Prelims Flashcards
T or F
mood can Influence a person’s behavior and perception of the world
TRUE
Pervasive and sustained
* Feeling tone that is expressed internally
Mood
Types of Mood Disorders
Major depressive disorder/unipolar depression
Bipolar disorder
Cyclothymia and dysthymia
Hypomania
both manic and depressive
episodes or patients with manic episodes alone
Bipolar disorder
episode of manic symptoms that
does not meet the criteria for manic episode
Hypomania
as disorders that
represent less severe forms of bipolar disorder
and major depression, respectively.
Cyclothymia and dysthymia
Major ___episode:
* occurs without a history of a manic, mixed, or hypomanic episode
* must last at least 2 weeks
Depression
Characteristics of?
-changes in appetite and weight
- changes in sleep and activity
- lack of energy
- feelings of guilt
- problems thinking and making decisions
- recurring thoughts of death or suicide.
Depression
is a distinct period of an abnormally and
persistently elevated, expansive, or irritable mood
lasting for at least 1 week (or less)
Mania
Characteristics of?
A hypomanic episode:
- lasts at least 4 days
- similar to a manic episode
- except that it is not sufficiently severe to cause impairment in social or occupational functioning
- no psychotic features are present.
T or F
Manic and hypomanic are both associated with:
* inflated self-esteem
* decreased need for sleep
* Distractibility
* great physical and mental activity
* overinvolvement in pleasurable behavior
TRUE
Bipolar I disorder, Mixed Episode, Bipolar II Disorder are types of what disorder?
Mania
a clinical course of one or more manic episodes and,
sometimes, major depressive episodes.
Bipolar I disorder
a period of at least 1 week – both a manic episode and a major depressive episode occur almost daily.
Mixed Episode
- A variant of bipolar disorder – episodes of major
depression and hypomania (rather than mania)
Bipolar II Disorder
at least 2 years of depressed mood
* not sufficiently severe to fit the diagnosis of major depressive episode.
Dysthymic disorder
- at least 2 years of frequently occurring
- hypomanic symptoms cannot fit the diagnosis of manic episode
- depressive symptoms that cannot fit the diagnosis of major depressive episode.
Cyclothymic disorder
T or F
* Women
* more likely than men to present a mixed picture
* higher rate of being rapid cyclers, defined as having four or more manic episodes in a 1-year period
TRUE
- Of the biogenic amines, ___-and ____are the two neurotransmitters most implicated in the pathophysiology of mood disorders.
norepinephrine and serotonin
Downregulation or decreased sensitivity of beta-adrenergic
receptors = clinical antidepressant responses
Norepinephrine
Depletion of serotonin = precipitate depression, ( suicidal impulses :
CSF - serotonin metabolites and less serotonin uptake sites on platelets)
Serotonin
▬ Reduced in depression and increased in mania.
Dopamine
Depressive disorders are associated with several immunological abnormalities, including decreased lymphocyte proliferation
- Immunological Disturbance
- CT and MRI Brain
- abnormal hyperintensities in subcortical regions
- periventricular regions
- basal ganglia
- thalamus.
- Most common in bipolar I disorder
Structural and Functional Brain Imaging
four brain regions in the regulation of normal emotions:
prefrontal cortex (PFC)
anterior cingulate:
hippocampus
amygdala
learning and memory
hippocampus
: station for processing novel stimuli
amygdala
ntegration of attentional and emotional inputs =
facilitates control of emotional arousal, particularly when goal attainment
has been thwarted or when novel problems have been encountered
anterior cingulate
representations of goals and appropriate responses to obtain these goals = multiple, conflicting behavioral responses
prefrontal cortex (PFC)
= long-lasting changes in the brain’s biology
= alter the functional states of various neurotransmitter and intraneuronal signaling systems
loss of neurons
and an excessive reduction in synaptic contacts.
Life Events and Environmental Stress
high risk of undergoing subsequent episodes even without an external stressor.
losing a parent before age 11 – Unemployment
* loss of a spouse
Ewan take note
Persons with certain personality disorders may be at greater risk for depression
What are these disorders?
OCD
* Histrionic
* Borderline
antisocial or paranoid personality disorder can use projection and
other externalizing defense mechanisms to protect themselves from
their inner rage.
Personality Factors
T or F
depression can be linked to real or imagined object loss
TRUE
T or F
* Happiness may occur as a single episode or may be recurrent.
* There’s a certain cause that triggers
FALSE
* Depression may occur as a single episode or may be recurrent.
* There’s a certain cause that triggers
- Depression may occur as a single episode or may be recurrent.
- There’s a certain cause that triggers
- Major Depressive Disorder, Single Episode
- Patients who are experiencing at least a second episode of
depression - DSM-5 requires that distinct episodes of depression be separated
by at least 2 months during which a patient has no significant
symptoms of depression.
Major Depressive Disorder, Recurrent
- The DSM-5 criteria for a bipolar I disorder requires the presence of a distinct period of abnormal mood lasting at
least 1 week
Bipolar I Disorder
characterized by depressive episodes and hypomanic episodes during the course of the disorder
Bipolar II Disorder
According to DSM-5, patients must be experiencing their first manic episode to meet the diagnostic criteria for bipolar I disorder, single manic
episode.
Bipolar I Disorder, Single Manic Episode
Manic episodes are considered distinct when they are
separated by at least 2 months without significant
symptoms of mania or hypomania.
Bipolar I Disorder, Recurrent
The two basic symptom patterns in mood disorders are
Depression and mania.
T or F
Bipolar I Disorder vs Major Depressive Disorder
* Can’t be differentiated by patient’s history, family history, and future course
FALSE
Bipolar I Disorder vs Major Depressive Disorder
* Can be differentiated by patient’s history, family history, and future
course
Clinical features of depression among Children
- School phobia
- excessive clinging to parents
Clinical features of depression among Adolescents
- Poor academic performance
- substance abuse
- antisocial behavior
- sexual promiscuity, truancy, and running away
Clinical features of depression among Older People
may be correlated with low socioeconomic status, the loss of a
spouse, a concurrent physical illness, and social isolation.
Response to questions with single words and exhibit delayed responses to questions.
Speech
During a speech examination, The examiner may literally have to wait ___ minutes
for a response to a question.
2-3 minutes
Depressed patients with delusions or hallucinations are said to have a major depressive episode with psychotic features. Even in the absence of delusions or hallucinations, some clinicians use the term psychotic depression for grossly regressed depressed patientsmute, not bathing, soiling
Perceptual Disturbances
Depressed patients customarily have negative views of the world and of themselves including nondelusional ruminations about loss, guilt, suicide, and death.
Thought