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BLOOD BANK > ADD NOTES > Flashcards

ADD NOTES Flashcards

1
Q

What is the SAMPLE & REAGENT used for forward typing?

A

patient red blood cells + Anti-sera reagents (Anti-A and Anti-B)

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2
Q

What is the SAMPLE & REAGENT used for reverse typing?

A

patient serum + reagent A cells and reagent B cells

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3
Q

physical expression of a genotype

A

PHENOTYPING

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4
Q

example AO but phenotypes as Group A

A

GENOTYPE

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5
Q

having 2 identical alleles of a particular gene or

genes

A

HOMOZYGOUS

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6
Q

the presence of 2 different alleles at a particular

gene locus.

A

HETEROZYGOUS

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7
Q

Represents the inheritance of a double dose of the h gene (hh) & its RBCs do not react with the anti-H lectin (Ulex eropaeus)

A

BOMBAY PHENOTYPE Oh

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8
Q

Occurs if the child expressed an antigen that he could not have inherited from
the potential father.

A

DIRECT EXCLUSION

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9
Q

Occurs when a genetic marker is absent in the child but should have been
transmitted by the alleged father

A

INDIRECT EXCLUSION

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10
Q

seen only in Group A individuals.

associated with??

A

acquired B

colorectal malignancy, GI obstruction, gram-negative
sepsis

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11
Q

At what pH does not agglutinate acquired B cells?

A

pH of 6.0

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12
Q

Serves as a source for Anti-A1 reagent. This is used to differentiate A1 from A2 phenotypes

A

Dolichus biflorus

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13
Q

Arrange the Ag from greatest to least?

A

O > A2 > B > A2B > A1> A1B

Greatest Least

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14
Q

Most Rh antibodies are ____ immunoglobulins and react optimally at _____

A

Ig G, 37C

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15
Q

ABO blood group system has naturally occurring antibodies that are
primarily ____

A

Ig M

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16
Q

If C is in trans position

A

C in Trans to RHD

17
Q

D antigens expressed are complete but fewer in number

A

Weak D

18
Q

D antigen expression is weakened when one or more D epitopes within the entire D protein is either missing or altered.

A

Partial D

19
Q

Individuals whose RBC possess an extremely low number of D antigen sites.

A

Del

20
Q

has anti-P specificity with biphasic activity

A

Donath-Landsteiner

21
Q

In Donath-Landsteiner the antibody attaches to RBCs at ___ and then causes the red cells to hemolyze
when warmed to ____

A

4C, 37C

22
Q

contain mostly I antigen, and anti I would react with all _____ found on screen or panels cells.

A

Adult cells (2)

23
Q

contain mostly i antigen and would test negative or only weakly positive with anti I

A

Cord cells

24
Q

Compatibility testing may be performed on a patient sample ____ of the scheduled transfusion

A

w/n 3 days

25
Q

“stacks of coins” appearance of RBCs

CAUSES?

A

Rouleaux formation

Causes: increased serum proteins like fibrinogen and globulins

26
Q

this term refers to removing or “dissociation”of an antibody that is attached to the surface of an RBC.

A

Elution

27
Q

adherence of an antibody or antigen onto the surface of an RBC.

A

Adsorption

28
Q

associated with antibodies to human leukocyte antigens or neutrophil antigens that react with patient granulocytes causing acute respiratory insufficiency.

A

TRALI

29
Q

Patients with ____ cannot fight bacterial infection because of dysfunctional phagocytic enzymes

A

CGD

30
Q

Patients with _____ antibodies should not receive components containing plasma.

A

anti-IgA

31
Q

prospective donor is unable to donate blood for

a limited period of time

A

Temporary deferral

32
Q

Prospective donor is unable to donate blood for
someone else for an unspecified period of time due to current
regulatory requirements

A

Indefinite deferral

33
Q

Prospective donor will never be eligible to

donate blood for someone else.

A

Permanent deferral

34
Q

enhances the separation of white cells from the red cells

A

Hydroxyethyl starch

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