Practice Quiz - Alt Of Endo Function 2 Flashcards
What is the cause of Type 1 DM?
Autoimmune response that targets the beta cells in the pancreas
The symptom of glycosuria in DM is best explained by which of the following mechanisms?
The transport maximum for glucose reabsorption is reached which stimulates the process of osmotic diuresis
An acute insulin deficiency causes potassium to shift into cells resulting in hypoalkemia
False - presence of insulin stimulates glucose uptake into cells = hyperglycemia
Why do individuals with type 1 DM produce ketones
Insulin deficiency leads to the breakdown of fat/lipids in adipose tissue
Bobby Davies, 12 y.o. Male, newly diagnosed with type 1 DM. His blood glucose level is 280 mg/dL (normal is 70-110 mg/dL). The signs and symptoms of DM you would expect Bobby to exhibit include:
Polydipsia and polyuria
Which of the following is a risk factor for hypoglycemia among type 1 diabetics?
Taking insulin and not eating
Can result in hypoglycemia
Type 1 diabetics who experience repeated episodes of hypoglycemia often miss the early warning signs of hypoglycemia because:
The early autonomic warning signs are not activated
19 y.o. Susan Lee has type 1 DM. She is admitted to the hospital with lab values of: plasma glucose 500 mg/dL (high); urine glucose 4+ (high); arterial pH 7.20 (low). Her parents state that she has been sick with the “flu” for a week. Which of the following statements best explains her circumstances?
The stress of her viral illness has caused ketoacidosis
Type 1 DM is mainly a result of genetics, whereas the causes of type 2 diabetes are mainly environmental.
False
The pathophysiology of type 2 DM involves:
Down regulation of insulin receptors
In addition to hyperglycemia, what other condition often develops in type 2 diabetics?
Dyslipidemia
Which of the following pathophysiological features is present in the hyperosmolar hyperglycemic nonketotic syndrome (HHNKS)?
Profound dehydration
Management of DM involves measuring glycosylated hemoglobin (hemoglobin A1c) levels. The purpose of this test is to:
Monitor long-term glucose control
Chronic complications of type 1 and 2 DM such as retinopathy and nephropathy are primarily related to:
Chronic, uncontrolled hyperglycemia