Adenomyosis Flashcards
Define Adenomyosis
Adenomyosis is the presence of functional endometrial tissue within the myometrium of the uterus.
Adenomyosis Sx
- Menorrhagia (heavy period)
- Dymenorrhoea (Painful period)
- Dyspareunia (Pain during sex)
1st line imaging for suspected adenomyosis
TVUS
Definitive diagnosis of adenomyosis
histology - post hysterectomy
Adenomyosis Risk factors
- Multi-parity
- Previous uterine surgery
- 30-50 years old
Adenomyosis examination findings
Enlarged and Tender uterus on bimanual examination
Definitive treatment for adenomyosis
Hysterectomy
Adenomyosis 1st line Mx
for non-conceiving
Mirena coil
Adenomyosis non-hormonal Mx - for conceiving patients
Tranexamic acid
Mefenamic acid
when to use tranexamic acid
adenomyosis w/ Menorrhagia
Tranexamic acid drug class and MoA
Anti-fibrinolytic - reduces bleeding
Mefenamic acid drug class and MoA
NSAID - reduces bleeding and pain
when to use mefenamic acid
adenomyosis w/ dysmenorrhoea
what is the purpose of hormonal therapy in adenomyosis
To reduce the proliferation of the ectopic endometrial cells
adenomyosis alternative Tx
Uterine Artery Embolisation (UAE)