practice Q's

Question 1

Which pair is NOT a set of antithetical antigens?

Jsa/Jkb
E/e
Fya/Fyb
M/N

Answer 1

Jsa/Jkb

Question 2

A donor unit caused a delayed transfusion reaction where a patient developed an anti-Jsa. Given expected antigen frequencies, what is the likely population the donor is from?

Caucasian
Asian
Black
Hispanic

Answer 2

Black

Question 3

Which set of antigens are inherited on the same chromosome?

MNS and P/Glob
Kell and Kidd
Duffy and Rh
Lutheran and ABO

Answer 3

Duffy and Rh

Question 4

If my patient has an unexpected antibody causing a reverse type discrepancy, which antibody am I LEAST likely to suspect?

I
M
P
s

Answer 4

s

Question 5

Due to it being the second most immunogenic blood group system (besides Rh) which blood group am I giving phenotypically matched cells to sickle cell patients?

Duffy
Kidd
Kell
Lutheran

Answer 5

Kell

Question 6

Match the blood group system with the disease associated with it.

Duffy Malaria Vivax
Kidd Delayed Hemolytic Transfusion Reaction
Rh Hydrops Fetalis
P/Glob Paroxysmal Cold Hemoglobinuria

Answer 6

Duffy Malaria Vivax
Kidd Delayed Hemolytic Transfusion Reaction
Rh Hydrops Fetalis
P/Glob Paroxysmal Cold Hemoglobinuria

Question 7

A patient has an antibody reactive with 8 out of 10 cells at room temperature. It is enzyme resistent and neutralized by cyst fluid. Which antibody do you suspect?

anti-N
anti-P1
anti-P1PPk
anti-IH

Answer 7

anti-P1

Question 8

How many panel cells containing E antigen need to demonstrate a positive agglutination reaction with the unknown antibody in order to statistically rule-in anti-E?

1
2
3
4

Answer 8

3

Question 9

What would you call the procedure where you mix patient plasma and patient cells, then read/grade reactions at IAT phase?

Phenotype
DAT
Auto Control
Antibody ID

Answer 9

Auto Control

Question 10

(Multiple options available) Choose which circumstance does NOT require phenotype testing.

An Rh negative patient with a newly identified anti-D
Recently transfused patient with a known anti-Fya
Units for a patient with known anti-K
Units for a patient with a low incident antibody

Answer 10

Units for a patient with a low incident antibody
Recently transfused patient with a known anti-Fya
An Rh negative patient with a newly identified anti-D

Question 11

(Choose all that apply) An antibody is clinically significant when:

It may cause transfusion reaction
It does not cause HDN
It is high incident
It is identified as an HTLA

Answer 11

It may cause transfusion reaction