Prescription review Flashcards

1
Q

what is the PReSCRIBER mneumonic?

A
  • Patient details
  • Reaction (i.e. allergy + reaction to medication)
  • Sign the front of the chart
  • Contraindications
  • Route of drug
  • Intravenous fluids - assess if needed
  • Blood clot prophylaxis - assess if needed, what to give
  • Anti-Emetic - assess if needed
  • Pain Relief - assess if needed
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2
Q

What to check for patient details?

A

needs to have 3 e.g. name, DOB and hospital number

can use patient sticker with all of this on

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3
Q

What are the main groups of contraindications to consider?

A
  1. anti-platelets + anti-coagulants not to be given to patients who are actively bleeding, suspected of bleeding or at high risk of bleeding
  2. SE of steroids (STEROIDS) - Stomach ulcer, Thin skin, oEdema, Right + L HF, Osteoporosis, Infection (incl. Candida), Diabetes, cushing’s Syndrome
  3. safety of using NSAID - No urine, Systolic dysfunction (HF), Asthma, Indigestion, Dyscarsia (clotting abnormal)
  4. broad SE of anti-HTN - hypotension, bradycardia (beta-blocker, CCB), electrolyte disturbance (ACEi, diuretics)
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4
Q

What are the SE of steroids?

A

STEROIDS

  • Stomach ulcers
  • Thin skin
  • oEdema
  • Right and left heart failure
  • Osteopororsis
  • Infection incl. candid
  • Diabetes (usually ↑ BM)
  • Cushing’s Syndrome
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5
Q

What factors to consider if NSAID is safe to prescribe?

A

NSAID

  • No urine e.g. renal failure
  • Systolic dysfunction e.g. HR
  • Asthma
  • Indigestion
  • Dyscrasia (clotting abnormality)
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6
Q

SE of anti-HTN

A
  • Hypotension for all (earliest Sx, postural hypotension)
  • Beta-blocker + CCB → bradycardia
  • ACEi + diuretics → electrolyte disturbance
  • ACEi → dry cough
  • Beta-blockers → wheeze in asthmatics, worsening acute HF (useful in chronic)
  • CCD → peripheral oedema, flushing
  • Diuretics → renal failure
  • Thiazide (bendroflumethiazide) → gout
  • K+ sparing (spironolactone) → gynaecomastia
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7
Q

what considerations for medication routes are there?

A
  • vomiting - anti-emetic given SC/IM/IV, if only short period of vomiting don’t convert all other
  • degree of clinical well/unwell - i.e. IV Abx for very unwell
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8
Q

When should 0.9% NaCl not be used?

What should be given instead?

A

Hypernatraemia or hypoglycaemia → 5% dextrose instead

Ascites → human albumin solution instead

Shocked from bleeding → blood transfusion, crystalloid until blood available

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9
Q

what indications for fluids?

A
  • acutely unwell or volume depleted
  • maintenance fluids in NBM patients or with very low oral intake
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10
Q

what fluids for hypernatraemia or hypoglycaemia?

A

5% dextrose

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11
Q

what fluids for ascites patients?

A

human albumin solution to maintain oncotic pressure

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12
Q

what fluids in shocked pt secondary to haemorrhage?

A

blood transfusion

crystalloid (normal saline) until blood available

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13
Q

what is the maximum amount of IV potassium?

A

do not give more than 10 mmol/hour

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14
Q

considerations for maintenance fluids?

A
  • General rule - 3L/24hrs for adults, 2L/24hrs for elderly
  • Electrolytes - 1L 0.9% saline and 2L of 5% dextrose (1 salty, 2 sweet)
  • Normal potassium require 40mmol KCl per day → put 20 mmol in 2 bags
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15
Q

rough maintenance amounts for adults + elderly?

A
  • adults = 3L
  • elderly = 2 L

over 24 hours

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16
Q

attaining maintenance electrolytes from IV fluids

A
  • 1 salt + 2 sweet - 1L NaCl 0.9% with 2L 5% dextrose
  • if normal K+ on bloods need 40 mmol per day - give as 20 mmol into 2 bags
17
Q

what to check everytime you are prescribing fluids?

A
  • U&Es
  • fluid status
  • if giving for reduced urine output examine bladder for signs of retention
18
Q

what rate of maintenance fluids?

A
  • 24 hours divided by number of L to be give
    • 3L in 24 hours - 8hrly
    • 2L in 24 hours - 12 hrly
19
Q

what is standard VTE prophylaxis?

A

LMW heparin e.g. 5000 units dalteparin SC OD

compression stockings

20
Q

who shouldn’t get compression stockings?

A

peripheral arterial disease pt e.g. absent pulses distally

21
Q

what anti-emetic for nauseated patients?

A

regular

  • Cyclizine 50mg 8 hourly IM/IV/oral (SE fluid retention)
  • Metoclopramide 10mg 8 hourly IM/IV if HF
  • Ondansetron 4mg or 8mg 8 hourly IV/oral
22
Q

who should metoclopromide be used with caution/not used?

A
  • parkinson’s
  • young F - risk of dyskinesia
23
Q

what anti-emetic for patients who are not-nauseated at the current moment?

A

prescribe as needed (PRN)

  • Cyclizine 50mg 8 hourly IM/IV/oral (SE fluid retention)
  • Metoclopramide 10mg 8 hourly IM/IV if HF
24
Q

what pain releif for neuroleptic?

A

shooting, stabbing or burning

1st line

  • amitriptyline 10mg oral at night
  • pregabalin 75mg oral 12 hourly
25
Q

what analgesia for diabetic neuropathy?

A

duloxetine 60mg OD oral

26
Q

analgesia prescription for regular and PRN based on severity of pain

A
27
Q

what anti-emetic can be used in parkinson’s and why?

A

cyclizine - anti-histamine MOA

domperidone with anti-DA MOA (doesn’t cross BBB unlike metoclopramide)

28
Q

what are the signs of anti-muscarinic toxicity?

A
  • dilated pupils
  • loss of accommodation
  • dry mouth
  • tachycardia
29
Q

what do these signs suggest:

  • dilated pupils
  • loss of accommodation
  • dry mouth
  • tachycardia
A

anti-muscarinic toxicity

elderly are more vulnerable to it, often start on lower doses

e.g. oxybutinin