pregnancy physiology part 1 Flashcards

1
Q

when must fertilisation occur after ovulation?

A

24 hrs

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2
Q

where does fertilisation occur?

A

Fallopian tube

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3
Q

how is a blastocyst formed?

A

through division of zygote

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4
Q

where does a blastocyst implant?

A

in the wall of the uterus-endometrium

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5
Q

what are the two layers of the uterus?

A

outer muscular layer- myometrium

inner layer- endometrium

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6
Q

what cells form the placenta during implantation?

A

trophoblasts

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7
Q

what finger-like projects are found in the placenta?

A

placental villi-chorionic tissue

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8
Q

what are the placenta villi surrounded by?

A

maternal blood

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9
Q

how are metal blood and maternal blood seperated?

A

by capillary wall

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10
Q

where does the maternal blood enter to exchange with fetal blood?

A

intervillus spaces of placenta villi

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11
Q

do maternal and fetal blood mix?

A

no

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12
Q

what systems does the placenta function as? and is this controlled by the foetus itself or the mother?

A

digestive, respiratory and kidneys and controlled by the mother

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13
Q

what sort of placental diffusion occurs for things like water, electrolytes, 02 etc?

A

simple

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14
Q

what sort of molecules require active transport?

A

glucose and amino acids

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15
Q

how is cholesterol transported across placenta?

A

receptor-mediated endocytosis

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16
Q

what may cause harm to the foetus if crossed via placenta?

A

drugs
alcohol
thalidamide
smoking
aids

17
Q

what else does the placenta act as?

A

endocrine gland

18
Q

what is the purpose of placental hormones?

A

to maintain the pregnancy

19
Q

what placental hormones are produced?

A

-hCG
-estrogen
-progesterone

20
Q

what hormone is detected by pregnancy tests?

A

hCG

21
Q

when does hCG rise in pregnancy?

A

early pregnancy then drops

22
Q

what is the purpose of the rise in hGC in early pregnancy?

A

prolongs the life span of corpus luteum

23
Q

what is the purpose of corpus luteum?

A

produces oestrogen and progesterone

24
Q

what stimulates testosterone release in males?

A

hCG

25
Q

how many weeks in hCG and corpus luteum needed?

A

around 10 weeks then the placenta can form oestrogen and progesterone on its own

26
Q

why is the placenta unable to produce oestrogen in early pregnancy?

A

it does not have the specific enzymes needed

27
Q

why is the placenta unable to produce progesterone in early pregnancy?

A

the placenta is too small to make enough

28
Q

how is oestrogen formed in the placenta?

A

cholesterol makes DHEA which forms oestrogen by adrenal cortex

29
Q

how is progesterone formed in the placenta?

A

from cholesterol

30
Q

what is the purpose of E and P in maintaining the pregnancy?

A

it allows the maintenance of thick endometrial tissue and stops menstruation

31
Q

what are the two purposes of estrogen?

A

-growth of myometrium
-growth of mammary milk ducts (milk ejects)

32
Q

what are the 3 purposes of progesterone?

A

-prevent miscarriage by preventing myometrium contractions
-stop vaginal contamination
-stimulates milk glands in breasts