PRELIMS Flashcards
the mosy treatable cancer
breast cancer
this malignancy is most treatable when it is detected early
breast cancer
the most important innovation in breast cancer control since the radical mastectomy was introduced by ______ in 1898
Halstead
its primary goal is to detect breast cancer if it is palpable
mammography
in _____, a group of male radiologists in Rochester, NY assembled around a view box admiring the chest xray of a buxom woman
1924
father of mammography
Robert Egan, MD
He is a German physician
In 1913, he reported the radiographic appearance of breast cancers
Using radiographic studies of cancerous breasts removed at surgery, he described the mechanism of how breast cancer spread
Dr. Soloman
In 1927, he made the first published radiograph of a living person’s breast in a german medical textbook on malignant tumors
Otto Kleinschmidt
Year when publications on mammography appeared in South America, US and Europe but still the use of mammography for the diagnosis of breast cancer received little clinical interest
1930s
Year when mammography was considered a reliable clinical tool because of such refinements as low kilovoltage xray tubes with MOLYBDENUM targets and high detail industrial grade xray film
Mid 1950s
In 1960s, ________ was introduced and was popularized by WOLFE AND RUZICKA
Xerography
______ substantially lowered the radiation dose received by the px compared with the dose received using industrial grade xray film
Xerography
many physicians found the xerographic images easier to understand and evaluate, ____________ became widely used for evaluating breast diseases
xeromammography
______ company first introduced the combination of higher resolution, faster speed xray film and an intensifying screen
duPont company
year when breast cancer detection demonstration project was implemented
1973
in this project, 280k women underwent annual screening for breast cancer for 5 years at 29 locations throughout the US
organized by the AMERICAN CANCER SOCIETY and NATIONAL CANCER INSTITUTE
this project demonstrated unequivocally that screening, physical exam, mammography and BSE could provide an early diagnosis
breast cancer detection demonstration project
In 1975, _____ and duPont improved screen film combinations
by this time, extremelu high quality mammography images could be produced with very low patient radiation exposures
Kodak and duPont
In 1992, Mammography _______ ______ Act (MQSA) was implemented to mandate the maintenance of high quality breast cancer screening programs
Mammography Quality Standards Act
3 Risk Factors
Age
Hormonal History
Family History
the incidence of breasst cancer increases with ____
age
________ influence the glandular tissye of the breast during the development, pregnancy and lactation
however, hormone levels decline at the onset of ________
hormonal influence ; menopause
as a result, the glandular breast tissue is ____ sensitive to carcinogens during menarche
more sensitive
___ risk women inckude those with early menses, late menopause, first birth after age 30 years and nullipanity
high risk
a woman whose daughter, sister or mother previously developed breast cancer, especially at an early age, is at higher risk of developing the disease
studies have shown that only 13.6% of known breast cancers are found in women with a family history of the disease
family history
______ are lobulated glandular structure located within the superficial fascia of the anterolateral surface of the thorax of both males and females
breast
_______ glands divide the superficial fascia into anterior and posterior components
mammary glands
the breasts are rudimentary and without function
are only rarely subject to abnormalities such as neoplasms that require radiologic evaluation
male breasts
secondary sex characteristics and function as accessorry glands to the reproductive system
female breast
each breast is usually _____ shaped with the base or posterior surfacr of the breast overlying the PECTORALIS MAJOR and SERRATUS ANTERIOR MUSCLES
cone
these muscles extend from the second or ______ rib inferiorlu to the sixth or _____ rib and from near the lateral margin of the sternum laterally toward the anterior axillay plane
third rib ; seventh rib
an additional portion of breast tissue, the _________ prolongation or ______ tail, extends from the upper lateral base of the breasts into axillay fossa
axillary prolonation ; axillation tail
the breast are support by ______ ligaments, suspensory ligaments that extend from the posterior layers of the superficial fascia through the anterior fascia inyo the subcutaneois tissue and skin
cooper’s ligaments
the adult female breast consists of 15 to __ lobes which are distributed so that more lobes are superior and lateral than inferior and medial
15 to 20 lobes
each lobe is divided into many ______ which are the basic structual units of breast
it contains the glandular elements or _____
lobules ; acini
______ _______ adolescent breast contains primarily dense connective tissue and casts a relatively homogenous radiographic image with little tissue differentation
post puberal adolescent breast
during _______, significant hypertrophy of glands and ducts occurs within the breast
this change causes the breasts to become extremely dense and opaque
during pregnancy