Pressors/Inotropes:

Question 1

Pressors/Inotropes: Peds

Norepinephrine

Answer 1

0.1-2 mcg/kg/min
α&raquo_space;β; distributive, hypovolemic

Question 2

Pressors/Inotropes: Adult

Norepinephrine

Answer 2

5-20 mcg/min

α&raquo_space; β; distributive, hypovolemic

Question 3

Pressors/Inotropes:

Dobutamine

Answer 3

5-20mcg/kg/min; max 40mcg/kg/min
β1 > β2&raquo_space; α1; cardiogenic

Question 4

Pressors/Inotropes:

Dopamine

Answer 4

5-20mcg/kg/min, increase by 1-4mcg/kg/min at 10min intervals (max 50mcg/kg/min)
(dopamine receptors > α > β; all types)

Question 5

Pressors/Inotropes: Peds

Epineph

Answer 5

0.1-1mcg/kg/min, titrate up to 5mcg/kg/min

β&raquo_space; α; all types

Question 6

Pressors/Inotropes: Adult

Epineph

Answer 6

7-30mcg/min (no weight), titrate to response

β&raquo_space; α; all types

Question 7

Pressors/Inotropes:

Milrinone (PDE3 inhibitor):

Answer 7

50mcg/kg over 15mins loading then 0.25-0.75mcg/kg/min

↑ cAMP →↑ contractility, ↓PVR; cardiogenic

Question 8

Pressors/Inotropes:

Phenylephrine

Answer 8

0.1-0.5mcg/kg/min

α1 > α2&raquo_space;> β; distributive, hypovolemic

Question 9

Pressors/Inotropes:

Vasopressin

Answer 9

0.01-0.04 units/min (no weight)

vasopressin receptors: ↑BP > ↑HR; distributive