Pregnancy and Prenatal Care Flashcards
Chadwick sign
Bluish discoloration of the vagina and cervix
Goodell sign
Softening and cyanosis of the cervix at or after 4 weeks
Ladin sign
Softening of the uterus after 6 weeks
Cardiovascular changes in pregnancy
- Increased cardiac output (30-50%)
- (+)SV, followed by (+)HR
- (-)SVR due to elevated progesterone
Pulmonary changes in pregnancy
(+)Tidal volume
(-)Expiratory reserve volume
What facilitates oxygenation and ventilation of the fetus?
(-)PaCO2 (arterial), creating CO2 gradient b/w mother and fetus
Hyperemesis gravidarium (define, 2 features)
- Severe morning sickness
- Weight loss (> 5% pre-pregnancy weight)
- Ketosis
GI changes in pregnancy (3)
- Prolonged gastric emptying (reflux)
- Decreased GE sphincter tone (ptyalism)
- Decreased large bowel motility
Renal changes in pregnancy (3)
- Increased GFR (50%)
- Decreased BUN and creatinine (25%)
- Increased RAAS activation, but normal serum Na
Hematologic changes in pregnancy (3)
- Dilutional anemia
- Elevated levels of fibrinogen, factors VII-X
- Normal clotting and bleeding times
What produces increased estrogen in pregnancy, and from what is it derived?
- Produced primarily by the placenta
- Derived from circulating precursors in plasma from maternal adrenal glands
Effects of Human Placental Lactogen (hPL) (2)
- Lipolysis (increased circulating free FAs)
- Insulin antagonist (diabetogenic, +protein synthesis)
Urine tests in pregnancy (3)
- Glucose
- Protein (preeclamsia)
- Leukocyte esterase
Elevated/decreased maternal serum AFP is associated with:
- Elevated: neural tube defects
- Decreased: aneuploidies (Down syndrome)
Components of the quad screen:
- Estriol
- AFP
- Inhibin A or B
- B-hCG
Treatment offered to patients who are Rh negative
Rho-GAM (good for 12 weeks)
Third-trimester labs (3-5):
- Hematocrit (near nadir)
- RPR/VDRL
- Glucose loading test
- High risk: GC/CT
- Group B strep
Components of the biophysical profile (5):
- Amniotic fluid volume
- Fetal tone
- Fetal activity
- Fetal breathing movement
- Nonstress test (NST)