Infectious Diseases in Pregnancy Flashcards

1
Q

Most common causes of ASB and UTIs:

A
  • E. Coli (70%)
  • GN enterobacteria (Kleb, Proteus)
  • Staph epi (coagulase-negative)
  • GBS, Entero
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2
Q

Initial treatment of asymptomatic bacteriuria (ASB):

A

3-7 days

  • Amoxicillin
  • Nitrofurantoin
  • Bactrim
  • Keflex
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3
Q

Pregnant patients presenting with hypoxemia, dyspnea, and pulmonary edema most likely have:

A

ARDS

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4
Q

Treatment of pyelonephritis during pregnancy:

A
  • Hospital admission
  • Fluid resuscitation
  • IV antibiotics (cephalospirins, amp/gent)
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5
Q

Management for patients with pyelo not responding to antibiotics:

A

Renal ultrasound for perinephric or renal abscess

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6
Q

Management of pregnant women with 1 episode of pyelo and 2+ ASB/cystitis:

A

Antimicrobial ppx (Nitrofurantoin or Bactrim) for the remainder of pregnancy

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7
Q

Criteria for diagnosing bacterial vaginosis (Amsel’s criteria, 4):

A

(1) Thin/white/gray homogeneous discharge
(2) Fishy odor
(3) pH > 4.5
(4) > 20% clue cells

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8
Q

Common organisms in BV (3):

A
  • Gardnerella vaginosis
  • Bacteroides
  • Mycoplasma hominis
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9
Q

Treatment of BV in pregnancy:

A

1 week:

  • Oral metronidazole
  • Oral Clindamycin
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10
Q

Diagnosis of chorioamnionitis:

A
  • Maternal fever
  • Elevated maternal WBC
  • Uterine tenderness
  • Materna/fetal tachycardia
  • Foul-smelling amniotic fluid
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11
Q

Management of outbreak of herpes in pregnant woman:

A

Oral acyclocir/valacyclovir, 10 days

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12
Q

Guidelines for VZV vaccination:

A
  • Live virus; highly immunogenic
  • Can immunize prior to conception
  • Contraindicated in pregnancy
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13
Q

Congenital varicella syndrome (4):

A
  • Skin scarring
  • Limb hypoplasia
  • Chorioretinitis
  • Microcephaly
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14
Q

Parvo B19 infection in pregnancy:

A
  • Crosses placenta to infect bone marrow
  • Suppression of erythropoiesis
  • CHF
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15
Q

Sonographic findings of CMV infection:

A
  • Microcephaly
  • Ventriculomegaly
  • Fetal hydrops
  • Growth restriction
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16
Q

Leading cause of congenital hearing loss

A

CMV

17
Q

Congenital rubella syndrome (4):

A
  • Hearing loss
  • Eye defects
  • CNS defects
  • Cardiac malformations
18
Q

Cardiac malformations in congenital rubella:

A
  • PDA (more common)

- Supravalvular pulmonic stenosis (more specific)

19
Q

Treatment for gonorrhea:

A

IM ceftriaxone

20
Q

Treatment for chlamydia:

A
  • Azithromycin
  • Amoxicillin
  • Erythromycin
21
Q

Treatment for syphilis:

A

Penicillin

22
Q

Treatment of toxoplasmosis:

A

Pyrimethamine, sulfadiazine

23
Q

Risks of ciprofloxacin in pregnancy:

A
  • Renal anomalies

- Additional?

24
Q

Most common cause(s) of chorioamnionitis:

A
  • Polymicrobial (from rectum)
  • Mycoplasma, Ureaplasma
  • Garnerella, E. coli, entero, GBS
25
Q

Treatment of HIV in pregnancy:

A
  • HAART in the second trimester
  • C-section if VL > 1000
  • Avoid breastfeeding