Preservation, storage and transportation of blood Flashcards
1
Q
what is ACD made of
A
trisodium citrate
citric acid
dextrose
distilled water
2
Q
for each 100 ml of blood, how much ACD solution is sufficient?
A
15 mL
3
Q
mechanism of action for citrate
A
- prevents coagulation
2. retards glycolysis
4
Q
mechanism of action for dextrose
A
- improves red cell viability
- provides energy for ATP synthesis
- decreases rate of hydrolysis of phosphorus
5
Q
mechanism of action for citric acid
A
prevents glucose caramelization during autoclaving
provides optimal pH with citrate for red cells
6
Q
what does ACD solution do
A
preserves ATP level
helps maintain red cells shape
prevents hemolysis
maintains pH
7
Q
shelf life of whole blood/red cells in ACD
A
21 days
8
Q
heparin mechanism
A
inhibits coagulation
inactivates fXa, IXa, XIa, plasmin
