Primary and Secondary Prevention of Cervical Cancer

Question 1

Spectrum of cervical dysplasia

Answer 1

1. Cervical intraepithelial neoplasia (CIN) I- koilocytic atypia
2. CIN II- progressive atypia in all layers of the epithelium
3. CIN III- carcinoma in situ; diffuse atypia and loss of maturation

Question 2

Characteristics of koilocytic change

Answer 2

1. Larger nuclei
2. Denser staining nuclei
3. Perinuclar halo
4. Irregular nuclear shape

Question 3

Cervical screening timeline

Answer 3

If low risk: every 2 years for women between 21 and 29

every 3 years for women older than 30 years