Pregnancy Flashcards
Termination of Preganancy (TOP) legal framework
1967 Abortion Act
TOP gestational restrictions
< 24weeks
When can TOP be carried out >24weeks
- Continuing the pregnancy is likely to risk the life of the woman
- Terminating the pregnancy will prevent “grave permanent injury” to the physical or mental health of the woman
- There is “substantial risk” that the child would suffer physical or mental abnormalities making it seriously handicapped
Legal requirements for an abortion
- 2 registered medical practitioners must sign to agree abortion is indicated
- It must be carried out by a registered medical practitioner in an NHS hospital or approved premise
Medical Abortion Tx
- Mifepristone
- Misoprostol 48hours later
Anti-D prophylaxis indication in Abortions
- Medical TOP: Rh-ve/ >10 wks gestation
- Surgical TOP: Rh-ve
TOP Surgical Tx
- Cervical dilatation and suction of the contents of the uterus (up to 14wks)
- Cervical dilatation and evacuation using forceps (14 - 24 wks)
Post TOP pregnancy test
Urine preg test 3wks post TOP
Abortion pill at home criteria
No more than 10wks gestation
Abortion pill at clinic criteria
10 - 24 wks gestation
TOP complications
- infection of the womb (uterus) ( PID)
- some of the pregnancy remaining in the womb
- excessive bleeding
- damage to the womb or entrance of the womb (cervix) Cervical incompetence
- Failure of the abortion (pregnancy continues)
Pre TOP Ix
- Preg testing to confirm pregnancy
- Assess Rhesus status
- May require blood group, FBC, haemaglobinopathies
- VTE assessment: coagulation screen
- STI screening and give prophylaxis treatment against chlamydia and anaerobes
Define TOP / Abortion
A procedure to end a pregnancy
Antenatal care initiation
through GP / self-referral to hospital of choice
When should the booking clinic occur?
1st mid-wife appt
Prior to 10wks of gestation
Drugs to avoid during preg
- Teratogenic: Roaccutane, methotrexate
- Chemotherapeutics: teratogenic in the 1st trimester
- Statins: can cause oligohydramnios
- Valporate: neurodevelopmental delay
1st Antenatal scan
Optional
Dating Scan
When is the dating scan performed during preg?
11-13wks + 6D
Dating Scan purpose
- Establish viability
- Date the pregnancy
- ?multiple pregnancy
- Measuring nuchal translucency
Combined screening
occurs at dating scan
- USS: Nuchal translucency
- Blood tests
4 factors
Aneuploidy Screening factors
- NT measurement w/gestational age
- Maternal age
- serum Beta hCG high
- PAP A (Pregnancy associated plasma protein A) low
Aneuploidy Screening high risk features
- Thick NT measurement
- Increase maternal age
- High beta-hCG
- Low PAP A
When is the most accurate time/sreening to screen for Down’s during pregnancy?
- 1st trimester
- Combined screening
Sensitivity of the combined screening for Down’s in the 1st trimester
- > 90% of T21 fetuses