Pre-invasive disease Flashcards
1
Q
Risk factors for cervical dysplasia and cancer
A
Smoking Multiple sexual partners (HPV) Socioeconomic status OCP use Immunosuppression - solid organ transplant recipients or HIV+
2
Q
What is HPV?
A
Double stranded DNA virus interacts with tumour suppression genes (p53) and leads to reduced cell apoptosis and increased cell proliferation
3
Q
Which are the “low risk” HPV?
A
6 and 11
4
Q
Which are the “high risk” HPV
A
16, 18, 31
