Practice of Endo

Question 1

Is intimately linked to a conceptual framework for understanding hormone secretion, hormone action, and principles of feedback control.

Answer 1

practice of endocrinology

Question 2

are treated with physiologic hormone replacement; hormone excess conditions, which usually are caused by benign glandular adenomas, are managed by removing tumors surgically or reducing hormone levels medically.

Answer 2

Endocrine deficiency disorders

Question 3

• a Greek phrase meaning “to set in motion,”
• describes the dynamic actions of hormones as they elicit cellular responses and regulate physiologic processes through feedback mechanisms.

Answer 3

Hormone

Question 4

he classic endocrine glands

Answer 4

• pituitary,
• thyroid,
• parathyroid,
• pancreatic islets,
• adrenals,
• gonads

Question 5

Endocrine diseases can be divided into three major types of conditions:

Answer 5

(1) hormone excess,
(2) hormone deficiency
(3) hormone resistance

Question 6

the physical examination usually focuses on the manifestations of hormone excess or deficiency as well as direct examination of palpable glands, such as the thyroid and gonads

Answer 6

Relatively inaccessible

Question 7

Requires knowledge of disease prevalence and pathophysiology

Answer 7

Clinical judgment

Question 8

These tests generally are employed only after a hormonal abnormality has been established by

Answer 8

biochemical Testing

Question 9

— most important diagnostic tool in endocrinology
— allow sensitive, specific, and quantitative determination of steady-state and dynamic changes in hormone conc.
— use antibodies to detect specific hormones

Answer 9

Immunoassays

Question 10

— 24h collections provide an integrated
assessment of the production of ad hormone or metabolite, many of which vary during the day.
— Measurement of creatinine
* an internal control for the adequacy of collection and can be used to normalize some hormone measurements.

Answer 10

Urinary Hormone Determinations

Question 11

— useful to separate the two groups (normal
vs abnormal)
— based on principles of feedback regulation, and most responses can be rationalized based on principles that govern the regulation of endocrine axes

Answer 11

Dynamic Testing

Question 12

Suppression tests are used in the setting of
suspected

Answer 12

endocrine hyperfunction

Question 13

Stimulation tests generally are used to
assess

Answer 13

endocrine hypofunction