Pregnancy Test Flashcards
Study of ovulatory & menstrual cycle
Female fertility
hyperplasia of uterus/endometrium
Follicular proliferation phase
oocyte is already matured
• Increased body temperature
• Increased cervical mucus
• Weight gain
• Pelvic pain
• Irritability
Ovulatory phase
ovary luteolysis
Luteal/Secretory phase
regular, periodic, physiologic extrusion of blood, mucus & cellular debris from the uterus
Mestruation
- 1st menstruation
Menarche
- cessation of menstruation
Menopause
Ovum must be fertilized within
1-2 days
If the ovum is not fertilized
Luteolysis
where fertilization takes place
• Within 6-8 days
Ampulla of fallopian tube
Ampulla of fallopian tube: where fertilization takes place
• Within
6-8days
will migrate to the upper portion of the uterus
Zygotes
HCG works when progesterone is _________(increase/decreased)
Decrease
must be fertilized within 1-2 days in
Ovum
Increased in Follicular phase
Estrogen
Increased after ovulation
Follicle stimulating hormone & Luteinizing hormone
Increased in luteal phase
Progesterone
Decreased progesterone = _________ HCG
Increased
Detectable 10-14 days after conception
HUMAN CHORIONIC GONADOTROPIN (HCG)
Secreted by syncytiotrophoblast
Human chronic gonadotropin
Properties of HCG
Polypeptide chain
Alpha subunit (14,000 dalton)
Beta subunit (22,000 dalton)
IMPORTANCE OF PREGNANCY TESTS
• Confirmnormalpregnancy.
• Evaluateabnormalpregnancy.
•Determineiftherehasbeencompleteorincomplete abortion.
• DifferentiateGestationalTrophoblasticdisease
(myoma/H-mole) & other pelvic disease.
Peak level of HCG
60-90 days
RBC covered/coated with HCG incubated with anti-HCG serum + urine
Hemagglutination inhibition
