Preventative Peds Flashcards

1
Q

Is the inactivated influenza vaccine (IIV) safe to administer during pregnancy?

A

Answer
Yes
Explanation
IIV is recommended and considered safe during any stage of pregnancy. Pregnancy increases the risk of complications and hospitalization from influenza. Pregnancy is a contraindication to administration of all live-virus vaccines, including the live attenuated influenza vaccine. IIV is not a live-virus vaccine and is only rarely associated with major systemic reactions. Mild systemic symptoms, such as fever, nausea, lethargy, headache, myalgia, and chills, can occur

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2
Q

An adolescent receives MMR and experiences joint pain 10 days after the vaccination.

What component of the vaccine is likely responsible for this?

A

Rubella
Explanation
Adverse events of MMR include:
Tenderness/warmth at the injection site (common)
Fever to 103.0° F ([39.4° C ] in 5–15% of recipients)
Febrile seizures (in 1:3000–3400 recipients)
Transient rash occurring 6–12 days after MMR (in 5% of recipients)
Transient thrombocytopenia (in 1:22,000–40,000 recipients)
In adolescents, joint pain (arthralgia [secondary to the rubella component]) 7–21 days after MMR (in up to 25% of recipients); transient arthritis is reported in up to 10% of recipients

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3
Q

What is the cut-off age for giving a DTaP?

A

Answer
< 7 years of age
Explanation
Do not give DTaP to children ≥ 7 years of age. After that, Tdap is recommended at 11–12 years of age, followed by a Td or Tdap booster every 10 years thereafter. Children 7–10 years of age who have not completed their primary immunization schedule should receive a single dose of Tdap; if additional tetanus and diphtheria toxoid doses are required, use Td or Tdap. Children who receive Tdap at 7 through 9 years of age may receive the standard Tdap booster at 11 or 12 years of age. Children who received Tdap at 10 years of age do not require the 11–12 year old dose

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4
Q

Within hours of his 1st DTaP vaccination, a 2-month-old boy became irritable and had a febrile seizure with a temperature of 104.8°F (40.5°C).

Do these reactions represent an absolute contraindication to additional doses of DTaP?

A

No
Explanation
Absolute contraindications to additional doses of DTaP include a history of encephalopathy (e.g., prolonged seizures, coma, altered mental status) within 7 days of dosing or an immediate anaphylactic reaction with a previous dose. Precautions to additional doses of DTaP include Guillain-Barré syndrome within 6 weeks after receiving a tetanus toxoid-containing vaccine; moderate or severe acute illness with or without a fever (until resolution); a history of an evolving or progressive neurologic disorder (delay vaccination until neurologic status is stable or the disease process is clarified). More serious and rare adverse effects following DTaP include a hypotonic-hyporesponsive episode; temperature > 104.8°F (40.4°C); febrile seizures; brachial neuritis; and entire limb swelling following the 4th or 5th vaccine in the series.

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5
Q

A 10-year-old’s permanent tooth is knocked out while playing in the back yard. The mother calls you and asks you what to do. She is not able to reimplant the tooth because the child is uncooperative. You get in touch with a dentist on call, who will meet them soon at his office.

You tell her to bring the tooth in what common household liquid?

A

Cold milk
Explanation
If the tooth cannot be reimplanted, it should ideally be kept in Hank’s Balanced Salt Solution (HBSS) or Save-A-Tooth solution. If these are not available, then cold milk, followed by saliva, physiologic saline solution, or any available isotonic solution is best. Survival of an avulsed permanent tooth is inversely related to the amount of time spent out of the oral cavity; survival rates are close to zero after 1–2 hours. Avulsed primary teeth should not be reimplanted because of the risk of injury to the developing tooth bud.

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6
Q

What is the only live vaccine given before 12 months of age?

A

Answer
Rotavirus vaccine
Explanation
All other vaccines given before 12 months of age are either killed or recombinant. RV5 (RotaTeq) is orally administered at 2, 4, and 6 months of age; RV1 (Rotarix) is orally administered at 2 and 4 months of age. The 1st dose of either vaccine must be given at 6 weeks through 14 weeks, 6 days of age. The minimum interval between doses is 4 weeks; all doses of rotavirus vaccine must be administered by 8 months, 0 days of age.

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7
Q

A 24-month-old boy is taken into emergency protective custody due to medical neglect. His immunization record states that he received hepatitis B (HepB) vaccine at birth; at 2 months of age he received a combination vaccine (DTaP-HepB-IPV), Hib, and PCV13.

Do one or more of the vaccine series need to be restarted in this patient because he was last vaccinated > 1 year ago?

A

Answer
No
Explanation
A vaccine series does not need to be restarted, regardless of the time that has elapsed between doses. Therefore, this patient has already received 2 doses of HepB and 1 dose each of DTaP (diphtheria, tetanus, acellular pertussis), IPV (inactivated poliovirus), Hib (Haemophilus influenzae Type b), and PCV13 (13-valent pneumococcal conjugate vaccine). The number of catch-up doses required and the minimal interval between doses varies by vaccine and the age of the patient at the time catch-up is initiated. Give this child:
1 dose each of HepB, Hib, and PCV13,
4 doses of DTaP (1 dose now, another dose in 4 weeks, another in 6 months, and a final dose at 4–6 years of age), and
3 doses of IPV (1 dose now, another dose in 4 weeks, and a final dose at 4–6 years of age).

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8
Q

All infants should have a hearing screen by no later than what age?

A

1 month of age
Explanation
Universal hearing screening should ideally be completed before newborns are discharged from the hospital but no later than 1 month of age in all infants. Screening is usually performed with auditory brainstem response testing (ABR), which measures how CN 8 responds to sound. You can also use otoacoustic emissions analysis (OAE), which measures sound waves made in the inner ear as an echo in response to sound. The AAP Early Hearing Detection and Intervention Program recommends screening by no later than 1 month of age, diagnosis of hearing loss by 3 months of age, and entry into early intervention services by 6 months of age.

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9
Q

What are the first teeth to typically emerge?

A

Mandibular central incisors
Explanation
Tooth eruption rates and locations may vary greatly, but the first tooth typically erupts by 5–10 months of age. The lower anterior teeth (mandibular incisors) emerge first, followed by the upper opposing teeth (maxillary incisors), the upper lateral incisors, and then the lower lateral incisors. The first molars, cuspids (canines), and finally the second molars then follow. There are 20 baby teeth, all of which have generally erupted by 30–33 months of age. Girls tend to develop their teeth earlier than do boys, and Black children earlier than White children.

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10
Q

At what age(s) is the meningococcal conjugate vaccine (MCV4) recommended for individuals without a medical condition that places them at increased risk for meningococcal disease?

A

11–12 years of age; booster dose at 16 years of age
Explanation
MCV4 vaccines (Menactra and Menveo) each contain serotypes A, C, Y, and W-135. A single dose of either vaccine is recommended at 11–12 years of age, with a booster at 16 years of age to enhance protection during the period of highest risk (i.e., patients 18–23 years of age—especially college freshmen). Adolescents who receive their 1st dose at 13–15 years of age should receive a booster dose at 16–18 years of age; 1 dose should be administered to previously unvaccinated college freshmen prior to school entry. Menactra and Menveo are also licensed for high-risk infants and children but with different administration schedules.

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11
Q

During blood pressure (BP) measurement, what is the recommended position of the patient and appropriate cuff size to minimize the risk of an inaccurate reading?

A

Seated with legs uncrossed; cuff covers ≥ 2/3 length of the upper right arm and wraps ≥ 3/4 of the arm circumference
Explanation
BP is best measured with the child sitting, the right arm held at heart level. The bladder of the blood pressure cuff should cover at least 2/3 the length of the upper arm and wrap around at least 3/4 of the arm circumference (thus, the cuff itself often overlaps). A cuff that is too small will yield an inaccurate and artificially elevated reading. The cuff should be inflated to 20 mmHg above the loss of the radial pulse and then deflated at 2–3 mmHg/second. The 1st sound heard is a tapping sound, known as Korotkoff sound 1, which is recorded as the systolic blood pressure. The level at which all sound disappears is Korotkoff sound 5, which is the measured diastolic pressure.

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12
Q

At what age(s) is fasting or nonfasting screening, with total and high-density lipoprotein cholesterol (HDL-C) levels, universally recommended for children and adolescents?

A

Once between 9 and 11 years of age and once between 17 and 21 years of age
Explanation
The AAP recommends fasting or nonfasting screening for hyperlipidemia in all children and adolescents in these age groups, regardless of risk factors. If non-HDL-C ≥ 145 mg/dL and/or HDL-C < 40 mg/dL, then get 2 fasting lipid panels and average the results. In the absence of risk factors, routine lipid screening is not recommended in children 2–8 years of age or 12–16 years of age.

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13
Q

According to the 2020 AAP Bright Futures guidelines, at what age should routine screening for anemia be performed in all children?

A

Answer
9-12 months of age
Explanation
The Bright Futures/AAP guidelines recommend routine hemoglobin testing in children 9–12 months of age. The guidelines also recommend a schedule of ongoing risk assessments for iron deficiency anemia in all infants at all well-child evaluations from 4–36 months of age, and annually thereafter throughout childhood and adolescence. More frequent testing is recommended for children identified as high risk (e.g., premature, low birth weight, exclusively breastfed without iron supplementation after 4–6 months of age, history of poverty and food insecurity, strict vegan diets, eating disorders, malabsorption disorders).

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14
Q

What is the only vaccine currently recommended at birth?

A

Hepatitis B
Explanation
Administer single-antigen HepB vaccine to all newborns within 24 hours of birth. Administer a 2nd dose at 1–2 months of age (minimum interval of 4 weeks). Administer the 3rd dose at 6–18 months of age. The 3rd dose must be administered at least 8 weeks after the 2nd dose and at least 16 weeks after the 1st dose. The 3rd dose in the series should be administered no earlier than 24 weeks of age. Administration of 4 doses is acceptable when a combination vaccine containing HepB is used after the birth dose.

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15
Q

At what age should routine blood pressure (BP) screening begin in healthy children with no coexisting medical condition predisposing to hypertension (HTN)?

A

3 years of age
Explanation
BP should be measured in children < 3 years of age with a coexisting medical condition predisposing to HTN (e.g., history of prematurity, very low birth weight, neonatal complications requiring intensive care/umbilical lines, congenital heart disease, recurrent UTIs, chronic renal disease or renal malformations, family history of congenital renal disease). Normal BP is defined as both systolic and diastolic blood pressure < 90th percentile for age (< 120/< 80 mmHg in adolescents ≥ 13 years of age).

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16
Q

A child comes in for his routine immunization. You learn that the mother is pregnant, and the child is still breastfeeding.

What vaccines are contraindicated in this child today?

A

Answer
None
Explanation
There are no contraindications to immunizing a child whose mother is pregnant and/or breastfeeding. All routine vaccines may be given to the child today.

17
Q

According to the AAP/Bright Futures 2021 Recommendations, at what age should you begin to routinely assess the use of tobacco, alcohol, and drugs?

A

11–12 years of age
Explanation
With respect to health supervision, the well-child visit is one of the pediatrician’s most important tools. Always provide counselling and guidance at each well-child visit. In the early visits, most counseling revolves around feeding, injury prevention, developmental/behavioral issues, daily care, immunizations, and medical issues. As the child grows, a range of age-appropriate topics, from bicycle helmets and gun safety to sexual activity and tobacco/substance use becomes the focus of counseling. Be sure you know these topics and the recommended ages to discuss them at a well-child visit.

18
Q

In what population and at what age(s) is hepatitis A vaccine routinely recommended?

A

Answer
Universally recommended at 12–23 months of age; 2nd dose ≥ 6 months after the 1st
Explanation
Unvaccinated persons through 18 years should complete a 2-dose series (minimum interval: 6 months). Virtually all those completing the series develop protective levels of antibody to Hepatitis A virus (anti-HAV). Adverse reactions are mild and include local pain and induration at the injection site. No serious adverse events to HepA vaccine have been reported.

19
Q

Can someone with egg allergy receive MMR?

A

Answer
Yes
Explanation
Although the MMR vaccine is produced in chicken embryo cell culture, the vaccine does not contain significant amounts of cross-reacting egg proteins. Therefore, severe egg allergy is not a contraindication to vaccination with MMR or any of its components. Both MMR and MMRV can be safely administered to children with egg allergy without prior skin testing or special protocols.

20
Q

What is the best way to reduce head and facial injuries while riding a bike?

A

Wear a helmet
Explanation
Prevention of bicycle injuries is an important topic to discuss with all age groups. Head injuries, which account for the majority of bicycle-related deaths and hospital admissions, can often be avoided with proper precautions and consistent use of bicycle helmets. Proper-fitting bicycle helmets should be worn at all ages. Adolescents are at increased risk of bicycle injury and death and should be strongly encouraged to wear bicycle helmets every time they ride.

21
Q

A 2½-year-old boy who underwent emergent splenectomy at 16 months of age following an automobile accident has received a total of 4 doses of PCV13. His last dose was at 15 months of age.

What are the recommendations for PPSV23 in this patient?

A

Answer
A single dose at this visit, a 2nd dose in 5 years
Explanation
After completing a 4-dose series of PCV13 (recommended at 2, 4, 6, and 12–15 months of age), children at risk for invasive pneumococcal infections should receive a single dose of PPSV23 at 24 months of age. PPSV23 is administered with a minimum interval of 8 weeks following the last dose of PCV13. A 2nd dose of PPSV23 is recommended 5 years after the 1st dose in children with sickle cell disease or other hemoglobinopathies, functional or anatomic asplenia, and HIV infection or other immunodeficiency disorder. No more than a total of 2 lifetime PPSV23 doses should be administered.

22
Q

A 17-year-old boy with a cochlear implant presents for evaluation. You note that he received PCV7 and PPSV23 three years ago following his implant.

What pneumococcal vaccine, if any, should he receive today?

A

Answer
PCV13
Explanation
A single dose of PCV13 may be given to children 6–18 years of age who have not received PCV13 previously and are at increased risk of invasive pneumococcal disease because of, for example, anatomic or functional asplenia, sickle cell disease, HIV, or cochlear implant, regardless of whether they have previously received PCV7 or PPSV23. Administer this dose at least 8 weeks after the most recent dose of PPSV23. PPSV23 does not need to be repeated in 5 years in a child with a cochlear implant; it should be repeated 5 years after the 1st dose in a child who has HIV, anatomical or functional asplenia, or is immunocompromised.

23
Q

The mother of an 18-month-old boy is concerned that his “eyes sometimes look crossed.”

Name 2 tests that may be used in this age group to evaluate for strabismus.

A

Corneal light reflex test; unilateral cover test
Explanation
In toddlers and preschool age children, use the corneal light reflex test to confirm that the position of the corneal reflection is the same in both eyes. Perform the test by holding a light about 3 feet from both eyes. Displacement of the corneal light reflection in 1 eye suggests strabismus. Perform the unilateral cover test by covering and uncovering each eye while the child is looking straight ahead. Results are consistent with strabismus if there is movement in the uncovered eye when the opposite eye is covered vs. uncovered.

24
Q

A 2-year-old with a history of hives with no associated systemic symptoms following egg ingestion has never received an influenza vaccine.

What are the recommendations for influenza vaccination in this patient?

A

2 doses of vaccine, separated by at least 4 weeks; 1 dose annually thereafter
Explanation
For children < 9 years of age who have never been vaccinated, 2 doses, ≥ 4 weeks apart, of inactivated influenza vaccine (IIV) are indicated. Thereafter, 1 annual vaccine is recommended. IIV may be administered to infants as young as 6 months of age. Although most IIV vaccines are produced in eggs, the vaccine is well tolerated by most recipients with egg allergy; skin testing or a 2-step graded challenge is no longer recommended in egg-allergic patients. The most common adverse events after IIV administration are local injection site pain; tenderness; fever; and mild systemic symptoms such as nausea, lethargy, headache, myalgia, and chills. Live attenuated influenza vaccine (LAIV) is an alternative to IIV in healthy children ≥ 2 years of age without any underlying chronic medical condition. The presence of egg allergy in an individual is not a contraindication to receiving LAIV. As with IIV, for children < 9 years of age who have never been vaccinated, 2 doses, ≥ 4 weeks apart, of LAIV are indicated.

25
Q

A child has not had any immunizations.

Assuming that the child is immunocompetent, what is the cut-off age for receiving a Haemophilus influenzae Type b (Hib) vaccine?

A

Answer
≥ 5 years of age
Explanation
Do not immunize children ≥ 5 years of age because they are at much lower risk for serious sequelae. One dose of Hib is recommended for those ≥ 5 years of age if they are considered high risk (e.g., functional/anatomic asplenia, HIV, leukemia, immunocompromised). For children 12–59 months of age with an underlying condition predisposing to Hib disease who are not immunized, 2 doses of Hib, separated by 2 months, are recommended.

26
Q

A 3-month-old with severe combined immunodeficiency (SCID) presents for his first set of immunizations.

What routinely recommended immunization is contraindicated in this patient?

A

Rotavirus vaccine
Explanation
Rotavirus vaccine is a live attenuated virus vaccine and is contraindicated in children with SCID because it can lead to severe diarrhea and prolonged shedding of the vaccine virus.

27
Q

What are the 5 subcutaneously administered vaccines?

A

Answer
MMR, varicella, MMRV, PPSV23, and IPV
Explanation
All the rest are IM except for rotavirus, which is given orally, and the live attenuated influenza nasal vaccine. The IPV (inactivated poliovirus) vaccine and PPSV23 (23-valent pneumococcal polysaccharides vaccine) may be given either IM or subcutaneously.

28
Q

A previously unimmunized child presents at 4 months of age.

It is now too late to administer which routinely recommended vaccine?

A

Rotavirus vaccine
Explanation
If a child is not given their first rotavirus vaccine by 14 weeks 6 days of age, then the CDC recommends not to give it at all. Also, do not administer the final dose if the child is > 8 months 0 days of age.

29
Q

At what age does the American Academy of Pediatric Dentistry (AAPD) recommend that children begin seeing a dentist?

A

Answer
The AAPD recommends a first dental appointment at or near 12 months of age.
Explanation
All children should receive a dental referral at or near their 1st birthday. However, if dental providers in the area are unwilling to see children who are younger than 3 years of age, you may continue to provide preventive dental care and counseling for infants and younger children who are at low risk of developing dental disease and have no abnormalities on screening examination.

30
Q

A preterm girl born at 26 weeks of gestation is now 2 months of chronologic age and remains in the NICU. She is clinically stable and has steady growth. She will likely stay in the NICU for several more weeks to gain additional weight.

List the vaccinations she may receive prior to discharge from the NICU.

A

Hepatitis B (HepB) vaccine; DTaP; PCV13; Hib; IPV
Explanation
All immunizations recommended at 2 months of age may be given simultaneously to this preterm infant except for the live oral rotavirus vaccine. Defer this until discharge from the NICU to prevent nosocomial spread of the vaccine virus. Use combination vaccines in infants ≥ 6 weeks of age to reduce the number of injections of the inactivated vaccines (HepB, DTaP, PCV13, Hib, IPV). If decreased muscle mass/limited injection sites make it difficult to administer 3 or 4 injections simultaneously, give the vaccines at 2-week intervals to avoid superimposing local reactions.

31
Q

Varicella vaccine is contraindicated in children or adolescents receiving what dose—and for how long—of systemic corticosteroids?

A

≥ 2 mg/kg/day (or 20 mg/day if > 10 kg) for ≥ 14 days
Explanation
Varicella (or MMR/MMRV) vaccine should not be administered to children or adolescents receiving high-dose systemic corticosteroids—defined as ≥ 2 mg/kg/day (or 20 mg/day if > 10 kg) for 14 days or more. The recommended interval between discontinuation of high-dose corticosteroid therapy and immunization with varicella (or MMR/ MMRV) vaccine is at least 1 month. Inhaled, topical, and nasal corticosteroid therapies are not a contraindication to administering varicella (or MMR/MMRV) vaccine.

32
Q

What temperature should the hot water heater be set at in the typical home?

A

Answer
≤ 120.0° F (48.8° C)
Explanation
Other important child safety items you should review with parents:
Smoke and carbon monoxide detectors installed at home
Cabinet locks and plastic “plugs” for electrical receptacles
Stair safety/dangers of walkers
Poison prevention
Firearm safety
Choking prevention
Drowning prevention

33
Q

Administration of a pertussis-containing vaccine is contraindicated in a 15-month-old boy with developmental delay of unknown etiology associated with a poorly controlled seizure disorder. He has never received a pertussis-tetanus-diphtheria–containing vaccine.

What are the recommendations for immunization against tetanus and diphtheria in this patient?

A

Answer
Administer 2 doses of DT 1–2 months apart; 3rd dose in 6–12 months; 4th dose at 4–6 years of age.
Explanation
This schedule is recommended for previously unimmunized children 1–6 years of age with a medical contraindication to a pertussis-containing vaccine. The 4th dose is recommended at 4–6 years of age unless the 3rd dose is administered after the 4th birthday. Td, rather than DT, is indicated at ≥ 7 years of age.

34
Q

A child is to have a PPD and MMR today.

Can you give both today at the same office visit?

A

Yes
Explanation
The problem comes if you give the MMR (measles, mumps, rubella) today and do not give the PPD (purified protein derivative) today, then you must wait 4–6 weeks before placing the PPD. This is because the measles vaccine can temporarily suppress tuberculin reactivity. This suppression is not immediate, however, so it is fine to give both today. Tuberculin skin testing can also be performed any time before the day of immunization with MMR.

35
Q

At what ages do the majority of state and federal screening programs and the AAP recommend universal screening for lead?

A

Approximately 12 and 24 months of age
Explanation
AAP/Bright Futures guidelines recommend that screening for lead poisoning follow federal, state, and local laws, which typically recommend universal screening at approximately 1 and 2 years of age. Detectable blood lead levels are associated with irreversible neurocognitive deficits. A lower limit for lead toxicity has not been established. Because there is no known safe threshold for lead exposure, action should be taken in all children with blood lead levels ≥ 3.5 μg/dL (e.g., environmental assessment and eradication of lead).

36
Q

A 4-year-old boy with sickle cell disease has never received an influenza vaccine.

What are the recommendations for the influenza vaccine in this patient?

A

2 doses of inactivated influenza vaccine (IIV), separated by ≥ 4 weeks; 1 annual dose thereafter
Explanation
Influenza vaccination is indicated for all children ≥ 6 months of age. For children < 9 years of age who have never been vaccinated, 2 doses of vaccine, separated by ≥ 4 weeks, are required to achieve adequate antibody levels. Thereafter, 1 annual vaccine is recommended. Annual vaccination is important due to antigenic drift, which occurs continuously and results in new strains of influenza viruses. The IIV, rather than the live attenuated influenza vaccine, is recommended in any patient at high risk for complications from influenza. High-risk groups include those with chronic pulmonary or hemodynamically significant cardiac disease, functional asplenia (e.g., sickle cell disease or other hemoglobinopathy), anatomic asplenia, chronic renal disease, or metabolic disease (including diabetes mellitus).

37
Q

When should infants and toddlers be switched from a rear-facing car safety seat to a forward-facing car safety seat?

A

After having reached the highest weight or height allowed by the seat’s manufacturer.
Explanation
Infants and toddlers should be placed in a rear-facing car safety seat for as long as possible, until they reach the highest weight or height allowed by the seat’s manufacturer. Most car safety seats have limits that will allow children to ride rear-facing for 2 years or more. Therefore, recommendations have been modified to no longer include specific age milestones. Once they are facing forward, children should use a forward-facing car safety seat with a harness until they reach the height and weight limits for their seats; most seats can accommodate children up to at least 65 pounds.

If a premature infant needs more head support, place body blanket rolls on both sides of the infant. Use only the head support system that comes with the car safety seat. If a premature infant’s head still falls forward when the rear-facing car seat is at ∼ 45°, place a tightly rolled blanket or pool noodle under the car safety seat to maintain the recommended 45° angle.