PRACTICE TEST 1, 2 & 3 Flashcards
WHAT TYPE OF TESTING DOES THE
BLOOD BANK TECHNOLOGIST PERFORM
WHEN DETERMINING BLOOD GROUP
OF A PATIENT?
A. Genotyping
B. Phenotyping
C. Both genotyping and phenotyping
D. Polymerase Chain Reaction
B. Phenotyping
WHICH OF THE FOLLOWING IS TRUE?
A. An individual with the AB genotype is homozygous
for A and B
B. An individual with the BO genotype is homozygous
for B
C. An individual with the OO genotype is
heterozygous for O
D. An individual with the BB genotype is homozygous
for B
D. An individual with the BB genotype is
homozygous for B
WHICH GENOTYPE IS HETEROZYGOUS
FOR C?
A. DCE/DCE
B. Dce/dce
C. dCE/dCe
D. Dce/dCe
D. Dce/dCe
WHICH GENOTYPE(S) WILL GIVE RISE TO THE BOMBAY PHENOTYPE?
A. HH only
B. HH and Hh
C. hh only
D. Hh and hh
C. hh only
LEXIE’S BLOOD TYPE IS AB. WHICH OF THE FOLLOWING DESCRIBES THE EXPRESSION OF MOST BLOOD GROUP ANTIGENS? A. Dominant B. Codominant C. Recessive D. Corecessive
B. Codominant
MEREDITH’S BLOOD TYPE IS AO AND HER HUSBAND, DEREK IS BO. WHAT BLOOD TYPE IS NOT POSSIBLE FOR THEIR OFFSPRING? A. AB B. A OR B C. O D. ALL ARE POSSIBLE
D. ALL ARE POSSIBLE
THE ALLEGED FATHER OF A CHILD IN A DISPUTED CASE OF PATERNITY IS BLOOD GROUP AB. THE MOTHER IS GROUP O AND THE CHILD IS GROUP O. WHAT TYPE OF EXCLUSION IS THIS? A. Direct/primary/ first order B. Random C. Probabiity D. Indirect/ secondary/ second order
D. Indirect/ secondary/ second order
IgM ANTIBODIES HAVE THE ABILITY TO
DIRECTLY AGGLUTINATE RBCs AND
CAUSE VISIBLE AGGLUTINATION, WHY
IS THIS SO?
A. IgM antibodies are larger molecules and have the ability to
bind more antigen
B. IgM antibodies tend to clump together more readily to
bind more antigen
C. IgM antibodies are found in greater concentrations than
IgG molecules
D. IgM antibodies are not limited by subclass specificity
A. IgM antibodies are larger molecules and have the ability
to bind more antigen
RANJIT’S SERUM IS INCOMPATIBLE WITH O CELLS.
HIS RBCs GIVE A NEGATIVE REACTION TO ANTI-H
LECTIN. WHAT IS THE MOST LIKELY CAUSE OF THESE
RESULTS?
A. The patient may be a subgroup A
B. The patient may have an immunodeficiency
C. The patient may be a Bombay individual
D. The patient may have developed alloantibodies
C. The patient may be a Bombay individual
WHAT ANTIBODIES ARE FORMED BY A BOMBAY INDIVIDUAL? A. Anti-A and Anti-B B. Anti- A,B C. Anti- A, anti-B and anti-H D. Anti-H
C. Anti- A, anti-B and anti-H
ACQUIRED B ANTIGENS HAVE BEEN FOUND IN? A. Group A persons B. Bombay individuals C. Group O D. All blood groups
A. Group A persons
A PATIENT’S RBC FORWARD TYPES AS GROUP O BUT
THE SERUM AGGLUTINATES B CELLS (4+). YOUR
NEXT STEP WOULD BE?
A. Extend reverse typing for 15 mins
B. Perform an antibody screen, including a room temperature
incubation
C. Incubate washed red cells with Anti-A1 and anti-A,B for
thirty mins at room temperature
D. Test patient’s cells with Dolichos biflorus
C. Incubate washed red cells with Anti-A1 and anti-A,B for
thirty mins at room temperature
WHICH BLOOD GROUP HAS THE LEAST AMOUNT OF H ANTIGEN? A. A1B B. A2 C. B D. A1
A. A1B
TED’S GENOTYPE IS Dce/dce. HOW IS HE CLASSIFIED? A. Rh positive B. Rh negative C. Rh null D. Rh stallion
A. Rh positive
TESTING FOR Rh ANTIBODIES ARE USUALLY?? A. IgM B. IgM and IgG C. IgG D. IgA
C. IgG
WHAT TECHNIQUES ARE NECESSARY FOR WEAK D TESTING? A. Saline + 22°C incubation B. Albumin or LISS + 37°C incubation C. Saline + 37°C incubation D. 37°C incubation + IAT
D. 37°C incubation + IAT
PENNY IS SUSPECTED OF HAVING PCH. WHICH
PATTERN OF REACTIVITY IS CHARACTERISTIC OF THE
DONATH-LANDSTEINER ANTIBODY?
A. The antibody attaches to RBCs at 4°C and causes
hemolysis at 37° C
B. The antibody attaches to RBCs at 37° C and causes
agglutination at the IAT phase
C. The antibody attaches to RBCs at 22 ° C and cause
hemolysis at 37° C
D. The antibody attaches to RBCs and causes agglutination at
the IAT phase
A. The antibody attaches to RBCs at 4°C and causes
hemolysis at 37° C
HOW CAN INTERFERING ANTI-P1 ANTIBODY BE REMOVED FROMA MIXTURE OF ANTIBODIES? A. Neutralization with saliva B. Agglutination with human milk C. Combination with urine D. Neutralization with hydatid cyst fluid
D. Neutralization with hydatid cyst fluid
AN ANTIBODY SHOWS STRONG REACTIONS IN ALL TEST
PHASES. ALL SCREEN AND PANEL CELLS ARE POSITIVE. THE
SERUM IS THEN TESTED WITH A CORD CELL AND THE
REACTION IS NEGATIVE. WHAT ANTIBODY IS SUSPECTED?
A. Anti-i
B. Anti-I
C. Anti-H
D. Anti-p
B. Anti-I
WHICH GROUP OF ANTIBODIES ARE COMMONLY FOUND AS COLD AGGLUTININS? A. Anti-K, anti-k and anti-Jsb B. Anti-D, anti-e, anti-C C. Anti- fya, anti-Fyb D. Anti-M and anti-N
D. Anti-M and anti-N
WHICH OF THE FOLLOWING ANTIBODIES CHARACTERISTICALLY GIVES A REFRACTILE MIXED-FIELD APPEARANCE? A. Anti-Sda B. Anti-s C. Anti-K D. Anti-Dia
A. Anti-Sda
An emergency trauma patient requires transfusion. 6 units of blood are ordered stat. because of hypovolemia, blood extraction was difficult and was not able to submit sample. O negative blood is released. When will compatibility testing be performed?
A. Compatibility testing must be performed before blood is
issued.
B. Compatibility testing will be performed when a patient
sample is available
C. Compatibility testing may be performed immediately using
donor serum
D. Compatibility testing is not necessary when blood is
released in emergency situations.
B. Compatibility testing will be performed when a patient sample is available
CAN CROSSMATCHING BE PERFORMED ON OCTOBER 14
USING A PATIENT SAMPLE DRAWN ON OCTOBER 12?
A. Yes, a new sample would not be needed
B. No, a new sample is needed because the 2 day limit has
expired
C. No, a new sample is needed for each testing
D. The discretion is based on the ordering physician
A. Yes, a new sample would not be needed
A MAJOR CROSSMATCH AND SCREENING CELLS ARE 2+ AT
IS, 1+ AT 37°C AND NEGATIVE AT THE IAT PHASE. IDENTIFY
THE MOST LIKELY PROBLEM?
A. Combination of antibodies
B. Cold alloantibody
C. Rouleaux
D. Test error
B. Cold alloantibody
WHAT CORRECTIVE ACTION SHOULD BE TAKEN WHEN ROULEAUX CAUSES POSITIVE TEST RESULTS? A. Perform saline replacement procedure B. Perform an autoadsorption C. Run a panel D. Perform an elution
A. Perform saline replacement procedure
ALL OF THE FOLLOWING ARE REASONS FOR PERFORMING
AN ADSORPTION, EXCEPT?
A. Removal of interfering antibodies
B. Separation of mixtures of antibodies
C. Confirmation of weak antigens on red cells
D. Identification of antibodies causing positive DAT
D. Identification of antibodies causing positive DAT
HOW LONG MUST A RECIPIENT SAMPLE BE KEPT IN THE
BLOOD BANK FOLLOWING COMPATIBILITY TESTING?
A. 3 days
B. 5 days
C. 7 days
D. 10 days
C. 7 days
WHAT ARE THE PRETRANSFUSION REQUIREMENTS FOR AN AUTOLOGOUS TRANSFUSION? A. ABO and Rh typing B. Type and screen C. Major Crossmatch D. All of the above
A. ABO and Rh typing
Patient Sloan is AB+. 2 units of blood have been ordered
by the physician. Currently the inventory shows, 0 AB
units, 10 A+ units, 1 A- unit, 5 B+ units and 20 O+ units.
Which should be set up for the major crossmatch.?
A. A+
B. O+
C. B+
D. Call blood supplier for type specific blood
A. A+
A PATIENT HAD A TRANSFUSION REACTION. THE MT ON DUTY BEGAN THE LABORATORY INVESTIGATION. WHAT SHOULD BE DONE FIRST?
A. Perform DAT on the posttransfusion sample
B. Check for clerical error
C. Repeat ABO and Rh typing of patient and donor unit
D. Perform antibody screen on the post transfusion sample
B. Check for clerical error - major cause of transfusion
related deaths
A PATIENT HAS HEMOLYTIC REACTION TO BLOOD
TRANSFUSED 8 DAYS AGO, WHAT IS THE MOST LIKELY
CAUSE?
A. Immediate, non immunological, probably caused by
volume overload
B. Delayed immunological, probably due to an antibody such
anti Jka
C. Delayed immunological, probably a result of an iron overload
D. Immediate, immunological probably due to a clerical error
B. Delayed immunological, probably due to an antibody such
anti Jka – Kidd antibodies are common cause for HTR
WHAT MAY BE FOUND IN THE SERUM OF A PERSON WHO IS EXHIBITING SIGNS OF TRALI? A. Red blood cell alloantibody B. IgA antibody C. Antileukocyte antibody D. allergen
C. Antileukocyte antibody
THIS TYPE OF TRANSFUSION REACTION OCCURS IN ABOUT
1% OF ALL TRANSFUSIONS AND RESULTS IN A 1°C
TEMPERATURE RISE OR HIGHER. NOT RELATED TO PATIENT
MEDICAL CONDITION?
A. Immediate hemolytic
B. Delayed
C. Febrile nonhemolytic reaction
D. Transfusion related acute lung injury
C. Febrile nonhemolytic reaction
WHAT WOULD BE THE RESULT OF GROUP A BLOOD GIVEN
TO A GROUP O PATIENT?
A. Non immune transfusion reaction
B. Immediate hemolytic transfusion reaction
C. Delayed hemolytic transfusion reaction
D. Febrile nonhemolytic transfusion reaction
B. Immediate hemolytic transfusion reaction
A SHIPMENT OF PACKED RBCs, PLATELETS AND
LEUKOCYTE REDUCED RBCs ARRIVED IN THE SAME
CONTAINER AT 1-6°C. WHAT SHOULD BE DONE?
A. Refrigerator
B. Reject the shipment
C. Prepare the RBCs for freezing
D. Accept red cell products, return or discard the platelets
D. Accept red cell products, return or discard the platelets
A UNIT OF WHOLE BLOOD IS COLLECTED AT 10:00 AM
AND STORED AT 20-24°C. WHAT IS THE LAST HOUR
PLATELET CONCENTRATE MAY BE MADE FROM THIS UNIT?
A. 4:00 PM
B. 6:00 PM
C. 7:00 PM
D. 8:00 PM
B. 6:00 PM - platelets prepared from whole blood must be processed within 8 hours of collections
SHELDON COOPER HAS CHRONIC GRANULOMATOUS DISEASE. WHAT IS THE COMPONENT OF CHOICE FOR THIS PATIENT? A. FFP B. Granulocytes C. Cryoprecipitate D. RBCs
B. Granulocytes
WHAT SHOULD BE DONE IF A NOTICEABLE CLOT IS FOUNF
IN AN RBC UNIT?
A. Issue the unit, the blood will be filtered
B. Issue the unit, note the presence of clot on the release
form
C. Filter the unit in the blood bank before issue
D. Do not issue the unit
D. Do not issue the unit