are gram negative bacilli)

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7
Q

Give 2 examples of strict anaerobes.

A

Clostridium

Bacteroides

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8
Q

Beta lactamase destroys which antibiotic?

A

Amoxicillin.

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9
Q

Examples of coliforms which are gut commensals.

A

E.coli
Klebsiella
Proteus

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10
Q

Examples of coliforms which are gut pathogens.

A

E.coli 0157
Salmonella
Shigella

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11
Q

What is the treatment of choice for anaerobic infections?

A

Metranidazole.

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12
Q

What is the name of the toxin produced by E.coli 0157?

A

Verotoxin (VTEC).

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13
Q

What is the treatment of choice for a Staph Aureus Infection?

A

Flucloxacillin.

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14
Q

What is the treatment of choice for coliform infections?

A

Gentamicin.

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15
Q

Glycopeptides are only active against Gram ___ cell walls?

A

Gram positive.

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16
Q

What are the 4 antibiotics which commonly cause C diff?

A

Ciprofloxacin
Co-amoxiclav
Clindamycin
Cephalosporins

17
Q

Co-amoxiclav treats everything but what?

A

MRSA

Pseudomonas

18
Q

What test would you use to distinguish between Staph Aureus from other Staph species?

A

Coagulase test

Staph aureus = +ve

19
Q

Campylobacter is a gram _____ coccus/bacillus?

A

Negative

Bacillus

20
Q

Flucloxacillin is a ___ spectrum antibiotic and is effective against what?

A

Narrow spectrum

Staph and Strep

21
Q

Gentamicin is safe/unsafe in pregnancy and is bacteriostatic/bactericidal?

A

Unsafe

Both bacteriostatic and bactericidal

22
Q

Metranidazole is bactericidal/bacteriostatic, safe/unsafe in pregnancy and treats what?

A

Bactericidal
Safe in pregnancy
C diff and bacteroides

23
Q

Trimethaprim and sulphamethoxazole are bactericidal/bacteriostatic and form what?

A

Bacteriostatic

Co-trimoxazole

Microbiology Hard Questions (3 decks)

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