Preclin and Diseases - Study Flashcards

1
Q

John, 18yr old. Blurry vision with 3 month old glasses. OD -6/-2.5x90 (6/9.5), OS -5.50/-4.00x85 (6/12). Previous optometrist only checked prescription and kept changing over last 3 visits.

What specific questions would you ask during history taking?

A
  • LOFTSEA (location, onset, frequency, type/severity, self-treatment, exacerbating factors, associated symptoms)
  • is blurry vision in both eyes? is it constant? What is the onset? anything makes it better/worse?
  • anyone in family with high prescription, blindness, eye diseases?
  • history of atopy (allergies)? eye rubbing?
  • last full eye test?
  • general health, medications?
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2
Q

John, 18yr old. Blurry vision with 3 month old glasses. OD -6/-2.5x90 (6/9.5), OS -5.50/-4.00x85 (6/12). Previous optometrist only checked prescription and kept changing over last 3 visits.

What specific screening tests will you perform for this patient? Explain why these tests are chosen

A

VA - overall indication of visual function
Pupils - neurological issues?
B.V (CT, NPA, NPC) – young patient, BV issues may give rise to blurry vision
Oc. Motil. - muscle balance/neurological issues
Confrontation - extent of FOV
CV Ishihara - male px: higher probability of CVD
Keratometry/Topography - high cyl, complains of frequent change in Rx

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3
Q

John reads 2/15 plates (OU) on the Ishihara. Describe how you can further evaluate his colour vision

A

Stage 1 (detection): Ishihara (RG), Lanthony (BY), Farnsworth (BY), Richmond HRR (RG and BY), City University (RG and BY)

Stage 2 (assess type/severity): Farnsworth D15, Lanthony desaturated D15, H16, Farnsworth Munsell M 100 hue, Oscar/Medmont C100

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4
Q

Describe in greater detail the process of diagnosing CVD

A

Start with detection (using ishihara, richmond, city uni, farnsworth f2 or lanthony album). A pass means normal or very mild CVD. If they fail detection: Farnsworth D15.

If pass Farnsworth D15: Do Lanthony desaturated D15, pass that = very mild defect, fail that = mild CVD)

If fail Farnsworth D15: then moderate/severe CVD. Do H16 test (pass = moderate, fail = severe). Also do Medmont C-100 to determine if protan or deutan

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5
Q

You suspect the px has keratoconus. Describe 3 techniques that you will perform and the signs that you will expect to observe.

A

Retinoscopy - scissors reflex
Keratometry and/or Topography - distorted K mires, steep cornea
Slit lamp exam - cornea thinning, prominent cornea nerves, munsun’s sign

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6
Q

John, 18yr old. Blurry vision with 3 month old glasses. OD -6/-2.5x90 (6/9.5), OS -5.50/-4.00x85 (6/12). Previous optometrist only checked prescription and kept changing over last 3 visits.

You decide to examine posterior eye. Between direct ophthalm, fundus and/or BIO, which technique/s do you choose? Explain

A

DFE (dilated fundus exam) indicated as px is high myope - increased risk of peripheral retinal abnormalities
Once dilated - perform both fundus lens (detailed view of ONH, BVs, Macula) and BIO (to look at peripheral abnormalities)

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7
Q

What are your instructions to the patient in a dilated fundus exam?

A

“I am going to have a look at the back of your eye to ensure that it’s healthy. This will involve shining a light into your eye. I will also need to put some drops in your eyes so we can have a thorough examination. These drops will make your pupils bigger and will blur your vision for a few hours. Things will get a bit blurry and the sun may be a bit glare-y. Did you drive today? Did you bring your sunglasses? Do you know if you are allergic to any drops?”

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8
Q

John, 18yr old. Blurry vision with 3 month old glasses. OD -6/-2.5x90 (6/9.5), OS -5.50/-4.00x85 (6/12). Previous optometrist only checked prescription and kept changing over last 3 visits.

You dilated the patient. What specific features might you expect to see in the fundus?

A
  • peripheral retinal tears/detachment, retinal holes, retinal degeneration (high myopes have higher risk)
  • “white without pressure”: white patches in the periphery (happens for myopes)
  • vitreous detachment
  • tigroid fundus (myopia/degenerative myopia)
  • choroidal/scleral crescent
  • peripapillary atrophy (assoc. degenerative myopia)
  • tilted disc? (assoc. with high astig)

So basically other than tilted disc, all these fundus signs are associated with high myopia (I guess KC doesn’t have many fundus signs in that case)

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9
Q

What does white without pressure mean?

A

You know how when you press your skin you get a white patch. It’s like this but in the eye and without pressure. White patches on the eye’s periphery

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10
Q

Explain how tigroid fundus occurs

A

as the eye enlarges (myopia), the RPE thins, resulting in a tessellated (checkered) appearance of the fundus and increased visibility of the choroidal vasculature

you get patches of bright dark bright (hence checkered)

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11
Q

You observed a feature on the BIO in the px’s left eye when he is looking up and towards to the ear. Which part of the retina is the feature located? How is the examiner and 20D lens oriented relative to the px?

A
  • Superior temporal retina
  • Examiner view from down and towards px’s nose
  • Lens held perpendicular to examiner’s view
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12
Q
27 year old female with gritty sensation in right eye. It happened last night and is getting worse.
Findings: 
VA: R 6/6 L 6/6+, N5@40cm
CT: D+N: OrthoP, NPC: TTN, NPA: R+L 8D
Confrontation + motility NAD
  1. List any questions that may assist you in your management (4 questions sufficient)
A
  1. Do you have dry eyes?
  2. Do you wear contact lenses? is grittiness same with/without?
  3. Any injury or trauma to the eye? (foreign bodies)
  4. Do you experience any pus or discharge coming from your eye
  5. Are there any eye drops that make it better?
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13
Q
27 year old female with gritty sensation in right eye. It happened last night and is getting worse.
Findings: 
VA: R 6/6 L 6/6+, N5@40cm
CT: D+N: OrthoP, NPC: TTN, NPA: R+L 8D
Confrontation + motility NAD
  1. How would you investigate this further?
A

Slit lamp:

  • fluoroscene staining with cobalt blue check TBUT
  • lid eversion
  • anterior chamber reaction: look for cells and flare

Pupil testing (could be irregular due to trauma)

Posterior segment examination (w/dilation. Assuming VH over 1 or normal gonio)

(half mark for tonometry to measure IOP)

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14
Q
27 year old female with gritty sensation in right eye. It happened last night and is getting worse.
Findings: 
VA: R 6/6 L 6/6+, N5@40cm
CT: D+N: OrthoP, NPC: TTN, NPA: R+L 8D
Confrontation + motility NAD
  1. List your differentials and provide your provisional diagnosis
A

condition is unilateral and getting worse - therefore is progressive

  • probably not dry eye (b/c it’s progessive)
  • could be CL infection (b/c they can be unilateral)
  • could be FB, trauma or infection (b/c progressive/getting worse)
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15
Q
27 year old female with gritty sensation in right eye. It happened last night and is getting worse.
Findings: 
VA: R 6/6 L 6/6+, N5@40cm
CT: D+N: OrthoP, NPC: TTN, NPA: R+L 8D
Confrontation + motility NAD

How would you manage this patient?

A
  • eye drops if dry eye (probably not dry eye though)
  • if CL issue: stop using the contact lenses
  • review px at later time
  • if superficial FB: remove it (via referral to ophthalm)
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16
Q

You suspect a patient has glaucoma. What methods/techniques could you use to assess for this?

A

VA: to check progression of disease (open-angle tends to have good v.a in initial stages, whereas closed-angle will notice blurry vision)
Visual Field test: (check for typical gluacoma peripheral loss) - confrontation, red cap (check optic nerve, glaucoma can damage it)
Tonometry: check IOP (high in glaucoma, except NTG)
VH and Gonio: assess angle.
DFE: only if angle is ok! (if not just do undilated fundus)
- check for C/D ratio (large may imply glaucoma), NRR rim thinning, peripapillary atorphy, optic disc hemorrhage
- central corneal thickness: patients with thin corneas may show artificially low IOP readings
- OCT

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17
Q

Why would you check visual fields in a suspected glaucoma patient even though their v.a was fine?

A

because glaucoma involves peripheral visual field loss

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18
Q

When do you always do both fundus and BIO together?

A

When you dilate the eye

19
Q

You suspect a patient has diabetic retinopathy. What methods/techniques can you use to assess for this?

A

DFE (or FE) - look for neovascularisation and hard exudates
VH/Gonio - prior to any dilation you do
slit lamp - check lens for sugar cataract (associated condition, 1/2 mark from kwang for sure)
- check visual field (to see if any spots in vision)
- every test ever because diabetes ruins everything (check that pdf on DR again)
- maybe pelli robson also to check for sugar cataract

20
Q

List symptoms of Diabetic Retinopathy

A
spots or dark strings
floaters
blurred vision
fluctuating vision
impaired colour perception
dark or empty areas in your vision
vision loss
21
Q

Patient complains about central vision loss, you suspect AMD. What tests might you do?

A
  • Amsler (central field test) (see if missing/wavy)
  • fundus (look for drusen i guess, and neovascularisation for wet AMD)
  • check vitreous clear. Something may be blocking their central view from the vitreous
  • vision loss may be neurological? check pupils then (AMD has been associated with relative afferent pupillary defects)
  • possibly do ishihara because AMD colour perception changes (richmond HRR)
22
Q

Patient comes to you with night blindness. You suspect Retinitis Pigmentosa. What tests do you do?

A
  • Visual Field (check for tunnel vision)
  • contrast sensitivity (RP have reduced CS)
  • BIO + fundus (check for floaters i.e. ret detachment)
  • maybe check for cataract as well b/c why not

In fundus look for: pigmentary deposits (initially in peripheral retina), attenuation of retinal vessels, waxy pallor of optic disc, various degrees of retinal atrophy)

23
Q

Name 5 symptoms for Diabetic Retinopathy (note: assuming px already has diabetes. Otherwise maybe consider the symptoms being a reason for something else)

A
  • blurry vision
  • eye strain
  • vision loss + dark spots + blindness
  • floaters
  • poor night vision

And yes px should have diabetes first before we consider DR.

24
Q

What type of secondary complications could diabetic retinopathy result in?

A
  • retinal detachment

- macular oedema

25
Q

How do you treat proliferative diabetic retinopathy and wet amd?

A

Anti-VEGF medication to reduce neovascularisation

26
Q

Name 5 symptoms for Age-Related Macular Degeneration (AMD)

A
  • poor night vision
  • reduced VA
  • distorted vision
  • reduced contrast sensitivity
  • central vision loss

Note: mainly we’d consider AMD in patients who are older, so be on the lookout for age of patient (age 50 and over is a good bet)

27
Q

List 3 symptoms for Retinitis Pigmentosa (RP)

A
  • night blindness
  • loss of peripheral vision (i.e. tunnel vision)
  • possible sensitivity to light and glare
28
Q

Do cataract patients show sensitivity to glare?

A
  • yes
29
Q

A patient comes in complaining about red eyes, What tests/techniques can you do?

A
  • ask about allergies, contact lenses, conjunctivitis, foreign body sensation, gritty, sore, makeup
  • check for pronounced inferior sulci (due to lack of sleep) [also check lids to see if droopy, lack of sleep]
  • check with slit lamp for foreign bodies (can use indirect for this)
  • chronic dry eye can cause redness. Check meibomian glands for MGD and do lid eversion. Check tear break up time
  • if itchy eyes, check for lice on lashes with slit lamp
  • (don’t do tonometry b/c possible infection)
  • (cease CL use b/c might cause further irritation if cause)
30
Q

You are testing a patient’s visual acuity but it keeps changing/fluctuating. What tests might you do?

A
  • check accommodative function and do BV tests. Px may have accommodative excess, whose symptoms are variable VA, lead/no lag, and fails +ve facility
  • check for corneal integrity and keratometry. KC patients can fluctuate in their vision (I know this very well). Try pinhole.
31
Q

Patient has dry eye. What tests would you consider performing?

A
  • check meibomian glands
  • lid eversion: check for ectropian (eyelid turned away from eyeball). can cause dry eye and can make your eyes feel gritty, dry, sandy, irritation
  • TBUT
  • check slit lamp with lissamine for lid wiper epitheliopathy
  • check if px is blinking properly. Px blinking may be impaired in bell’s palsy (3rd nerve palsy)
  • in that case if neuro, check pupils
  • dry eye could be sjogren’s syndrome (t-cell infiltration of lacrimal gland leading to inability to secrete tears) if chronic. If px has dry mouth too that is also a symptom. Refer for blood tests in that case
32
Q

A patient comes into your clinic saying they see floaters. What may you suspect and what tests can you do?

A
  • retinal detachment
  • high myopia
  • could be physiological (if been there for a long time like whole life)

Fundus signs of high myopia:

  • tigroid fundus
  • retinal degen, tears, holes
  • vitreous detachment
  • choroidal/scleral crescent
  • peripapillary atrophy
33
Q

Name 6 factors that could increase the risk of floaters (found online):

A
  • age over 50
  • high myopia
  • eye trauma
  • complications from cataract surgery
  • diabetic retinopathy
  • eye inflammation
34
Q

Patient comes in with blurred vision. You looked out their genetics somehow and saw mutation of OPA1 gene. What do you suspect/know, and how can you test this?

A
  • Dominant Optic Atrophy
  • do fundus exam: saucerisation of disc, C/D ratio greater than 0.5, peripapillary atrophy and sectoral palor of optic nerve
  • could also do red cap test, because optic nerve affected
35
Q

How does smoking influence the risk of developing AMD?

A

increases it

36
Q

List 3 clinical symptoms for Myaesthenia Gravis:

A
  • lid ptosis
  • diplopia (often vertical)
  • fatigue on repeated effort (e.g. more ptosis after blinking many times in a row)
37
Q

What (super clinical) clinical tests can we use to test for Myaesthenia Gravis:

A

Tensilon/edrophonium chloride testing
or
Single Fibre Electromyography (SFEMG)

38
Q

What are the ocular manifestations of myotonic dystrophy (leads to inability to relax muscle): [5]

A
  • lid ptosis and fatigue
  • cataracts
  • pigment epithelium dystrophy
  • retinal degeneration
  • ciliary body dysfunction
39
Q

What 3 secondary conditions can moderate to high degrees of hyperopia cause?

A
  • binocular disorders

- risk of convergent strabismus and ambylopia developing in infancy

40
Q

What secondary condition as a result of aging causes myopia in the geriatric population?

A

Cataracts

41
Q

List the major symptoms of Sjogren’s Syndrome. Also what is sjogren’s syndrome?

A

t-cell infiltration of lacrimal gland leading to the inability to secrete tears.

Dry eyes: burning, stinging, itchy, gritty, sore, red, swollen, discomfort when looking at lights, sticky eyelids when you wake up, blurred vision, symptoms may be worse when air is dry

Dry mouth: feels like food stuck in throat, hoarse voice, change in food taste, dry skin at corners of lips, dental issues such as ulcers

note: anti-inflammatory’s and prescription eye drops can help

42
Q

What are the functional ocular consequences of Stickler Syndrome?

A
  • vitreous abnormalities
  • retinal degeneration/tears/breaks
  • cataracts
  • glaucoma
  • high myopia

note: people with stickler syndrome tend to have a flatter face. People with Stickler have higher risk of retinal detachment. Stickler is a heriditary connective tissue disease

43
Q

List 5 ophthalmic complications that could arise due to diabetic retinopathy

A
  • corneal abnormalities
  • glaucoma
  • iris neovascularisation
  • cataracts
  • neuropathies
44
Q

What conditions are contrast sensitivity tests used to screen for?

A

visual pathway disorders:

  • optic neuritis and multiple sclerosis
  • parkinson’s
  • papilloedema
  • primary open angle glaucoma
  • diabetic retinopathy
  • compressive lesions

(note also: AMD, macular oedema and cataract generally cause greater loss at medium to low spatial frequencies, so VA may still be good. This can be considered a hidden loss to vision)