Primary Endocrine Organs Flashcards

1
Q

Primary endocrine organs

A

Hypothalamus, Pituitary Gland (anterior and posterior), Pineal Gland, Thyroid gland, Parathyroid Glands, Adrenal Glands and Pancreas

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2
Q

Hypothalamus

A
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3
Q

Hormones of the anterior pituitary gland

A

Growth hormone, prolactin, thyroid-stimulating hormone, adrenocorticotropic hormone, follicle-stimulating hormone and luteinising hormone

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4
Q

Growth hormone

A
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5
Q

Prolactin

A
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6
Q

Tsh

A
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7
Q

ACTH

A
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8
Q

FSH

A
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9
Q

LH

A
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10
Q

Hormones of the posterior pituitary gland

A

Antidiuretuc hormone and oxytocin

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11
Q

Antidiuretuc hormone (ADH)

A

Targets kidneys, promotes water retention increasing blood volume; targets arterioles by stimulating construction which increases BP

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12
Q

Oxytocin (OXT)

A

Targets uterus, stimulates uterine contraction during labour; targets mammary glands, promotes milk ejection during breast feeding

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13
Q

Which hormone does the Pineal gland produce?

A

Produces melatonin

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14
Q

Which organs does melatonin target?

A

Hypothalamus, pancreas, thyroid, pituitary, adrenals and gonads

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15
Q

Principle action of melatonin

A

Major function is to regulate sleep-wake cycle
(low melatonin = wakefulness
high melatonin = sleep)
Other additional functions being identified e.g. inhibiting the reproductive system until sexual maturity

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16
Q

Which hormones does the Thryoid gland produce?

A

Thryoid hormone (thyroid follicles) and calcitonin (parafollicular cells)

17
Q

Thryoid hormone target and action

A

General target. Principle actions include: regulating tissue growth and development, promoting carbohydrate oxidation and controlling production of catecholamines.

18
Q

Calcitonin

A

Targets bike and kidneys.
Decreases blood calcium concentration by: increasing deposition in bone and promoting calcium excretion by kidnevs

19
Q

Types of thyroid hormones

A

• Tetra-iodothyronine (thyroxine) (Ta);
contains four iodine atoms
• Triiodothyronine (T3);
contains three iodine atoms

20
Q

Which hormone does the parathyroid glands produce and what is its target and principle action?

A

Parathyroid hormone. Targets bone and kidneys. Increases blood calcium concentration by:
stimulating breakdown of bone, increasing calcium reabsorption by the kidneys, increasing the synthesis of calcitriol by the kidneys

21
Q

What is the relationship between Calcitonin and PTH?

A

They are antagonists

22
Q

Which hormones does the adrenal glands produce?

A

Mineralocorticoids, glucocorticoids, androgens and catecholamines

23
Q

Mineralocorticoids
(e.g. aldosterone)

A

Targets kidneys. Promotes sodium and water retention. Promotes loss of potassium and hydrogen ions in urine.

24
Q

Glucocorticoids
(e.g. cortisone, cortisol)

A

General target. Increases blood glucose, HR and BP (in response to stress). Maintains basal cell metabolism. Suppresses the immune system.

25
Q

Androgens

A

Targets gonads and regulates sex hormones.

26
Q

Catecholamines (e.g. adrenaline, noradrenaline)

A

Target is general. Mediates flight-or-flight response (i.e. increases heart rate, blood pressure, vasodilation and blood glucose)

27
Q

Which hormones are hormones of the adrenal cortex?

A

Mineralocorticoids, glucocorticoids and gonadocorticoids (androgens)

28
Q

Cateholamines are hormones of..?

A

The adrenal medulla

29
Q

Which hormones does the pancreas produce?

A

Insulin, glucagon, somatostatin and pancreatic polypeptide

30
Q

Insulin
(beta cells)

A

Targets muscle, adipose tissue and liver.
Decreases blood glucose levels by stimulating uptake of glucose and promoting glycogen formation

31
Q

Glucagon (alpha cells)

A

Targets liver. Increases blood glucose levels by stimulating glycogen breakdown, increasing gluconeogenesis and inhibiting glycogen formation.

32
Q

Somatostatin (delta cells)

A

Targets pancreas and hypothalamus. Inhibits release of glucagon and insulin and regulates the pituitary gland.

33
Q

Pancreatic polypeptide
(PP cells)

A

General target, regulates feelings of hunger and satiety

34
Q

What is the relationship between insulin and glucagon?

A

They are antagonists