Principle Of Growth

Question 0

Where does the growth hormone act?

Answer 0

Directly on GH receptors

Go to the liver to release IgF 1 which helps bones grow

Question 1

Why are girls usually shorter than boys?

Answer 1

Go into puberty earlier therefore reach terminal height earlier

Question 2

Where do GnRH. Euronext arise from?

Answer 2

Olfactory placode and migrate to the hypothalamus along the olfactory tract

Question 3

Name some neuro transmitters that act on the hypothalamus in the HPG axis

Answer 3

Kisspeptin (+)
Neurokinin B (+)
MKRN3 (-)

Question 4

What are the events of puberty in girls?

Answer 4

Breast development
Pubic hair
Growth spurt
Menarche

Question 5

What are the events of puberty in boys?

Answer 5

Testicular and penile enlargement 
Pubic hair 
Voice change 
Growth spurt 
Spermatogenesis

Question 6

What is a common cause of growth problem in children?

Answer 6

Malnutrition

Question 7

What are causes of short stature?

Answer 7

Familial short stature 
Nutritional deficiency 
Chronic disease e.g. Cystic fibrosis 
Endocrine e.g. Hypothyroidism 
Genetic mutation 
Syndrome

Question 8

What are the syndromes associated with short stature?

Answer 8

Down's syndrome 
Turner syndrome 
Foetal alcohol syndrome
Russell silver syndrome 
Noonan syndrome

Question 9

What are the causes of tall stature?

Answer 9

Idiopathic/familial
Obesity related
Endocrine problems e.g. Precocious puberty, hyperthyroidism