preggers Flashcards
EDD
expected date of delivery
LMP + 7 days, go back 3 mo add 1 yr
endometrium before and after preggers
before: basal arteries and spiral art shed with each LH change
after: spiral arteries confluent and drop womens SBP by 20%
what IGg crosses placenta?
IgG maternal immunity
hcg
human chorionic gonadotropin maintains corpus luteum
maintains uterine lining and stim. mammary glands
estrogen
stimulates mammary glands, gives fetus energy
placental lactogen
mimics GH, promote maternal insulin resistance and high blood glucose
placental lactogen
softens cervix and weakens pubic symphysis
relaxin
complciations of relaxin
pelvic pain y
double jointedness
3 main vascular changes
decreased tone
decreased SVR by 20%
vena cava compression
2 blood changes
blood volume increase by 50-100%
RBC mass increase 25-40%
anemia relative - dilutional
t/f placenta keeps acth and cortisol levels high
true
release of ACTH triggers
release of POMC
= hyperpigmentation of pregnancy
linea nigra, melisma
CO dramatically…mester
increases during 2nd and 3rd tri 35+%
by
decreases during post partum 6 mo
BV
increases a ton 2 and 3rd tri
by 30+%
HR increases
2nd and 3d tri
by 10-15%
SV
increases in 2nd and 3rd by about 10%
by 8 wks gestation mom cardiac changes underway t/f?
true
changes in maternal pump
cardiac axis displaced cephalad and left
PMI elevated and lateral
Left axis deviation
t//f preggers have increase in dysrhythmias
true
to hypokalemia may be part of this due to increased mineral corticoid activity
during contractions SVR increases by..
10-15%
PVR decreases by
34%
78 in pregnant and 119 in not pregnant
CO increases by
43%
why does SVR increase during labor?
autotransfusions 300-500cc
labor causes SNS overdrive = increase constriction
blood is squeezed back into central circulation during contractions
in general uterus is at the pelvic brim by__wks
12
uterus is to the umbilicus at
20wks
renin is stimulated by __ and __
progesterone and placenta
increased renin means what 3 things
increased sodium absorption, potassium excretion and water retention (6-8L)
leads in increase in blood volume
with high blood volume what renal changes do you see?
GFR increases by 50%
dilution of plasma proteins = lower colloid oncotic pressure = increase edema
hydroureter due to
progesterone relax peristaltic ureter muscles
uterus obstrunction leads to slow down on right
urinary stasis = dilation
complications of hydroureter
dilation renal pelvices, calyce
increased kidney size
__ diameter increases by 2 cm and circumference by 5-7cm
transverse thorax
increased min. ventilhation
tidal volume increases with pregd by
30-40%
FRC is reduce by ___ due to ?
20% due to smaller lung size at end of respiration
3 resp changes
less IRV l
larger tidal vol
smaller residual vol
ph changes
compensated respiratory alkalosis
at placenta: more co2 exits fetal circ.
more co 2 exhealed per min
6 main GI changes
- slower motility - progesterone
- LES relax
- increased clot risk
- increased GB stones
- variation free hormone levels
- vomiting
what causes HEG
HCG
highest point of HCG
9-12 wks
HEG is more common with multipreg why?
more placentas = more HCG
___mimics TSH
HCG
HCG increases T3/T4 which leads to
nausea
if TSH level abnormal in 1st tri check t3/t4 and then..
recheck in 2nd tri
3 main ortho changes
- altered center of gravity
- altered gait
- greater joint laxatiy
why spider angiomata and palmar erythema?
increased CO
maternal glucose crosses placenta by __
diffusion baby gets more glucose
higher mom’s glucose = more insulin baby makes
neonates of DM moms become hypoglycemic post birth due to..
too much insulin
3 areas baby stores glucose
liver, trunk and shoulders
higher prevalence of gestation DM in what races
Hispanic, AA, NA, Asian and pacific islander
fetal gestational DM complication with bile
hyperbilirubinemia
t/f all preg should screen for gestation dm
true
gestation screen occurs at __wks
24-28wks
screen for gestation dm early?
yes if pt has RF: BMI over 30, hx
if early gestation screen is normal..
repeat screen at 24-28wks
test for gestation dm
give 50 gm sugar wait 1 hr - check
if abnormal 3hr GTT or FBS at 2 hr
preggers more susceptible to
CMV, HSV, Varicella, Malaria
pregnancy decrease sx of autoimmune dz t/f
true
what is included in torch titer
Toxoplasmosis Other Rubella CMV HSV
dz bad if preggers get for kid
toxoplasmosis hep B syphilis varicella rubella rubeola CMV HSV
across all tri this ifxn can cause still birth
toxoplasmosis
most severe in 1st tri
raw meat or cat feces
varicella most dang in 1st tri may cause
life threatening dz for infant
has 50% rate of malformation
hearing loss, deafness, blind, heart and neuro, mental retardation
rubella
t/f cmv part of herpes family
true
mental retardation, hydrocephalus, microcephaly blind, deaf
CMV
if occur in first tri try abx
HSV 1 or 2
blind, MR..death if ll1st outbreak with preg
HSV encephalopathy
check lesions prior delivery
varicela can cause
infant encephalopathy
maternal PNA
CMV risk
retinitisis
HIV risk
perinatal transmission
parvovirus B19 risk
fetal hydrops
syphillis
PTL, PTD, IUGR, fetal hydrops
group b strep
GBS PNA or sepsis