Cella of the adaptive immune system Flashcards
1
Q
What are the cells of the adaptive immune system?
A
T cells (CD4+) B cells
2
Q
What are the different tcells (CD4+)?
A
T helper I
T helper II
3
Q
What is the function of Tcells (CD4+)?
A
recognize processed antigens on the cell surface of DCs in association with MHC Class II molecules.
produce
4
Q
What is the function of T helper 1 cells?
A
secretes IL-2
IFN-gamma
5
Q
What is the function of Thelper 2 cells?
A
aid B cells to produce antibodies
secretes IL-4,5,10
6
Q
What are CD8+ T cells called?
A
cytotoxic T cells (CTL)
7
Q
hat is the function of CTLs?
A
kill target cells directly by inducing apoptosis
8
Q
How is apoptosis induced by CTLs?
A
release perforins at target cell
perforins create transmembrane pores in which granzymes enter
granzymes induce apoptosis
9
Q
What is the function of b cells?
A
produce antibodies that belong to any class such as IgG, Ig E and Ig A. This is called class switching also can present to T cells
