Pre-Operative Antacids Flashcards

1
Q

What is the normal dosage of Na⁺ Citrate (Bicitra)

A

15 - 30 mls

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2
Q

How does Bicitra work?

A

Non-particulate neutralization of gastric pH

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3
Q

What is the downside of Bicitra?

A
  • ↑ Na⁺
  • ↑ gastric volume
  • ↑ gastric pH
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4
Q

What are the H2 antagonists used in the operating room?

A
  • Famotidine
  • Ranitidine
  • Cimetidine
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5
Q

What is the most potent H2 antagonist?

A

Famotidine

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6
Q

What is the dose of Famotidine?

A

20 mg IV

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7
Q

What is a major downside to famotidine usage?

A

Inhibition of phosphate absorption → hypophosphatemia

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8
Q

What is the major downside to cimetidine use?

A

CYP450 inhibition

Consider warfarin, phenytoin, TCA’s, etc..

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9
Q

What is the dose of cimetidine?

A

150 - 300 mg IV

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10
Q

What is the dose of Ranitidine?

A

50mg/20mls over 2 min

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11
Q

What effects do PPI’s have on anticoagulants?

A
  • Inhibited warfarin metabolism = ↑ INR
  • Inhibition of Plavix = ↓ PLT function
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12
Q

What is the IV dose of pantoprazole?

A

40 mg / 100 mls over 2 min

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13
Q

What is the IV dose of omeprazole?

A

40 mg / 100mls over 30 min

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14
Q

What is the PO dose of omeprazole?

A

40 mg → 3 hours prior to surgery

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