Pre-analytical sampling and sample handling

Question 1

What is pre-analytics?

Answer 1

all determining factors/processes which influence a specimen before it is analysed in the lab. This includes specimen collection, transport and sample processing

Question 2

What is haemolysis?

Answer 2

The breakage of RBC membrane and causes release of intra-cellular components haemoglobin into surrounding fluid.

Question 3

what are the causes of haemolysis?

Answer 3

results from certain health conditions
improper specimen collection and vigorous handling
prolonged tourniquet time
difficult venepuncture/poor blood flow

Question 4

what does haemolysis result in?

Answer 4

pink/red tinge to the serum or plasma. this can lead to inaccurate results and specimen rejection by the laboratory

Question 5

what are the routes of lab acquired infections?

Answer 5

inhalation
ingestion via hand/mouth contact 
absorption through cuts and grazes
inoculation by sharps injuries
contact between mucous membranes and contaminated materials