Pre-analytic Considerations Flashcards
Begins when a test is ordered and ends when testing begins. This testing process, if not properly adressed, can lead to errors.
Preanalytical or pre-examination phase
Results used for comparison become a range of value with high and low limits
reference range or reference interval
Refers to the resting metabolic state of the body early in the morning after fasting for approx. 12 hours
Basal State
ideal for establishing reference ranges on inpatients because the effects of diet, exercise, and other controllable factors on test results are minimized or eliminated
basal-state specimen
Physiological variable that affects values of rbc and wbc as well as kidney function
age
A physiological variable that concerns higher elevations and sea level
altitude
RBC count that have higher reference ranges at higher elevations
hemoglobin and hematocrit
analytes that increase at higher elevations
c-reactive protein and uric acid
analytes that decrease in value at increased altitude
urinary creatinine
occurs with persistent vomitting or diarrhea that causes hemoconcentration
dehydration
a condition in which blood components that cannot easily leave the bloodstream become concentrated in the smaller plasma volume
hemoconcentration
a physiological variable where blood analyte composition can be altered by the ingestion of food and drink
diet
how many hours are patients typically asked to fast
approx. 8 to 12 hours
Analytes that are elevated in patients on high-protein diets
ammonia, urea, and uric acid levels
Analytes that increase with the consumption of beverages with caffeine
cortisol and ACTH levels
Analytes affected by excessive drinking amounts of water and other fluids
hemoglobin (hgb) levels
Analytes that increases with ingestion of food such as butter, cheese, cream, and etc.
lipid levels
increased blood lipid content
lipemia
specimen containing high levels of lipids
lipemic
a physiological variable that includes cariations or fluctuations. Factors would be posture, activity, eating, daylight and darkness, being awake or asleep, and etc.
Diurnal/circadian variation
a drug therapy that can cause decrease in blood cells, especially WBCs and platelets
chemotherapy durg