Practice Quiz - Alt Of Endo Function 2 Flashcards

1
Q

What is the cause of Type 1 DM?

A

Autoimmune response that targets the beta cells in the pancreas

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2
Q

The symptom of glycosuria in DM is best explained by which of the following mechanisms?

A

The transport maximum for glucose reabsorption is reached which stimulates the process of osmotic diuresis

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3
Q

An acute insulin deficiency causes potassium to shift into cells resulting in hypoalkemia

A

False - presence of insulin stimulates glucose uptake into cells = hyperglycemia

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4
Q

Why do individuals with type 1 DM produce ketones

A

Insulin deficiency leads to the breakdown of fat/lipids in adipose tissue

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5
Q

Bobby Davies, 12 y.o. Male, newly diagnosed with type 1 DM. His blood glucose level is 280 mg/dL (normal is 70-110 mg/dL). The signs and symptoms of DM you would expect Bobby to exhibit include:

A

Polydipsia and polyuria

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6
Q

Which of the following is a risk factor for hypoglycemia among type 1 diabetics?

A

Taking insulin and not eating

Can result in hypoglycemia

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7
Q

Type 1 diabetics who experience repeated episodes of hypoglycemia often miss the early warning signs of hypoglycemia because:

A

The early autonomic warning signs are not activated

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8
Q

19 y.o. Susan Lee has type 1 DM. She is admitted to the hospital with lab values of: plasma glucose 500 mg/dL (high); urine glucose 4+ (high); arterial pH 7.20 (low). Her parents state that she has been sick with the “flu” for a week. Which of the following statements best explains her circumstances?

A

The stress of her viral illness has caused ketoacidosis

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9
Q

Type 1 DM is mainly a result of genetics, whereas the causes of type 2 diabetes are mainly environmental.

A

False

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10
Q

The pathophysiology of type 2 DM involves:

A

Down regulation of insulin receptors

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11
Q

In addition to hyperglycemia, what other condition often develops in type 2 diabetics?

A

Dyslipidemia

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12
Q

Which of the following pathophysiological features is present in the hyperosmolar hyperglycemic nonketotic syndrome (HHNKS)?

A

Profound dehydration

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13
Q

Management of DM involves measuring glycosylated hemoglobin (hemoglobin A1c) levels. The purpose of this test is to:

A

Monitor long-term glucose control

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14
Q

Chronic complications of type 1 and 2 DM such as retinopathy and nephropathy are primarily related to:

A

Chronic, uncontrolled hyperglycemia

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