Pre-natal neonata Flashcards
What is morgani hernia ?
they are a form of CDH anteriorly, USUALLY quite benign but can present as an obstruction?
What age do the alveolar ducts completely form at ?
8 years of age
Fetal hydatoin syndrome: cleft lip and palate, small nose, hypertelorism and hypolastic extremities and nails is associated with which medication during pregnancy ?
Phenytoin ( Dilantin)
As per CPS statement:
Well appearing term baby > 37 wks
with-positive mothers with adequate intrapartum antibiotic prophylaxis (IAP), no additional risk factors OR mothers who are GBS-negative or GBS-unknown status, with one other risk factor and adequate IAP:
Recommendation: observe for 24 hours, and no work up to be done
Ebstein anomalie, fetal goitre, hypotonia, arrythmia and seizures are associated with which exposure during pregnancy ?
Lithium
What would the 1st trimester screen be if + for T. 21?
T. 18 ?
- T21 -> > 3.5MM IN nuchal transuluency,
- PAPP-A - (reduced in T21)
- hcg - normal or increased - T18
hcg -decreased
pappa - normal
Syndrome associated with micropenis, increased risk of testicular cancer or breast cancer, could appear TALL ie. marfans (1)
Kleinfelters
Test karyotype
what is the treatment for graves disease and hyperthyroidism ?
methimazole
and symtompatic ie. beta blocker
you see a baby with:
cutis aplasia
cleft lip palate (mid line defects)
polydactyly
What syndrome are you thinking of ?
What is the work up and mangement ?
Patau ( t. 13)
work up ? -confirm testing with karyotype -MRI head, us echo, audio -renal US
80 % of of intussception occur before age? true or false
True
If you were concerned about a) t21 ? or t18 what would you expect.
1.T21 - AFP- low estriol-low -hcg -high -inhibin A - high
- T18
-afp - low
-estriol low
hcg- low
What is you ddx for a distal obstruction ie. bile emesis
- meconium ileus
- Hirshsprungs
- Ileal atresia
4.
Quad screen (15 to 22 wk), involves which markers ? (4)
- AFP
- Estriol
- Hcg
- inhibin A
As per CPS statement:
For GBS-positive mothers with inadequate IAP and no additional risk factors OR mothers who are GBS-negative or GBS-unknown status, with one other risk factor and inadequate IAP:
close obs of vitals and examination before discharge
You see a baby with: cutis aplasia -hypertonia -rocker bottom feet -clenched fists -CHD
What syndrome are you thinking of ?
What is the work up and management ?
Edward (t.18)
confirmatory karyotype
Echo
Abdo US
AS PER CPS statement
For un well term baby - what do you do ?
full septic work up and amp/ gent work up
What anomalies are associated with IDM ?
- LGA
- IUGR
- birth trauma thus cerebral edema
- symptomatic hypoglycemia - neuroimpact
- hypoglycemia, hypocalcemia
- congenital anomalies: cardiological
- hematology: polycythemia
- congenital anomalies: DA, atresia of the bowel. left colon syndrome
Rewiew of GIR CALCULATIONS
D10W = 10 g per 100 mL
1 mL has 10/100 = 0.1 g = 100 mg dextrose
To calculate in mg/kg/min convert time units
100 mg/mL x 60 mL/kg/d ÷ 24 h per day ÷ 60 min per hour
=4.2 mg/kg/min
Which type of twins is most at risk for TTTS ?
MCDA (15%)
MCMA (5)
where would you feel the mass in intussception ?
upper adbdomen
This syndrome is associated with the RAS/MAPK pathway and involves mutation in multiple genes ?
Auto dominant inheritance, FTT but can have risk of of heap
Noonan syndrome
Thus what are some features to screen for ? -growth, thus gh -cv management ie right sided lesions -tx for coagulopathies
Abnormal fluid accumulation in ≥2 fetal compartments Skin thickening Fetal ascites Pleural effusion Pericardial effusion (±)Polyhydramnios is reffered to ?
Hydrops fetalis
How can you miss a mechel in a tech 99 ?
when it is behind the bladder
In what population of mothers is neonatal lupus highest risk ?
any with a autoimmune disease
