Pregnancy A&P ppt Flashcards
Josh's guide to the A&P of OB
Parturients are rarely in _________ condition
optimal
Parturients are always considered what?
A “full stomach”
average weight gain of the Parturient
17%
2 basic reasons you have cardiovascular changes in pregnancy
the developing fetus
labor and delivery events with mom
CV physiological changes
IVF
volume/constituents
CO
IVF- increased
volume/constituents- diluted
CO- increased
CV system
Increased IVF volume and constituents begins when?
at full term can be how much? (mLs)
1st trimester
1500mL
CV system
plasma volume increases what %
erythrocyte volume increases what %
what happenes to albumin (plasma protein)
plasma volume- 45% (40-50%)
erythrocyte volume- 20%
albumin (plasma protein)- decreases
CV system
do to the extra IVF what will develope?
dilutional anemia
CV system
EBL- vaginal? c-section?
300-500 mL
800-1000mL
CV system CO increases by what % in the following: 10th week of gestation? 3rd trimester post delivery
10th week- 10%
3rd trimester- 40-50%
post delivery- 60-80% (up to 180%)
CV system
Stroke volume increases what %?
30%
thus leading to increased CO
CV system
Heart rate increases what %?
15-25%
thus eading to increased CO
CV system
what happens to SVR??? and to what %
decreases 20%
CV system
what happens to SBP since SVR decreases?
nothing stays about the same
CV system
what happens to DPB since SVR decreases?
decreases 15%
CV system
PVR decreases by how much
35%
CV system
what happens to CVP?
No changes
CV system
when does Supine Hypotension Syndrome (SHS) occur
near term
CV system
s/s of SHS
diaphoresis
N/V
changes in cerebration
CV system
what is SHS
compression of the IVC by the gravid uterus, while in supine position
CV system
how does SHS work?
decreased venous return
leads to decreased CO
leads to decline in systemic BP
CV system
what happens with aortocaval compression
decreased SBP
decreased in uterine and placental blood flow
CV system
when a prego gets nauseated what do you do?
give ephedrine
CV system
what can help with SHS or aortocaval compression
LUD or RUD
CV system
what is the BEST treatment for SHS or Aortocaval compression
LUD with 15 degree right hip elevation
CV system
what is the prefered treatment for SHS or aortocaval compression
prevention
CV system
normal fetal HR
Fatal tachycardia?
Fetal bradycardia
Normal- 110-160
tachy- >160
brady-< 100
CV system
patho of SHS (of mechanism in how it actually causes hypotension)
a compensitory response
- paravertebral venous plexuses => azygos vein=> SVC
- reflex increases peripheral SNS => increases SVR, maintains SBP despite decreased CO
Uncompensated
- Decreased SBP < 100mmHg
=> fetal acidosis
=> bradycardia
CV system
what is the normal compensitory response to SHS?
increased SVR
CV system
what is the sympathetic response to regional anesthesia?
vasodilation
Hypotension
decreased uterine and placental blood flow (fetal acidosis)
CV system
pregnant women are much more dependent on the ____ - _____ _____ for maintenance of BP (supports MAP)
renin-angiotensin system
CV system
by the 3rd trimester serum renin levels are __x’s the non-pregnant level
3x’s
Pulmonary system Upper airway
what happens to the cappillary membranes
engorgment
Pulmonary system Upper airway
what happens to the vocal cords and arytenoids
edematous
Pulmonary system Minute Ventilation
MV is increased what % during 1st trimester?
what % TV and RR
50%
TV 40%
RR 10%
Pulmonary system Minute Ventilation
What is the stimulus for increased MV?
what else does it do?
Progesterone
sedation
Pulmonary system Minute Ventilation
the 50% increase in MV will cause what problem?
what is the decrease from what to what?
any changes in pH?
decreased PaCO2
from 40 mmHg to 30 mmHg
No changes in pH
Pulmonary system Lung Volumes
what happens to the diaphragm by the 3rd trimester
moves cephalad
Pulmonary system Lung Volumes
sense the diaphragm moves cephalad the FRC decreases by ___% by term.
20%
Pulmonary system Lung Volumes
The decreased FRC causes greater ______ ______ which ultimatly leads to _______
closing capacity
atelectasis
Pulmonary system Lung Volumes
what are the anesthestic considerations in relation to MV increase?
increased MV and decreased FRC => increased alveolar concentrations of inhaled anesthestics.
basically gas uptake is faster!!!
Pulmonary system Arterial Oxygenation
what happens in early pregnancy to PaO2?
what happens later in pregnancy to PaO2?
early- above 100 mmHg
later- normal or slghtly decreases (airway closure)
Pulmonary system Arterial Oxygenation
there is marked decrease in PaO2 with apnea. mainly due to what 3 things
decreased FRC
Decreased CO r/t aortocaval compression
Increased oxygen consumption
Pulmonary system Physiologic changes
what to want to do with the OETT
select a smaller cuffed ETT (6.0-7.0)
Pulmonary system Physiologic changes
what airway do u always want to avoid? and why?
nasal airways
vascular congestion
Pulmonary system Physiologic changes
what are some reasons that make these individuals difficult airways?
short neck
weight gain
large breast
Pulmonary system Physiologic changes
as stated before decreased FRC and increased MV will cause what?
rapid alveolar consentration of IA
Pulmonary system Physiologic changes
rapid _________ with apnea
desaturation
Pulmonary system Physiologic changes
always _________ for 5 minutes with GA, and ______ during regional anesthesia
preoxygenate
oxygenate
Nervous System CNS
why are is there a decreased anesthetic requirement?
MAC lower VA
progesterone produced sedation
Increased inhation agent r/t pulm changes
what is ALWAYS contraindicated in a prego?
LMA
Nervous System CNS
CNS depression leads to what and why during intubation?
increased risk for aspiration
due to impaired upper airway reflexes
Nervous System CNS
due to the increased risk for aspiration due to impaired upper airway reflexes what typed of intubation tech should be used
RSI
Cricoid pressure
prohesterone may produce what?
sedation
Nervous System Physiological changes
what 3 things change in the nervous system (mainly in r/t the spinal cord)
engorgement of epidural veins
decreased epidural space
decreased volume in CSF
Nervous System Physiological changes
due to the engorgement of epidural veins, the decreased epidural space, and decreased volume of CSF what are 2 important anesthestic considerations?
- exaggerated spread of LA
- Decreased in dose requirement by 30-50%
Renal system
the renal system changes usually start to occur when?
3rd month of pregnancy
Renal system
there is a ____ to _____% increase in RBF and GFR
50-60
Renal system
there is a 50% decrease in the upper normal limits of what labs? and what are their values
BUN-8 mg/dL
Creatinine-0.5 mg/dL
uterine blood flow is up to how much mL/min
500-700 mL/min
Is the uterus autoregulated
no, it depends on the mothers BP
the placental circulation is ______ proportional to the mean perfusion pressure across the uterus and ______ proportional to uterine vascular resistance
directly
inversely
what causes decreases in uterine blood flow?
mothers hypotension
do epidurals or spinal anesthesia alter uterine blood flow?
not if maternal hypotension is avoided
what do contractions do to uterine blood flow?
decreases it
what increases uterine vascular resistance in response to maternal stress and pain?
endogenous release of catecholamines
An Anesthetic consideration is that which pressor is NOT associated with significant decreases in uterine blood flow?
ephedrine
Placental exchange occurs primarily by what?
diffusion
palcental diffusion depends on what 5 things
maternal to fetal concentration gradients maternal protein binding molecular weight lipid solubility degree of ionization
fetal circulation
1) well oxygenated blood enters fetus from the placenta via the UMBILICAL VEIN
2) IVF has 3 sources
3) blood enters the RA from the IVC; better saturated blood enters LA via the FORAMEN OVALE
4) blood enter the LV and is ejected into the ASCENDING AORTA
5) returns to the heart via the SUPERIOR VENA CAVA and combines with the blood in the RA
6) enters RV and is ejected into the PULMONARY ARTERY, small amounts goes to the LUNGS the remainde shunted across the ductus arteriousus.
ductus venosus
shunts blood from the umbilical vein to inferior vena cava (bypassing liver)
Foramen Ovale
Shunts blood from the RA to LA
ductus arteriousus
shunts blood from pulmonary artery to descending aorta. (bypassing lungs)
the brain and upper body receive what type of blood?
well oxygenated
the abdomen and lower body receive what type os blood?
less well oxygenated blood
Stages of labor
1st- onset of regular contractions(latent and active stages) ends with full cervical dilation (10 cm at term)
2nd stage- begins with full dilation of the cervix, ends with delivery of baby
3rd stage- delivery of infant untill placenta is expelled
************** 1st stage Pain what type of pain? what causes the pain? what type of nerve fibers? where to the fibers origionate? pain characteristics?
-VISCERAL
-caused by uterine contractions an ddilation of cervix
-Autonomic C fibers
-enter the dorsal horn of the spinal cord T10-L1
-dull- aching pain
(how to remember For Jake)
know the C
visCeral pain
caused by Contractions and dilation Cervix
autonomic C fibers
2nd stage Pain what type of pain? what causes the pain? what type of nerve fibers? name of the nerves? where to the fibers origionate?
- SOMATIC
- caused by the stretching of the vagina and perineum by desecent of the fetus
- A-Delta
- pudendal nerves
- enter spinal cord at posterior roots S2-4
(how to remember Somatic Seecond stage remember the S)
Hepatic system
why may succinylcholine last longer in the prego r/t hepatic
25% in plasma cholinesterases activity
Hepatic system
why is the prego at increased risk for DVTs
hypercoaguble
Hepatic system
which coag factors are increased
all
Hepatic system
what happens to LDH, AST/SGOT, ALT/SGPT
increase
Hepatic system
what are anesthetic considerations r/t the Hepatic system
succinycholine and mivacurium may have prolonged effect due to increased liver enzymes
GI system
what aides in the retarding gastric emptying
the upward and backward displacement of the pylorus
GI system
the decreased gastric motility is r/t _________ thus causing increased gastric fluid volume
Progesterone
GI system
_________ stimulates gastric H+ ion secretion resulting in a lower pH of gastric fluid
Gastrin
GI system
what is the name for the aspiration Pneumonitis that occurs with volumes >25 mL and a pH < 2.5
mendelson’s syndrome
GI system
anesthetic considerations
all pregos are considered what?
full stomachs
what is the treatment for aspiration prophylaxis for all pregnant women? give doses and route!
Reglan 10mg IV
Zantac 50mg IV
Bicitra 30 mL PO
what is the main thing you must avoid with regional anesthesia (MOST IMPORTANT)
HYPOTENSION
which anesthetic techniques decreases the likelihood of fetal drug depression and maternal pulmonary aspiration?
Regional
does regional anesthesia influance the progress of labor or the ability to bear doen during the second stage of labor?
nope it shouldn’t
90% of deliveries are ________ presentation in either occiput transverse or occiput anterior position
cephalic
normal or abnormal?????
what are 2 abnormal presentations?
persistant occiput posterior
breech presentation
you should consider _______ and ______ presentation with multiple gestations and ussually consider a ______ _______
prematurity
breech
cesarean section
what is Beat to beat variability?
Is it normal?
what does it indicate?
FHR that varies 5-20 BPM
yes (completly normal)
nothing no worries
what is early decelerations?
is it normal?
what does it indicate?
- the slowing of the FHF that begins with the onset of uterine contraction
- yep (no worries no problems)
- nothing NOT indicative of fetal distress
****************** what is a late deceleration is it normal? what does it indicate? what test is recomended?
- slowing of FHF that begins 10-30 seconds after the onset of uteine contractions.
- nope never
- fetal distress
- fetal scalp pH
*************************** what are variable decelerations? they are generally characterized by what? thought to be caused by what? are the bad? how can you fix it?
- variable in magnitude, duration and time of onset
- generally characterized by a steep descent of FHR
- umbilical cord compression
- unless prolonged, they are usually benign
- changing maternal position
after birth of baby what is the first thing you suction and why
the babies nose- b/c it causes the first breath
in the newborn how do you evaluate and treat hypolovolmia
via the umbilical vein
for vascular resuscitation an ______ ______ ______ may be inserted. can be used for ABGs
umbilical arterial catheter