Practice Questions

Question 1

CD4 and CD8 are expressed on B cells and NK cells

A. True
B. False

Answer 1

B. False

Question 2

Is natural killer cell characterized as a lymphocyte?

A. True
B. False

Answer 2

A. True

Question 3

What are the cytokine functions on target cells?

A. Affect cell behavior
B. Mitosis
C. Differentiation
D. Induce protein synthesis
E. All of the above
F. None of the above

Answer 3

E. All of the above

Question 4

Cytokines must bind to their receptors on target cells in order to trigger an Intracellular signal

A. True
B. False

Answer 4

A. True

Question 5

For the purpose of co stimulation the CD28 on T cell binds to … on a professional antigen presenting cell

A. B7 family of molecules
B. CD80 and CD86
C. CD4
D. CD8
E. CD3

Answer 5

A. B7 family of molecules

B. CD80 and CD86

Question 6

Two main features of an antigen are:

A. Size and chemical nature
B. Immunogenicity and antigenicity
C. Foreignness and degradability
D. Physical form and size

Answer 6

B. Immunogenicity and antigenicity

Question 7

By far the largest group of antigens in nature

A. Proteins
B. Lipids
C. Lipopolysaccharides
D. Nucleic acids

Answer 7

A. Proteins

Question 8

T-dependent antigens:

A. Stimulate CD8+ T cells to kill virus infected cells
B. Stimulate dendritic cells to migrate into infected tissues
C. Stimulate B cells to produce antibodies with the help of CD4+ helper
T cells
D. Stimulate B cells directly to induce cytokine production

Answer 8

C. Stimulate B cells to produce antibodies with the help of CD4+ helper T cells

Question 9

T-independent antigens:

A. Have a monomeric structure, I.e., the antigenic determinant occurs
only once
B. Activate B cells oligoclonally
C. Have a polymeric structure I.e., the same antigenic determinant
repeats several times
D. Are not processed by antigen presenting cells

Answer 9

C. Have a polymeric structure I.e., the same antigenic determinant repeats several times

Question 10

Superantigens are named so because:

A. They are the largest type of antigens
B. They can stimulate all types of lymphocytes
C. They can stimulate a large number of CD4+ T cells with different
antigen specificities
D. They only stimulate cytotoxic T cells

Answer 10

C. They can stimulate a large number of CD4+ T cells with different antigen specificities

Question 11

What are haptens?

A. Incomplete antigens because they lack immunogenicity
B. They are antigens with a hollow structure
C. They are independent antigens
D. They are molecules that create an immune response when attached to proteins

Answer 11

A. Incomplete antigens because they lack immunogenicity

D. They are molecules that create an immune response when attached to proteins

Question 12

T cell help for antibody production:

A. Depends on T cell recognition of native antigen bound to B cell
surface Ig
B. Depends on T cell recognition of antigen processed by the B cells
and presented through MHC class II
C. Involves class I MHC on the B cell
D. Can occur in X-irradiated mice
E. Is a feature of the antibody response to pneumococcal polysaccharide SIII

Answer 12

B. Depends on T cell recognition of antigen processed by the B cells and presented through MHC class II

Question 13

These are molecules/receptors that can regulate the lymphocyte function:

A. Cytokines
B. Antibodies
C. Complement
D. Antigen
E. All of the above

Answer 13

E. All of the above