Principles

Question 1

Which Ig is found in mucosa

Answer 1

IgA

Question 2

IgA
IgM

Answer 2

SecretAtory
Most abundant

Question 3

Which bacteria produces endotoxin

Answer 3

Gram neg

Question 4

Which bacteria produces exotoxin

Answer 4

Gram pos

Question 5

Which antibiotics are used from gram positive cover

Answer 5

Glyopeptides

Question 6

Causes of clubbing

Answer 6

CLUBBING
Cyanotic heart disease
Lung disease
UC/Crohns
Biliary cirrhosis
Birth defect
Infective endocarditis
Neoplasm (Hodgkins)
GI malabsorption

Question 7

Low Km
High Km

Answer 7

Low - only need a small amount for a reaction to successfully occur (HIGHER AFFINITY)
Higher - need lots for reaction to be successful

Question 8

Apparent volume of distribution equation

Answer 8

𝑉 =𝐷𝑜𝑠𝑒/[𝐷]𝑃
Dp is drug plasma concentration

Question 9

Elimination half-life equation

Answer 9

𝑡1⁄2 = 0.693∗𝑉𝐷/𝐶𝐿

Vd is volume of distribution
Cl is clearance

Question 10

Dosage rate for IV infusion equation

Answer 10

𝐷𝑅= [𝐷]p𝑆𝑆 ∗ 𝐶𝐿

Dr is dosage rate
[D]pSS is the drug plasma concentration at a steady state
Cl is the clearance

Question 11

Gram negative wall and stain

Answer 11

Thinner peptidoglycan layer
Stains pink
Escherichia and salmonella are two examples

Question 12

Gram positive wall and stain

Answer 12

Thick peptidoglycan layer
Stains purple
Staphylococcus and streptococcus are all usually positive