Pregnancy Complications Flashcards
Preeclampsia
Inadequate albumin (protein) in the blood causes fluid to leak from blood cells, resulting in reduced blood volume, hemocoricontraction, and sometimes generalized edema
How does preeclampsia effect the kidneys?
It reduces blood flow to kidneys which triggers rise in Bp
-blood flow to uterus is reduced, leads to fetal growth restriction
-severe hypertension leads to microthrombi (tiny clots) to form
-microthrombi stretch the filtering slits in kidneys so late protein molecules skip through, leading to protein uria
Early signs of preeclampsia
High hematocrit
Hypertension
Protein in urine
Lab work that shows elevated liver enzymes
BUN
Uric acid
Sever preeclampsia
Microthrombi
Microthrombi can do significant harm to other parts of the body
Impairs circulation to liver (causes epigastric pain)
Severe preeclampsia and liver involvement may develop HELLP syndrome
Hemolysis, elevated liver enzymes, low platelet counts
Turner syndrome
Symptoms?
Treatment?
Chromosomal disorder in which a female is born with only one X chromosome
Symptoms:
Short stature
Delayed puberty
Infertility
Heart defects
Treatment: hormone therapy
Tay-sachs disease
Rare inherited disorder that destroys nerve cells in the brain and spinal cord
Tay-sachs disease is typically found in people with certain ancestry as Eastern European Jews
Tay-sachs disease symptoms
Slow development appears around 6 months
Symptoms progress until they lead to death often around age 4
No cure
Which drug can be used to treat early diagnosis of ectopic pregnancy?
Methotrexate
How does methotrexate work?
Inhibits folic acid metabolism thus inhibiting DNA synthesis and cell division so embryo does not develop further and is reabsorbed
Methotrexate
Drug used to treat early diagnosis of ectopic pregnancy.
Teratogen
Any substance that can harm the fetus or cause fetal anomalies is called a teratogen
Question
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During pelvimetry, a primigravida is found to have a diagonal conjugate of 10 cm. Based on this information, the midwife would expect her labor to be:
prolonged, with failure of the head to engage