Practice quiz content Flashcards

1
Q

Which genetic diseases are caused by an increase in the number of nucleotides in the DNA of the affected gene or it’s upstream region?

A

Huntington disease and Fragile X Syndrome

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2
Q

Which type of Down Syndrome results in a karyotype of 45 chromosomes?

A

Down Syndrome due to translocation

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3
Q

What is the normal function of RB proteins?

A

Binds to protein E2F to prevent the cell from entering S phase

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4
Q

What is the normal function of MLH1 proteins?

A

Corrects DNA base-pair mismatches

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5
Q

What is the normal function of BRCA1 proteins?

A

repairs DNA or triggers apoptosis

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6
Q

What is the normal function of VHL proteins?

A

controls angiogenesis

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7
Q

What is the difference between DNA sequence mutations and epigenetic modifications?

A

epigenetics modifications can be reversed

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8
Q

What does nondisjunction during gametogenesis refer to?

A

the failure of the chromosomes to separate during production of sperm and egg

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9
Q

What does epigenetics play an important role in?

A

cellular differentiation, heterochromatin maintenance, and X chromosome inactivation

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10
Q

Which hormones increase during ACUTE stress?

A

Epi and NE

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11
Q

What hormone levels increase during prolonged stress?

A

Human growth hormone, cortisol, epi, glucagon, T3 and T4, NE

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12
Q

What is the most commonly reported symptom of cancer treatment?

A

fatigue

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