preventative care 2 Flashcards

1
Q

groups of anthelmentics and their levels of resistence

A

1-BZ- Extensive resistance

2-LV- Resistance common

3-ML- Resistance evident

emerging resistnce in-
4-AD
5-SI

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2
Q

Environmental impact of anthelmintic use

A

Faecal excretion of anthelmintic can impact on non-target species (e.g Dung beetle) and soil ecosystem- BZ and PYR < macrocyclic lactones (MLs) where 90% excreted within 4 days but IVM persists for up to 40 days in faeces.

Label information identifies Environmental Risk Assessment (ERA)

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3
Q

sheep Gastrointestinal nematodes- Abomasum

A

Haemonchus contortus
Teladorsagia circumcincta
Trichostrongylus axei

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4
Q

sheep Gastrointestinal nematodes- Small Intestine

A

Nematodirus spp
Trichostrongylus
spp
Cooperia spp

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5
Q

sheep Gastrointestinal nematodes- Large Intestine

A

Chabertia spp
Oesophagostomum spp
Trichuris spp

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6
Q

control of parasites on farm- 1. Intervention - pre-parasitic stages

A

Need sound knowledge of epidemiology- l1-l2-l3 (often in pasture)

Assess the risk of grazing certain pastures:
Low risk pastures
High risk pastures

Risk posed by pasture-
Clean pasture – not grazed by sheep for the previous 12 months
Safe pasture – used the previous year but safe by beginning of June

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7
Q

control of parasites on farm- 2. Intervention - parasitic stages in host

A

l4->l5

Anthelmintics
Breeding for resistance or resilience- Breed from low egg shedding stock.
Breed from animals that retain growth potential even in presence of infection

Optimise nutritional status of ewes/lambs

Vaccines?- Vaccine available for Haemonchus contortus (in Australia and S Africa only)
And still in development for T. circumcincta. Unlikely to work in isolation.

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8
Q

control of parasites on farm- forecasting

A

NADIS – National Animal Disease Information Service
www.nadis.org.uk/

Nematodirus battus
Fasciola hepatica

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9
Q

control of parasites on farm- GAME

A

Assess risk to your flock

G-General health and genetics- Optimise health status of ewes and lambs
A- Avoidance
Graze high-risk animals (lambs) on low risk pastures
Disease forecasting
Don’t ‘buy in’ resistant parasites

M- Monitoring
Measure daily live weight gain or FEC

E- Effective and efficacious treatment

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10
Q

cattle nematodes

A

Ostertagia ostertagi
Cooperia oncophora
Lungworm – Dictyocaulus viviparus

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11
Q

cattle trematodes

A

Fasciola hepatica

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12
Q

endoparasite control in cattle

A

Prevent clinical disease
Prevent sub-clinical losses
Allow immunity to develop

options-
grazing strategies
strategic seasonal anthehlmentic use to misimise pasutre contamination
tageted treatment of the whole group based on fec and weight monitoring
targeted treatment of individiual bease on stock health and growth rates
housing treatments

risk assesmemnnet-
Risk posed by pasture
Age group of animal
Health status of animal
Disease forecasting e.g fluke

Diagnostics-
Lungworm (Vaccination with Huskvac)
Ostertagia FEC, Ab detection ELISA
Fluke – coproantigen, Ab detection, FEC

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13
Q

horse nematodes

A

Cyathostomin spp
Parascaris equorum
Cestodes:
Tapeworm Anoplocephala perfoliata

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14
Q

reducing risk of parasitisim in horses posed by pasture

A

Appropriate stocking density
Pasture management
Faecal collection – at least twice a week
Dung heaps separate from grazing areas
Pasture rotation
Grazing with ruminants

poo picking
rotate pature
be aware of parasites that overwinter
faeces at edge of feild pose risk- larvae can spread

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15
Q

diagnostics for horse endoparasites

A

Strongyles:
FEC – centrifugation flotation (60% sensitive)

Tapeworms:
EquiSal – saliva-based ELISA
Diagnosteq (blood) Ab detection tapeworm ELISA
Herd level testing of horses, particularly on studs

Cyathostomin ELISA
Complex interpretation
Detects all parasite stages not just adult stages
In low risk horses not currently recommended until further validation has occurred.

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16
Q

Sustainable control principles for anthelmintic use.

A

Sustainable, responsible and practical strategies for anthelmintic use.

Always make sure any treatment you give is fully effective (FECRT).
Administer correct dose
Dispose of appropriately

Target drug treatments.

Reduce reliance on anthelmintics using management options and monitoring where possible.

Avoid bringing in resista
nt worms and/or other parasites by following a robust quarantine routine.

Medicines licensed for farmed livestock since 2005 undergo an Environmental Risk Assessment (ERA), reviewed by the Veterinary Medicines Directorate (VMD

17
Q

Anthelmintic prescribers

A

POM-VPS – equine and ruminant sector
POM-V – Companion animal sector

18
Q

Anthelmintic in companion animals

A

No cases of drug resistance reported for endoparasites in Europe- true? found in america

Drug treatment driven by some basic risk assessment, but no diagnostics.

Anthelmintics often combined with ectoparasite (flea) treatment. ? Need for regular (e.g monthly de-worming?

New guidance as of Sept 2023
https://www.rcvs.org.uk/setting-standards/advice-and-guidance/under-care-new-guidance/
‘anti-parasitic POM-V’ changes