PRACTICE TEST 1, 2 & 3 Flashcards
WHAT TYPE OF TESTING DOES THE
BLOOD BANK TECHNOLOGIST PERFORM
WHEN DETERMINING BLOOD GROUP
OF A PATIENT?
A. Genotyping
B. Phenotyping
C. Both genotyping and phenotyping
D. Polymerase Chain Reaction
B. Phenotyping
WHICH OF THE FOLLOWING IS TRUE?
A. An individual with the AB genotype is homozygous
for A and B
B. An individual with the BO genotype is homozygous
for B
C. An individual with the OO genotype is
heterozygous for O
D. An individual with the BB genotype is homozygous
for B
D. An individual with the BB genotype is
homozygous for B
WHICH GENOTYPE IS HETEROZYGOUS
FOR C?
A. DCE/DCE
B. Dce/dce
C. dCE/dCe
D. Dce/dCe
D. Dce/dCe
WHICH GENOTYPE(S) WILL GIVE RISE TO THE BOMBAY PHENOTYPE?
A. HH only
B. HH and Hh
C. hh only
D. Hh and hh
C. hh only
LEXIE’S BLOOD TYPE IS AB. WHICH OF THE FOLLOWING DESCRIBES THE EXPRESSION OF MOST BLOOD GROUP ANTIGENS? A. Dominant B. Codominant C. Recessive D. Corecessive
B. Codominant
MEREDITH’S BLOOD TYPE IS AO AND HER HUSBAND, DEREK IS BO. WHAT BLOOD TYPE IS NOT POSSIBLE FOR THEIR OFFSPRING? A. AB B. A OR B C. O D. ALL ARE POSSIBLE
D. ALL ARE POSSIBLE
THE ALLEGED FATHER OF A CHILD IN A DISPUTED CASE OF PATERNITY IS BLOOD GROUP AB. THE MOTHER IS GROUP O AND THE CHILD IS GROUP O. WHAT TYPE OF EXCLUSION IS THIS? A. Direct/primary/ first order B. Random C. Probabiity D. Indirect/ secondary/ second order
D. Indirect/ secondary/ second order
IgM ANTIBODIES HAVE THE ABILITY TO
DIRECTLY AGGLUTINATE RBCs AND
CAUSE VISIBLE AGGLUTINATION, WHY
IS THIS SO?
A. IgM antibodies are larger molecules and have the ability to
bind more antigen
B. IgM antibodies tend to clump together more readily to
bind more antigen
C. IgM antibodies are found in greater concentrations than
IgG molecules
D. IgM antibodies are not limited by subclass specificity
A. IgM antibodies are larger molecules and have the ability
to bind more antigen
RANJIT’S SERUM IS INCOMPATIBLE WITH O CELLS.
HIS RBCs GIVE A NEGATIVE REACTION TO ANTI-H
LECTIN. WHAT IS THE MOST LIKELY CAUSE OF THESE
RESULTS?
A. The patient may be a subgroup A
B. The patient may have an immunodeficiency
C. The patient may be a Bombay individual
D. The patient may have developed alloantibodies
C. The patient may be a Bombay individual
WHAT ANTIBODIES ARE FORMED BY A BOMBAY INDIVIDUAL? A. Anti-A and Anti-B B. Anti- A,B C. Anti- A, anti-B and anti-H D. Anti-H
C. Anti- A, anti-B and anti-H
ACQUIRED B ANTIGENS HAVE BEEN FOUND IN? A. Group A persons B. Bombay individuals C. Group O D. All blood groups
A. Group A persons
A PATIENT’S RBC FORWARD TYPES AS GROUP O BUT
THE SERUM AGGLUTINATES B CELLS (4+). YOUR
NEXT STEP WOULD BE?
A. Extend reverse typing for 15 mins
B. Perform an antibody screen, including a room temperature
incubation
C. Incubate washed red cells with Anti-A1 and anti-A,B for
thirty mins at room temperature
D. Test patient’s cells with Dolichos biflorus
C. Incubate washed red cells with Anti-A1 and anti-A,B for
thirty mins at room temperature
WHICH BLOOD GROUP HAS THE LEAST AMOUNT OF H ANTIGEN? A. A1B B. A2 C. B D. A1
A. A1B
TED’S GENOTYPE IS Dce/dce. HOW IS HE CLASSIFIED? A. Rh positive B. Rh negative C. Rh null D. Rh stallion
A. Rh positive
TESTING FOR Rh ANTIBODIES ARE USUALLY?? A. IgM B. IgM and IgG C. IgG D. IgA
C. IgG
WHAT TECHNIQUES ARE NECESSARY FOR WEAK D TESTING? A. Saline + 22°C incubation B. Albumin or LISS + 37°C incubation C. Saline + 37°C incubation D. 37°C incubation + IAT
D. 37°C incubation + IAT
PENNY IS SUSPECTED OF HAVING PCH. WHICH
PATTERN OF REACTIVITY IS CHARACTERISTIC OF THE
DONATH-LANDSTEINER ANTIBODY?
A. The antibody attaches to RBCs at 4°C and causes
hemolysis at 37° C
B. The antibody attaches to RBCs at 37° C and causes
agglutination at the IAT phase
C. The antibody attaches to RBCs at 22 ° C and cause
hemolysis at 37° C
D. The antibody attaches to RBCs and causes agglutination at
the IAT phase
A. The antibody attaches to RBCs at 4°C and causes
hemolysis at 37° C
HOW CAN INTERFERING ANTI-P1 ANTIBODY BE REMOVED FROMA MIXTURE OF ANTIBODIES? A. Neutralization with saliva B. Agglutination with human milk C. Combination with urine D. Neutralization with hydatid cyst fluid
D. Neutralization with hydatid cyst fluid
AN ANTIBODY SHOWS STRONG REACTIONS IN ALL TEST
PHASES. ALL SCREEN AND PANEL CELLS ARE POSITIVE. THE
SERUM IS THEN TESTED WITH A CORD CELL AND THE
REACTION IS NEGATIVE. WHAT ANTIBODY IS SUSPECTED?
A. Anti-i
B. Anti-I
C. Anti-H
D. Anti-p
B. Anti-I
WHICH GROUP OF ANTIBODIES ARE COMMONLY FOUND AS COLD AGGLUTININS? A. Anti-K, anti-k and anti-Jsb B. Anti-D, anti-e, anti-C C. Anti- fya, anti-Fyb D. Anti-M and anti-N
D. Anti-M and anti-N
WHICH OF THE FOLLOWING ANTIBODIES CHARACTERISTICALLY GIVES A REFRACTILE MIXED-FIELD APPEARANCE? A. Anti-Sda B. Anti-s C. Anti-K D. Anti-Dia
A. Anti-Sda
An emergency trauma patient requires transfusion. 6 units of blood are ordered stat. because of hypovolemia, blood extraction was difficult and was not able to submit sample. O negative blood is released. When will compatibility testing be performed?
A. Compatibility testing must be performed before blood is
issued.
B. Compatibility testing will be performed when a patient
sample is available
C. Compatibility testing may be performed immediately using
donor serum
D. Compatibility testing is not necessary when blood is
released in emergency situations.
B. Compatibility testing will be performed when a patient sample is available
CAN CROSSMATCHING BE PERFORMED ON OCTOBER 14
USING A PATIENT SAMPLE DRAWN ON OCTOBER 12?
A. Yes, a new sample would not be needed
B. No, a new sample is needed because the 2 day limit has
expired
C. No, a new sample is needed for each testing
D. The discretion is based on the ordering physician
A. Yes, a new sample would not be needed
A MAJOR CROSSMATCH AND SCREENING CELLS ARE 2+ AT
IS, 1+ AT 37°C AND NEGATIVE AT THE IAT PHASE. IDENTIFY
THE MOST LIKELY PROBLEM?
A. Combination of antibodies
B. Cold alloantibody
C. Rouleaux
D. Test error
B. Cold alloantibody
WHAT CORRECTIVE ACTION SHOULD BE TAKEN WHEN ROULEAUX CAUSES POSITIVE TEST RESULTS? A. Perform saline replacement procedure B. Perform an autoadsorption C. Run a panel D. Perform an elution
A. Perform saline replacement procedure
ALL OF THE FOLLOWING ARE REASONS FOR PERFORMING
AN ADSORPTION, EXCEPT?
A. Removal of interfering antibodies
B. Separation of mixtures of antibodies
C. Confirmation of weak antigens on red cells
D. Identification of antibodies causing positive DAT
D. Identification of antibodies causing positive DAT
HOW LONG MUST A RECIPIENT SAMPLE BE KEPT IN THE
BLOOD BANK FOLLOWING COMPATIBILITY TESTING?
A. 3 days
B. 5 days
C. 7 days
D. 10 days
C. 7 days
WHAT ARE THE PRETRANSFUSION REQUIREMENTS FOR AN AUTOLOGOUS TRANSFUSION? A. ABO and Rh typing B. Type and screen C. Major Crossmatch D. All of the above
A. ABO and Rh typing
Patient Sloan is AB+. 2 units of blood have been ordered
by the physician. Currently the inventory shows, 0 AB
units, 10 A+ units, 1 A- unit, 5 B+ units and 20 O+ units.
Which should be set up for the major crossmatch.?
A. A+
B. O+
C. B+
D. Call blood supplier for type specific blood
A. A+
A PATIENT HAD A TRANSFUSION REACTION. THE MT ON DUTY BEGAN THE LABORATORY INVESTIGATION. WHAT SHOULD BE DONE FIRST?
A. Perform DAT on the posttransfusion sample
B. Check for clerical error
C. Repeat ABO and Rh typing of patient and donor unit
D. Perform antibody screen on the post transfusion sample
B. Check for clerical error - major cause of transfusion
related deaths
A PATIENT HAS HEMOLYTIC REACTION TO BLOOD
TRANSFUSED 8 DAYS AGO, WHAT IS THE MOST LIKELY
CAUSE?
A. Immediate, non immunological, probably caused by
volume overload
B. Delayed immunological, probably due to an antibody such
anti Jka
C. Delayed immunological, probably a result of an iron overload
D. Immediate, immunological probably due to a clerical error
B. Delayed immunological, probably due to an antibody such
anti Jka – Kidd antibodies are common cause for HTR
WHAT MAY BE FOUND IN THE SERUM OF A PERSON WHO IS EXHIBITING SIGNS OF TRALI? A. Red blood cell alloantibody B. IgA antibody C. Antileukocyte antibody D. allergen
C. Antileukocyte antibody
THIS TYPE OF TRANSFUSION REACTION OCCURS IN ABOUT
1% OF ALL TRANSFUSIONS AND RESULTS IN A 1°C
TEMPERATURE RISE OR HIGHER. NOT RELATED TO PATIENT
MEDICAL CONDITION?
A. Immediate hemolytic
B. Delayed
C. Febrile nonhemolytic reaction
D. Transfusion related acute lung injury
C. Febrile nonhemolytic reaction
WHAT WOULD BE THE RESULT OF GROUP A BLOOD GIVEN
TO A GROUP O PATIENT?
A. Non immune transfusion reaction
B. Immediate hemolytic transfusion reaction
C. Delayed hemolytic transfusion reaction
D. Febrile nonhemolytic transfusion reaction
B. Immediate hemolytic transfusion reaction
A SHIPMENT OF PACKED RBCs, PLATELETS AND
LEUKOCYTE REDUCED RBCs ARRIVED IN THE SAME
CONTAINER AT 1-6°C. WHAT SHOULD BE DONE?
A. Refrigerator
B. Reject the shipment
C. Prepare the RBCs for freezing
D. Accept red cell products, return or discard the platelets
D. Accept red cell products, return or discard the platelets
A UNIT OF WHOLE BLOOD IS COLLECTED AT 10:00 AM
AND STORED AT 20-24°C. WHAT IS THE LAST HOUR
PLATELET CONCENTRATE MAY BE MADE FROM THIS UNIT?
A. 4:00 PM
B. 6:00 PM
C. 7:00 PM
D. 8:00 PM
B. 6:00 PM - platelets prepared from whole blood must be processed within 8 hours of collections
SHELDON COOPER HAS CHRONIC GRANULOMATOUS DISEASE. WHAT IS THE COMPONENT OF CHOICE FOR THIS PATIENT? A. FFP B. Granulocytes C. Cryoprecipitate D. RBCs
B. Granulocytes
WHAT SHOULD BE DONE IF A NOTICEABLE CLOT IS FOUNF
IN AN RBC UNIT?
A. Issue the unit, the blood will be filtered
B. Issue the unit, note the presence of clot on the release
form
C. Filter the unit in the blood bank before issue
D. Do not issue the unit
D. Do not issue the unit
WHAT COMPONENT IS INDICATED FOR PATIENTS WHO HAVE ANTI IgA antibodies? A. Whole blood B. Packed RBC C. Washed or deglycerolized RBCs D. Granulocyte concentrate
C. Washed or deglycerolized RBCs
WHAT COMPONENT MAY NOT BE PREPARED IF WHOLE BLOOD IS SPUN AT 1-6°C? A. Packed RBCs B. Platelets C. Leukocyte-reduced RBC D. FFP
B. Platelets
HOW SHOULD UNITS OF PLATELETS CONCENTRATE?
A. At room temperature, lying horizontally
B. At 35-36°C, with constant agitation
C. Stored upright, at 20-24°C away from direct sunlight
D. 20-24°C with constant agitation
D. 20-24°C with constant agitation
WHAT PERCENTAGE OF RED CELLS MUST BE RETAINED IN LEUKOCYTE-REDUCED RED CELLS? A. 80% B. 75% C. 85% D. 50%
C. 85%
WHAT COMPONENTS MAY BE SHIPPED TOGETHER WITH FFP? A. Frozen RBCs and cryoprecipitate B. Platelets C. Packed RBCs and granulocytes D. Double red cell
A. Frozen RBCs and cryoprecipitate
WHICH COMPONENT HAS THE LONGEST EXPIRATION DATE? A. Cryoprecipitate B. FFP C. Frozen RBCs D. Platelet concentrate
C. Frozen RBCs
WHAT IS THE EXPIRATION TIME OF CRYOPRECIPITATE ONCE POOLED USING AN OPEN SYSTEM? A. 4 hours B. 6 hours C. 8 hours D. 24 hours
A. 4 hours
WHAT IS THE EXPIRATION TIME OF CRYOPRECIPITATE ONCE POOLED USING AN CLOSED SYSTEM? A. 4 hours B. 6 hours C. 8 hours D. 24 hours
B. 6 hours – if closed system
WHICH OF THE FOLLOWING INDIVIDUALS IS ACCEPTABLE AS A BLOOD DONOR?
A. 29 years old man who received the hepatitis B vaccine last
week
B. 21 year old woman who has had nose pierced last week
C. 30 year old man who lived in Palawan for years and
returned to Tacloban last month
D. 54 year old man who tested positive for HCV
A. 29 years old man who received the hepatitis B vaccine last week
WHAT SHOULD BE DONE WHEN A WOMAN WHO IS 24
WEEKS PREGNANT HAS A POSITIVE ANTIBODY SCREEN?
A. Perform an antibody identification panel, titer if
necessary
B. No need to do anything until 30 week AOG
C. Administer RhIg prophylactically
D. Adsorb the antibody onto antigen-positive cells
A. Perform an antibody identification panel, titer if
necessary
KERNICTERUS IS CAUSED BY THE EFFECT OF? A. Anemia B. Unconjugated bilirubin C. Antibody specificity D. Antibody titer
B. Unconjugated bilirubin
ALL OF THE FOLLOWING TESTS ARE ROUTINELY PERFORMED ON A CORD BLOOD SAMPLE, EXCEPT? A. Forward typing ABO B. Antibody screen C. Rh typing D. DAT
B. Antibody screen
WHAT MARKER IS THE FIRST TO APPEAR IN HEPATITIS B INFECTION? A. Anti-HBc (IgM) B. HbsAg C. Anti-HBs D. Anti-HBc (IgG)
B. HbsAg
ALL OF THE FOLLOWING ARE REQUIRED TESTS ON DONOR BLOOD,EXCEPT? A. HBsAg B. Anti CMV C. Anti HIV D. Anti HTLV I/II
B. Anti CMV
THIS TYPE OF ANTIBODY RESPONSE IS ANALOGOUS TO AN ANAMNESTIC ANTIBODY REACTION? A. Primary B. Secondary C. Tertiary D. anaphylactic
B. Secondary
Which of the following would be a cause for deferral? A. Temperature of 37 ° C B. Pulse rate of 97 bpm C. BP of 110/70 D. Hematocrit level of 37%
D. Hematocrit level of 37%
Which of the following would not be a cause for permanent deferral? A. Individual living in Palawan B. Positive hepatitis C test result C. Positive HTLV-I antibody D. Positive anti-HBc result
A. Individual living in Palawan
Immunization for rubella would result in a temporary deferral for? A. 4 weeks B. 8 weeks C. 6 months D. 1 year
A. 4 weeks
Once thawed FFP must be transfused within? A. 4 hours B. 6 hours C. 8 hours D. 24 hours
D. 24 hours
1 unit of whole blood raises the hemoglobin \_\_ and hematocrit \_\_? A. 2 g/dL – 2% B. 1 g/dL – 3 % C. 5 g/dL – 3% D. 2 g/dL – 1 %
B. 1 g/dL – 3 %
Which of the following lists the correct shelf-life for the component A. Deglycerolized RBCs – 24 hours B. RBC (CPD) – 35 days C. Platelet concentrate – 7 days D. FFP – 5 years
A. Deglycerolized RBCs – 24 hours
Mary recently received a live attenuated vaccine for typhoid, her deferral should be A. 6 months B. 3 months C. 2 weeks D. 4 weeks
C. 2 weeks
You are the intern assigned to interview
a potential donor. He disclosed that he
currently takes Ciprofloxacin. What
should you do
A. Donor is permitted to donate
B. Neglect this information and proceed with donation
C. Defer Temporarily and advise donor to complete his
prescription
D. Defer temporarily, instruct donor to stop meds and come
back the following day for donation
C. Defer Temporarily and advise donor to complete his
prescription
Ross had a severe burn injury 10
months ago and needed skin grafting,
will he be able to donate blood?
A. Yes, because being a recipient of skin graft is not a
contraindication to blood donation
B. Temporary deferral for 3 months
C. Temporary deferral for 12 months after the skin graft
procedure
D. Permanent deferral because there is already a break in skin
barrier that may foster bacterial growth and sepsis
C. Temporary deferral for 12 months after the skin graft
procedure
What is the minimum hemoglobin requirement for an autologous donor? A. 12 g/dL B. 11 g/dL C. 10 g/dL D. 11.5 g/dL
B. 11 g/dL
The most common anticoagulant used in apheresis ? A. Acid citrate dextrose B. EDTA C. Heparin D. Any of the above
A. Acid citrate dextrose
Which of the following can be given to an apheresis donor to increase the number of circulating granulocytes? A. DDAVP B. Hydroxyethyl starch C. Immune globulin D. G-CSF
D. G-CSF
Whole blood using ACD has a shelf-life of? A. 35 days B. 21 days C. 42 days D. 30 days
B. 21 days
Blood component of choice for patients who are immunocompromised, such as chemo patients? A. RBCs irradiated B. Whole blood C. Packed RBCs D. Sedimented RBCs
A. RBCs irradiated
A potential donor takes aspirin as his
maintenance medication, is he a
suitable donor for platelet pheresis?
A. Yes, this medication does not affect platelet activity
B. No, this medication inhibits platelet function
B. No, this medication inhibits platelet function
Of the following, which blood type is selected when a patient cannot wait for ABO-matched RBCs? A. A B. B C. O D. AB
C. O
Irradiated granulocytes are stored at _ with a shelf life ? A. 1-6 °C , 2 weeks B. -18 °C, 1 year C. 20-24 °C, 24 hours D. 20-24 °C, 5 days
C. 20-24 °C, 24 hours
Which fluid should be used to dilute RBCs? A. 0.9% saline B. 5% dextrose C. Immune globulin D. Lactated Ringer’s solution
A. 0.9% saline
Considered as the leading cause of transfusion related fatalities? A. TRALI B. Bacterial infection C. ABO incompatibility D. STD through blood transfusion
A. TRALI
Transfusion reactions are classified according to? A. Signs or symptoms presenting during or after 24 hours B. Immune or non immune C. Infectious or non infectious D. All of the above
A. Signs or symptoms presenting during or after 24 hours
TRALI present with the following? A. Respiratory distress B. Severe hypoxemia and hypotension C. Fever D. All of the above
D. All of the above
A patient had the following lab results after work
up for a transfusion reaction, DAT +, decreased
hemoglobin, increased LDH, increased bilirubin,
decreased haptoglobin?
A. Acute immune mediated hemolytic transfusion reaction
B. Acute nonimmune mediated hemolytic transfusion
reaction
C. Febrile nonhemolytic transfusion reaction
D. TRALI
A. Acute immune mediated hemolytic transfusion reaction
What component is most frequently involved with transfusion associated sepsis? A. Plasma B. PRBC C. Platelets D. Wholeblood
C. Platelets
Fatal transfusion reactions are mostly caused by? A. Serologic errors B. Improper storage of blood C. Clerical errors D. Improper handling of the product
C. Clerical errors
Which of the following is characteristic of iron over load? A. Delayed, nonimmune complication B. Chelating agents are used C. Multi organ damage may occur D. All of the above
D. All of the above
RhIg is indicated in which of the following circumstances? A. Mother D positive, infant D-positive B. Mother D-negative, infant D-positive C. Mother D- positive, infant D-negative D. Mother D-negative, infant D-negative
B. Mother D-negative, infant D-positive
Which of the following blood groups reacts best with an anti-H? A. O B. A1 C. B D. A2
A. O
What is the confirmatory test for syphilis? A. RPR B. VDRL C. FTA-ABS D. Any of the above
C. FTA-ABS
The hemoglobin/hematocrit level of an allogenic blood donor should be atleast? A. 12.5 g/dL, 38% B. 12 g/dL, 37% C. 13 g/dL, 42% D. 10.5 g/dL, 36%
A. 12.5 g/dL, 38%
Considered as a marker for high infectivity? A. HBeAg B. HBsAg C. Anti HBs D. Anti HBe
A. HBeAg
An ABO type on a patient gives the ff rxns:
Forward
Anti-A = 4+
Anti-B = 4+
Reverse
A1 cells= (-)
B cells = (-)
A. O
B. A
C. B
D. AB
D. AB
The major immunoglobulin class(es) of anti B in a group A individual is are? A. Ig M B. Ig G C. Ig M and Ig G D. IgM and Ig A
A. Ig M
The immunodominant sugar responsible for blood group A
specificity
A. L-fucose
B. N-acetyl-D-galactosamine
C. D-galactose
D. Uridine diphosphate N-acetyl-D-galactose
B. N-acetyl-D-galactosamine
An ABO type on a patient gives the ff. rxns:
ptx cells w/
Anti-A= 4+
Anti-B= 4+
ptx serum w/
A1 cells = 2+
B cells = (-)
A. A1 with acquired B
B. A2B with anti-A1
C. AB with increased concentrations of protein in serum
D. AB with an autoantibody
B. A2B with anti-A1
Category of ABO discrepancy wherein there is unexpected reactions in the reverse grouping A. Group I discrepancy B. Group II discrepancy C. Group III discrepancy D. Group IV discrepancy
A. Group I discrepancy
Rh antibodies react best at what temperature A. 22°C B. 18°C C. 15°C D. 37°C
D. 37°C
Convert (rr) Weiner nomenclature to Fisher-race nomenclature A. DCe/dce B. dce/dce C. DcE/DcE D. dCe/dce
B. dce/dce
Which of the following characteristics best describes
Lewis antibody
A. IgM, naturally occuring, caused HDFN
B. IgM, naturally occuring, do not cause HDFN
C. Ig G, in vitro hemolysis, cause hemolytic transfusion reaction
D. Ig, G, in vitro hemolysis, do not cause hemolytic transfusion reaction.
B. IgM, naturally occuring, do not cause HDFN
Which blood group system is associated with resistance to P.vivax malaria A. P B. Kell C. Duffy D. Kidd
C. Duffy
Which of the following blood groups are known for showing dosage A. I B. P C. Kidd D. Lutheran
C. Kidd
Which antibody is a commonly associated with delayed hemolytic transfusion reaction A. Anti-s B. Anti- k. C. Anti-Lua D. Anti-Jka
D. Anti-Jka
McLeod syndrome includes the following clinical manifestations, except A. Abnormal RBC morphology B. Neurological abnormalities C. Muscular abnormalities D. None of the above
D. None of the above
A weakly reactive antibody with a titer of 128 is neutralized
by plasma. Which of the following could be the specificity
A. Anti-JMH = John Milton Hagen system
B. Anti-Ch = Chido/Rodgers system
C. Anti-Kna = Knops System
D. Anti-Kpa= Kell system
B. Anti-Ch = Chido/Rodgers system