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Anesthesia rotation review > Pre-med drugs > Flashcards

Pre-med drugs Flashcards

1
Q

MOA of anticholinergics

A

Class of drug that inhibits the paraysmpathetic nervous system. It antagonizes the muscarinic acetylcholine receptors.

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2
Q

Anticholinergic common drugs

A

Atropine, Glycopyrrolate

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3
Q

MOA of alpha2 agonists

A

competitive agonist of alpha2 adrenergic receptors

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4
Q

A2 adrenergic receptor function

A

…

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5
Q

Effects of A2 agonists (major effects)

A

Sedation, analgesia, reduced stress response, muscle relaxation, strong vasoconstriction, mild resp. depression

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6
Q

A2 agonist drugs

A

Xylazine, Dexmedetomidine, Medetomidine, detomidine, Romifidine

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7
Q

A2 antagonists (reversals)

A

Atipamezole, Yohimbine, Tolazoline

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8
Q

Phenothiazines MOA

A

Antagonists of multiple receptors (Dopamine, serotonin, alpha1, histamine)

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9
Q

Phenothiazines major effects

A

sedation, antiemetic, mild respiratory depression, vasodilation

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10
Q

Phenothiazine drugs

A

Acepromazine

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11
Q

Butyrophenones MOA

A

similar to phenothiazine??

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12
Q

Butyrophenones major effects

A

sedative, vasodilation, antiemetic

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13
Q

butyrophenones drug

A

Droperidol, azeperone (stresnil)

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14
Q

Benzodiazepines MOA

A

GABA receptor agonists.

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15
Q

GABA receptor function

A

The main inhibitory neurotransmitter in the CNS

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16
Q

Benzodiazepine major effects

A

sedative, anticonvulsant, muscle relaxation

17
Q

Benzodiazepines agonist drugs

A

Diazepam, Midazolam, Zolazepam (Zoletil or Telazol)

18
Q

Benzodiazepine antagonists (reversal)

A

Flumazenil, Sarmazenil

19
Q

Opioid receptors

A

mu (strong analgesia, resp depression, dependency), kappa (weaker analgesia), sigma (weak analgesia human)

20
Q

Opioids general major effects

A

Analgesia, MAC sparing, dysphoria, vomiting

21
Q

Full mu agonists (drugs)

A

Morphine, hydromorphone, oxymorphone, Methadone, Fentanyl, Remifentanil

22
Q

Mixed opioid antag/anogists

A

Butrophanol (mu antagonist, kappa agonist)

23
Q

partial or weak mu agonists

A

Buprenorphine (partial), tramadol (comes from metabolite)

24
Q

Opioid antagonists

A

Naloxone, Naltrexone

25
Q

Centrally acting muscle relaxants

A

Guaifenesin

26
Q

Peripherally acting muscle relaxants

A

NMBDs, Dantrolene

Anesthesia rotation review (2 decks)

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