Prep

Question 1

Who can you not offer tenofovir alone to?

Answer 1

MSM-lack evidence rather than lack effect.

Can use in Heterosexuals

Question 2

Who is there no evidence regarding effectiveness prep?

Answer 2

Trans men
Trans women men or women frontal sex

Question 3

What do BHIVA say re prep and feminising hormones?

Answer 3

Likely no interaction. Diff metabolism and clearance. Acknowledge concerns as may effect prep adherence

Ditto for masculinising

Question 4

What is minimum eGFR to start TDF FTC Prep?

Answer 4

> 60ml (normal is >90ml)

Question 5

Can you start Prep on basis of negative 3rd gen test?

Answer 5

Yes as long as no concern re seroconversion but must send 4th gen On starting.

Question 6

Who needs 6/12 renal monitoring in prep?

Answer 6

Age 40+
60-90 ml GFR
Or RF renal

Question 7

How does it work?

Answer 7

Prevents replication infected cells allowing clearance

Question 8

Which msm can’t have EBD?

Answer 8

Hep B