Preinvasive Lesions

Question 1

Preinvasive Lesions

Answer 1

1. Squamous dysplasia and carcinoma in situ
2. Atypical adenomatous hyperplasia (AAH)
3. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

Question 2

Squamous dysplasia and carcinoma in situ

Answer 2

cigarette smoking

tracheobronchial pseudostratified epithelium to metastatic squamous mucosa

Question 3

Dysplastic changes in Squamous dysplasia and carcinoma in situ

Answer 3

altered cellular polarity

increase cell sze

number of cell layers

N:C ratio

Question 4

Gradations Squamous dysplasia and carcinoma in situ

Answer 4

mild
moderate
severe

Question 5

Atypical Adenomatous Hyperplasia

Answer 5

smaller than 5.0 mm

epithelial cell s lining the alveoli similar to type II pneumocytes

similar to adenocarcinoma in situ

Question 6

Diagnostics AAH

Answer 6

thin CT scan

Question 7

Lesions AAH

Answer 7

typically small (5 mm)

ground glass appearance

Question 8

Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia

Answer 8

rare

diffuse proliferation of neuroendocrine cells

without invasion

Question 9

Lesions of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia

Answer 9

small, less than 5 mm

Question 10

if lesion of DIPNCH over than 5 mm

Answer 10

Carcinoid tumors