Primary immunodeficiency Flashcards
1
Q
When do you think of primary immunodeficiency?
A
Infections that are SPUR:
- Serious
- Persistent
- Unusual
- Recurrent
2
Q
What are 10 warning signs of PID?
A
3
Q
What is important to know in the history of PID?
A
Infection history
- Site
- Freq
- Need for admission/IV antibiotics
- Microbiology
Immunisation status
Family Hx
- Infections
- Autoimmunity
- Consanguinity
- Neonatal deaths
4
Q
What are the categories of PID?
A
- Antibody (B cells)
- Combined (T cells +)
- Complement - Neonate response
- Phagocyte disorders (e.g. neutrophils)
- Those associated with syndromes
5
Q
How do you analyse the patterns of immunodeficiency by cell?
A
6
Q
What do antibodies do?
A
