Primary lymphoid organs Flashcards
1
Q
What are the primary lymphoid organ?
A
Thymus
bone marrow
2
Q
What is the function of the thymus?
A
Thymocytes mature into T cells
specific receptors are expressed
T cells recognize self from self
3
Q
What receptors are acquired by prothymocytes in the thymus?
A
CD3, CD4, CD8
elimination by apoptosis if dont recognize MHC I, II (positive selection)
if dont recognize self apoptosis (negative selection)
4
Q
What are the secondary lymphoid organs?
A
spleen
lymph nodes
payer patches
tonsils
5
Q
What is the function of the spleen?
A
filters out antigens from blood
white pulp - lymphoid tissue
Red pulp - splenic cord and sinuses (RBCs)
6
Q
What is MALT, GALT and BALT?
A
mucosa associated lymphoid tissue
gut associated lymphoid tissue
bronchus associated lymphoid tissue
