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ELC Pharmacology > Pregnancy and labour > Flashcards

Pregnancy and labour Flashcards

1
Q

What is given to mothers in preterm labour for lung maturation?

A

Glucocorticoids:
Betamethasone
Dexamethasone IM

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2
Q

What is given to preterm babies?

A 
Surfactant:
Beractant (calf)
Survanta (calf)
Poractant (pig)
Curosurf (pig)
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3
Q

What is poractant?

A

Pig surfactant, given to preterm babies

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4
Q

What are survanta and beractant?

A

Calf surfactant, given to preterm babies

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5
Q

Name 2 pig surfactants

A

Poractant

Curosurf

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6
Q

Name 2 calf surfactants

A

Beractant

Survanta

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7
Q

Name the 5 classes of tocolytic

A 
NSAID
Oxytocin receptor antagonist
Ca2+ channel blocker
B2 agonist
MgSO4
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8
Q

What is a tocolytic?

A

Delays childbirth by inhibiting contractions

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9
Q

Name the B2 agonists used as tolytics

A

Ritodrine

Terbutaline

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10
Q

What is rotodrine?

A

A B2 agonist, used as a tocolytic in preterm labour

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11
Q

Name the Ca2+ channel blocker used as a tocolytic

A

Nifedipine

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12
Q

Name an oxytocin receptor antagonist

A

Atosiban

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13
Q

What is atosiban used for?

A

As a tocolytic in preterm labour

Oxytocin receptor antagonist

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14
Q

What NSAID is used as a tocolytic?

A

Indomethacin

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15
Q

Why is indomethacin used in preterm labour

A

NSAID so decreases formation of prostaglandins so less uterine contractions

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16
Q

What drugs are given in labour to help with contractions and prevent post partum haemorrhages?

A

Oxytocin (IV in labour)

Oxytocin and ergotamine IM to prevent haemorrhage

17
Q

What drug is a PGE2?

A

Dinoprostone

18
Q

What is dinoprostone?

A

A PGE2 drug used in labour to enhance contractions, dilation and cervical ripening

19
Q

What drugs should be avoided in pregnancy? Name 8

A

Lithium, cytotoxics, anticonvulsants, iodine, sex hormones, aminoglycoside antibiotics, tertracycline, ACE inhibitors

20
Q

Role of hCG?

A

Released by embryo after 5-6 days, rescues corpus luteum and gives +ve pregnancy test

21
Q

What two drugs are used for abortion?

A

Prostaglandins (gemeprost)

Progesterone receptor antagonists (mifepristone)

ELC Pharmacology (6 decks)

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