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Infection and Immunity > PREP > Flashcards

PREP Flashcards

1
Q

what are the red complex bacteria

A

p gingivalis
t forsythia
t denticola

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2
Q

what is the food source for p gingivalis

A

iron

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3
Q

what percent of patients have p gingivalis in their biofilm?

A

85%

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4
Q

what two characteristics do p gingivalis have

A

lipopolysaccharide
gram negative

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5
Q

what does lps release

A

endotoxins

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6
Q

what is a result of the release of endotoxins by lps

A

septic shock, skin lesions, high fever

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7
Q

what is PPAD

A

peptidylarginine deiminase

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8
Q

what is the bacteria that releases ppad

A

p gingivalis

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9
Q

when there is HIGH RANKL and LOW OPG;

A

increase in osteoclasts
(bone resorption)

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10
Q

when there is LOW RANKL and HIGH OPG

A

decrease in osteoclasts
(no bone resorption)

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11
Q

what kind of diseases are contagious

A

communicable diseases

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12
Q

when can communicable diseases be transferred

A

any phase

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13
Q

what are the 5 mechanisms of action

A

inhibit cell wall synthesis
inhibit protein synthesis
inhibit metabolic activity
inhibit nucleic acid synthesis
alter cell membrane

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14
Q

what is the mnemonic for the stages of viral replication

A

A PURple Apple Might Redden

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15
Q

list the stages of virus replication

A

attachment
penetration
uncoating
replication
assembly
maturation
release

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16
Q

(stage of virus replication)
binding to the host cell using specific receptor molecules in the plasma membrane

A

attachment

17
Q

(stage of virus replication)
requires energy by the host cell
endocyosis or phagocytosis

A

penetration

18
Q

(stage of virus replication)
breakdown of the capsid and release of genome into the cell to be replicated/transcribed

A

uncoating

19
Q

(stage of virus replication)
proteins that will be incorporated into the virion are made through expression of viral genes

genome is copied

A

replication

20
Q

(stage of virus replication)
newly created components collect at a site and form an immature virus particle

A

assembly

21
Q

(stage of virus replication)
changes that result in infectious virus particles
capsid changes are often involved

A

maturation

22
Q

(stage of virus replication)
release of virion into extracellular environment

A

release

23
Q

pro of broad spectrum antibiotic

A

not specific

24
Q

con of broad spectrum antibiotic

A

can hurt oral microflora

25
Q

pro of narrow spectrum antibiotics

A

very specific

26
Q

con of narrow spectrum antibiotic

A

won’t harm microflora

(if you dont know it, you cant attach it)

Infection and Immunity (4 decks)

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