Class review Flashcards

1
Q

Which
antibody is
NOT known
to fix
compliment?

A. anti-Jka
B. anti-P
C. anti-B
D. anti-k

A

D. anti-k

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2
Q

Which
antithetical
pair is NOT a
high/low
incidence
pair?

A. Lua/Lub
B. Dia/Dib
C. Fya/Fyb
D. K/k

A

C. Fya/Fyb

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3
Q

Which
antibody is
known to
demonstrate
dosage?

A. anti-Jka
B. anti-P
C. anti-Lea
D. Anti-U

A

A. anti-Jka

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4
Q

Which
antigen system
is the entry
point for
Plasmodium
Falciparum?

A. MNS
B. Lutheran
C. Duffy
D. Rhesus

A

A. MNS

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5
Q

Secretor status is
coded on
chromosome 19,
which of the
following systems is
also on this
chromosome?

A. Kell
B. Duffy
C. Lutheran
D. P/Glob

A

C. Lutheran

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6
Q

Which
antigen system
is involved in
urea transport
in the cell?

A. Duffy
B. Kell
C. Kidd
D. P

A

C. Kidd

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7
Q

Which
antibody is
associated with
paroxysmal cold
hemoglobinuria?

A. anti-P1
B. anti-P
C. anti-M
D. Anti-I

A

B. anti-P

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8
Q

Which
antibody
classically gives
mixed field
agglutination
reactions?

A. anti-Lea
B. anti-Lub
C. anti-I
D. Anti-D

A

B. anti-Lub

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9
Q

Which
antibody is
considered a
warm acting
antibody?

A. anti-M
B. anti-N
C. anti-S
D. Anti-Lua

A

C. anti-S

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10
Q

Which
phenotype is
NOT a null
phenotype?

A. Jk3-
B. U-
C. Fy(a-b-)
D. k-

A

D. k-

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11
Q

Which antibody
is most commonly
associated with
delayed hemolytic
transfusion
reactions?

A. anti-s
B. anti-k
C. anti-Lua
D. Anti-Jka

A

D. Anti-Jka

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12
Q

Which of
the
following phen
otypes may
make an allo-
anti-U?

A. M+N+S+s-
B. M+N-S-s-
C. M-N+S-s+
D. M+N-S+s+

A

B. M+N-S-s-

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13
Q

Which
phenotype is
considered
homozygous?

A. R1r”
B. Fy(a+b+)
C. Jk(a-b+)
D. K+k+

A

C. Jk(a-b+)

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14
Q

Your facility has
a rule to not
phenotype units for
antigens that are
<10% prevalent in
the population.
Which clinically
significant antibody
might they miss?

A. E
B. Lea
C. S
D. K

A

D. K

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15
Q

Which duffy
phenotype is
prevalent in the
black population but
nearly non-existent
in caucasians?

A. Fy(a+b+)
B. Fy(a+b-)
C. Fy(a-b+)
D. Fy(a-b-)

A

D. Fy(a-b-)

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16
Q

Which
antigen of the
Kell system is
more frequent
in the black
population?

A. K
B. Kpa
C. Jsa
D. Jka

A

C. Jsa

17
Q

Which
antibody is
produced by
the p null
phenotype?

A. anti-p
B. anti-P
C. anti-P1
D. Anti-PP1Pk

A

D. Anti-PP1Pk

18
Q

Which
antigen is
created by the
transferase
that competes
with Pk
transferase?

A. I
B. N
C. Lea
D. H

A

D. H

19
Q

Which
antigen is NOT
strongly
expressed at
birth in cord
blood?

A. K
B. I
C. Fya
D. M

A

B. I

20
Q

Which
antigen
activity is
enhanced with
treatment
with enzymes?

A. MN
B. Duffy
C. Rh
D. None of them

A

C. Rh

21
Q

Which
antigen would
NOT be found
on glycophorin
B?

A. M
B. N
C. S
D. s

A

A. M

22
Q

Which red
cell morphology
occurs
commonly when
Kell antigens are
missing from the
red cell surface?

A. Spherocytes
B. Acanthocytes
C. Hypochromasia
D. Resistence to lysis in 2M
urea

A

B. Acanthocytes

23
Q

How many
units should you
test to find 2
compatible
blood units for a
patient who has
an anti-Fya?

A. 1
B. 3
C. 5
D. 10

A

C. 5

24
Q

How many units
should you test to
find 1 compatible
blood unit for a
patient who has an
anti-K, anti-E and
anti-S?

A. 1
B. 3
C. 9
D. 5

A

B. 3

25
Q

Which
antigen on
the antigram
is NOT low
incident?

A. Cw
B. V
C. Kpa
D. f

A

D. f

26
Q

Which of
the following
antibodies can
be naturally
occurring?

A. anti-K
B. anti-D
C. anti-S
D. anti-P1

A

D. anti-P1

27
Q

Choose
the true
statement
for Anti-K.

A. Agglutinates in the IS phase of
testing
B. Is usually IgM
C. Loses reactivity when tested with
DTT treated cells
D. Does not agglutinate with K+k+
cells

A

C. Loses reactivity when tested with
DTT treated cells

28
Q

Chronic
granulomatous
disease is
associated with a
depression of
the antigens in
the __system.

A. Duffy
B. Kidd
C. Kell
D. P

A

C. Kell

29
Q

Which of these
lesser known
antigens is not on
the antigram
because it is not
clinically significant?

A. Ch
B. Dia
C. Ge2
D. Ytb

A

A. Ch

30
Q

A patient
transfused 2 years
ago had anti-Jkb.
Now their screen is
negative. What is
the appropriate
followup?

A. Antibody panel
B. Phenotype the patient for Jkb
C. Phenotype units for Jkb
D. Immediate spin Crossmatch

A

C. Phenotype units for Jkb

31
Q

An antibody
that reacts with
all cells on a
panel except the
autocontrol is
referred to as…

A. High Titer Low Avidity
B. High Incidence
C. Low Incidence
D. Auto Antibody

A

B. High Incidence

32
Q

An
antibody’s
clinical
significance
refers to its
ability to cause

A. HDN
B. HTR
C. Formation of antibody
D. Two of these

A

D. Two of these

33
Q

True or False,
after neutralization
procedures, the
patient plasma
mixed with antigen
positive cell should
produce an
agglutination result.

A

F

34
Q

For what
purpose would
you choose a
heterozygous
cell?

A. Rule out
B. Rule in
C. Positive control for Phenotype
D. Negative control for Phenotype

A

C. Positive control for Phenotype

35
Q

Which of the
following stock
antibodies would be
an appropriate
negative control
after enzymatic
treatment of a panel?

A. Anti-c
B. Anti-Fyb
C. Anti-K
D. Anti-Jka

A

B. Anti-Fyb

36
Q

Which of the
following is NOT a
technique used to
pretreat a red cell
panel for complex
antibody
identification?

A. Hydatid Cyst fluid
B. Ficin
C. Papain
D. DTT

A

A. Hydatid Cyst fluid

37
Q

You are working on a patient
you suspect has a high incidence
antibody. You have only been
able to authorize plasma
transfusion for this patient while
you wait for reference lab
workup. The patient’s most
recent sample is now giving
negative results after plasma
transfusion. What has happened?

A. The Chido/Rodgers antibody was
neutralized by normal plasma.
B. The autoantibody was diluted by
plasma transfusion.
C. The Lewis antibody was neutralized
by normal plasma.
D. The incorrect patient was collected.

A

A. The Chido/Rodgers antibody was
neutralized by normal plasma.

38
Q

You are
attempting to
differentiate anti-S
from anti-M which
of the following
information is most
helpful.

A. The patient diagnosis is Malarial
infection.
B. The patient antibody reacts with 8
out of 12 cells on the antigram.
C. The patient antibody is non
agglutinating with enzyme treated
panel.
D. The patient has an ABO discrepancy
of extra reactions in the reverse
type.

A

D. The patient has an ABO discrepancy
of extra reactions in the reverse
type.